iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059605

UUCD1 version

UUC-MeG-00262

Ensembl Protein ID

ENSMGAP00000005192.2

UniProt Accession

G1N147; G1N147_MELGA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000017034.1	ENSMGAT00000005924.2	ENSMGAP00000005192.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.20e-68	229.0	618	895

Active Site

Position(s)	Description	Evidence
863	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 47   sendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaesdieel 135
           s+++++  +  ++       h + F ++G+llg+a++++   + p++++++k++ +++ +ledlee++p + ++lk i++  es+ + +
   Q: 618  SAEESSVPSLFRHHQ--ASSHGDTFLLAGTLLGMAIYNHCHTPFPFPRALFKKMRDVEPTLEDLEELMPAVGRNLKNILKE-ESEHKLE 703
           444443333333333..348999********************************************************88.7899999 PP
   S: 136  gldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeei 224
           +l++tf         tk++ +  +G+ni Vt+ N++e+v+l+v+y l+e++++ +e f +Gf++ +p e+ ++F + el++l+ G +++
   Q: 704  SLQMTFV--------TKHYPITKNGANILVTMHNRKEFVDLYVNYMLNESVQKPFEDFMRGFSRGCPAESWKMFLPVELSILLLGHTNY 784
           99***98........7778899******************************************************************* PP
   S: 225  dvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkL 310
           d++ lkk++ky   y++++++i +Fw v++++ +e++k+fL F++gs+r+ + G++++    f i++   ++ d+++Ps+ TC ++L L
   Q: 785  DWHLLKKNAKYVY-YKQSHQTIMNFWTVFHKLPEEKKKKFLAFISGSDRIVPYGLEYFV---FFIEDplcENPDNSYPSARTCNYTLFL 869
           ***********77.********************************************9...999999*99999*************** PP
   S: 311  PeYsskeilkekLlyAieetkgFels 336
           P+Ysskeil+ekLl+Aie+++gF+ls
   Q: 870  PKYSSKEILEEKLLFAIEYNEGFGLS 895
           ***********************985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

CSLVKELENH SIVQIACGDH HSMALSTGGA LFTWGRNTHG QLGVGSQDPL ISNPQLVKGL 60
QGIPLAQIAA GGAHSVVVSL SGAVYSWGKN NFGQLGLGHT EDRDCPSYVE ALEHWKAVFI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTAGTCTGG TGAAAGAACT GGAAAACCAC AGTATTGTTC AAATAGCCTG TGGAGACCAT 60
CATTCCATGG CACTGTCCAC AGGTAGCCTC TTTTATGCGC TCTTTTCCTC CAAATGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005342	Anolis carolinensis	45.41	0.00e+00	710.00
IUUC-Dre-027898	Danio rerio	38.88	9.00e-153	533.00
IUUC-Dor-030862	Dipodomys ordii	50.18	1.00e-75	277.00
IUUC-Fal-037529	Ficedula albicollis	55.62	0.00e+00	912.00
IUUC-Gga-041079	Gallus gallus	71.01	0.00e+00	1201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence