iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062452

Ensembl Protein ID

ENSMODP00000005573.2

UniProt Accession

F6UR88; F6UR88_MONDO

Protein Name

Inhibitor of growth protein

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004518.3	ENSMODT00000005692.3	ENSMODP00000005573.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.60e-09	36.5	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDEYYEKFKR 60
ETDSVQKRRV LHCIQRSLIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFETCQEAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGTC CTGCAAACGG GGAGCAGATT CACCTGGTGA ACTATGTGGA GGATTATCTG 60
GACTCCATCG AGTCCCTGCC TTTCGATCTG CAGAGAAACG TCTCCTTGAT GAGGGAAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

KEGG

mdo:100017205

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	95.70	7.00e-132	462.00
IUUC-Apl-003910	Anas platyrhynchos	96.04	1.00e-132	465.00
IUUC-Aca-004874	Anolis carolinensis	95.36	8.00e-131	459.00
IUUC-Aly-005815	Arabidopsis lyrata	80.00	2.00e-28	119.00
IUUC-Ath-006765	Arabidopsis thaliana	76.36	1.00e-27	116.00
IUUC-Acl-008091	Aspergillus clavatus	52.11	1.00e-18	88.60
IUUC-Ate-010297	Aspergillus terreus	52.11	8.00e-19	89.00
IUUC-Ame-011262	Astyanax mexicanus	68.28	2.00e-97	348.00
IUUC-Bta-013507	Bos taurus	89.32	4.00e-93	333.00
IUUC-Cja-018925	Callithrix jacchus	90.32	3.00e-124	437.00
IUUC-Cfa-020947	Canis familiaris	96.06	9.00e-132	462.00
IUUC-Cpo-022286	Cavia porcellus	91.53	1.00e-100	359.00
IUUC-Csa-023825	Chlorocebus sabaeus	89.96	1.00e-123	436.00
IUUC-Cho-024577	Choloepus hoffmanni	95.71	5.00e-103	366.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.00
IUUC-Dno-029834	Dasypus novemcinctus	97.85	3.00e-134	471.00
IUUC-Dor-030315	Dipodomys ordii	89.32	5.00e-109	387.00
IUUC-Dse-031323	Dothistroma septosporum	60.00	8.00e-18	85.90
IUUC-Ete-032408	Echinops telfairi	93.19	4.00e-99	354.00
IUUC-Eca-034244	Equus caballus	93.59	7.00e-103	366.00
IUUC-Fca-035391	Felis catus	89.96	5.00e-111	393.00
IUUC-Fal-036838	Ficedula albicollis	95.34	2.00e-132	464.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.50
IUUC-Gga-040619	Gallus gallus	95.34	4.00e-132	463.00
IUUC-Gac-041996	Gasterosteus aculeatus	63.60	5.00e-96	343.00
IUUC-Ggo-045481	Gorilla gorilla	87.29	5.00e-97	347.00
IUUC-Hsa-046170	Homo sapiens	87.29	6.00e-97	347.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	97.01	7.00e-106	376.00
IUUC-Lch-050397	Latimeria chalumnae	91.76	1.00e-128	452.00
IUUC-Loc-052038	Lepisosteus oculatus	81.40	1.00e-101	362.00
IUUC-Lma-053234	Leptosphaeria maculans	53.45	3.00e-15	77.40
IUUC-Laf-054126	Loxodonta africana	96.42	2.00e-132	464.00
IUUC-Mcc-055031	Macaca mulatta	87.66	2.00e-96	345.00
IUUC-Meu-056248	Macropus eugenii	96.64	3.00e-108	384.00
IUUC-Mga-059217	Meleagris gallopavo	94.42	1.00e-103	368.00
IUUC-Mmr-061581	Microcebus murinus	94.24	2.00e-108	384.00
IUUC-Mmu-063412	Mus musculus	93.55	2.00e-128	451.00
IUUC-Mpu-066479	Mustela putorius furo	94.87	3.00e-104	371.00
IUUC-Mlu-067586	Myotis lucifugus	81.85	5.00e-121	426.00
IUUC-Nle-069122	Nomascus leucogenys	89.61	3.00e-123	434.00
IUUC-Opr-070835	Ochotona princeps	85.41	2.00e-85	308.00
IUUC-Ont-071606	Oreochromis niloticus	60.78	1.00e-90	325.00
IUUC-Oan-073023	Ornithorhynchus anatinus	93.55	2.00e-127	447.00
IUUC-Ocu-073779	Oryctolagus cuniculus	88.33	5.00e-95	340.00
IUUC-Ola-086891	Oryzias latipes	65.36	7.00e-97	346.00
IUUC-Oga-087954	Otolemur garnettii	93.55	5.00e-129	453.00
IUUC-Oar-090006	Ovis aries	91.04	4.00e-125	440.00
IUUC-Ptr-090589	Pan troglodytes	89.96	8.00e-124	436.00
IUUC-Pan-091896	Papio anubis	87.66	1.00e-96	346.00
IUUC-Psi-093266	Pelodiscus sinensis	96.06	2.00e-133	467.00
IUUC-Pma-094265	Petromyzon marinus	75.34	6.00e-34	136.00
IUUC-Pfo-097531	Poecilia formosa	61.04	9.00e-94	336.00
IUUC-Pab-098253	Pongo abelii	89.96	1.00e-123	435.00
IUUC-Pva-102753	Pteropus vampyrus	84.56	8.00e-94	337.00
IUUC-Pte-104284	Pyrenophora teres	53.45	2.00e-15	78.20
IUUC-Pyt-104787	Pyrenophora triticirepentis	55.17	2.00e-15	78.20
IUUC-Rno-105964	Rattus norvegicus	92.31	2.00e-92	331.00
IUUC-Sha-107270	Sarcophilus harrisii	98.21	5.00e-135	473.00
IUUC-Tgu-116822	Taeniopygia guttata	95.34	2.00e-132	464.00
IUUC-Tru-118262	Takifugu rubripes	57.14	4.00e-78	284.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.65	4.00e-84	304.00
IUUC-Tre-121950	Trichoderma reesei	64.29	3.00e-19	90.90
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.40
IUUC-Ttr-128672	Tursiops truncatus	91.49	2.00e-100	358.00
IUUC-Xtr-132200	Xenopus tropicalis	87.10	1.00e-119	422.00
IUUC-Xma-133491	Xiphophorus maculatus	61.64	3.00e-95	341.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence