iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026647

Ensembl Protein ID

ELA31695

UniProt Accession

L2FZY9; L2FZY9_COLGN

Genbank Protein ID

ELA31695.1

Protein Name

Ubiquitin-protein ligase

Genbank Nucleotide ID

KB020738

Gene Name

CGGC5_8164

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_8164	ELA31695	ELA31695

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.60e-117	392.3	3705	4036

Active Site

Position(s)	Description	Evidence
4005	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           ++k+ +l+++f +Eeg+d+gGvtre+++ ls++++++++ lf+  ++d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+ +s+++yk++l
   Q: 3705 EMKYgKLNIRFHNEEGVDAGGVTREWFQVLSRQMFDANYALFTPVSSDRTTFHPNSLSGI-NDEHLMFFKFIGRIIGKALYEGRVLDCYFSRAVYKRIL 3802
           56655899***************************************************9.56************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnev 200
           gk++s++d+e++dp++yksl ++++n   di+++ ++ tfsv+++++g t++ +L+p+G++i Vt+eNk++Yv+lvve++l ++++eq+e+f +Gf+++
   Q: 3803 GKSVSVKDMESFDPDYYKSLVWMLDN---DITDI-ITETFSVEDDEFGVTRTIDLCPNGRDIAVTEENKHDYVRLVVEHKLLSSVREQMEHFLKGFHDI 3897
           ************************99...99999.999************************************************************* PP
   S: 201  iplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.das 294
           ip +l+s+F+e+elelli+G ++idv+d+k++t+y++ yt++s++iqwFw+++++f++eer+++LqFvTg+s++Pl+Gf+el+     ++f i++ +++
   Q: 3898 IPADLISIFNEQELELLISGLPDIDVDDWKSNTEYHN-YTPSSQQIQWFWRAIRSFDKEERAKLLQFVTGTSKVPLNGFKELEgmngINRFNIHRdYGN 3995
           ***********************************66.*********************************************9999666777776899 PP
   S: 295  ddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           ++rlPss+TCfn+L+LPeY+s+e+l+ + + Ai+ + + F+
   Q: 3996 KERLPSSHTCFNQLDLPEYESYETLRAQVMKAITAGsDYFG 4036
           9********************************99866665 PP

Organism

Colletotrichum gloeosporioides

Protein Sequence
(Fasta)

MGKITKQMQP KHAETLSPWL KDFVTSACST PLPLLPDHLA KFPTRWPFPR GDLYHWIPLL 60
NRFDNILDCF CTTYSLDQGP QGRDFACELL LNTGTKTESY GDETWDTERL SKLGYNQDGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAGA TAACGAAGCA GATGCAGCCT AAGCATGCCG AGACTTTGGT TAGTTCCCCT 60
CCAACTCGCA GACCTCCTCA TTTGCCCGTC ACCTTACTAA CCTCACCCAG TCTCCATGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	31.00	6.00e-123	435.00
IUUC-Aml-001684	Ailuropoda melanoleuca	52.44	1.00e-136	481.00
IUUC-Atr-003044	Amborella trichopoda	42.20	4.00e-138	486.00
IUUC-Apl-003729	Anas platyrhynchos	51.83	6.00e-101	358.00
IUUC-Aca-005263	Anolis carolinensis	52.67	2.00e-137	484.00
IUUC-Aly-006157	Arabidopsis lyrata	40.21	2.00e-138	486.00
IUUC-Ath-007160	Arabidopsis thaliana	42.59	9.00e-136	478.00
IUUC-Ago-008005	Ashbya gossypii	56.67	0.00e+00	730.00
IUUC-Acl-008254	Aspergillus clavatus	35.64	0.00e+00	1238.00
IUUC-Afl-008712	Aspergillus flavus	57.87	0.00e+00	1226.00
IUUC-Afu-009022	Aspergillus fumigatus	58.49	0.00e+00	1224.00
IUUC-Ani-009412	Aspergillus nidulans	57.47	0.00e+00	1191.00
IUUC-Ang-009771	Aspergillus niger	36.35	0.00e+00	1283.00
IUUC-Aor-010186	Aspergillus oryzae	56.26	0.00e+00	1197.00
IUUC-Ate-010253	Aspergillus terreus	35.23	0.00e+00	1241.00
IUUC-Ame-011067	Astyanax mexicanus	53.08	4.00e-136	479.00
IUUC-Bgr-012043	Blumeria graminis	41.30	0.00e+00	1562.00
IUUC-Bta-012813	Bos taurus	52.44	1.00e-136	481.00
IUUC-Bci-013995	Botrytis cinerea	63.04	0.00e+00	1320.00
IUUC-Bdi-014884	Brachypodium distachyon	32.06	2.00e-143	503.00
IUUC-Bol-016533	Brassica oleracea	55.27	2.00e-93	333.00
IUUC-Bra-016637	Brassica rapa	32.90	8.00e-139	488.00
IUUC-Cel-018179	Caenorhabditis elegans	51.42	1.00e-128	454.00
IUUC-Cja-018741	Callithrix jacchus	52.89	2.00e-136	480.00
IUUC-Cfa-020083	Canis familiaris	52.44	1.00e-136	481.00
IUUC-Cpo-021923	Cavia porcellus	42.86	2.00e-97	350.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	50.59	7.00e-133	465.00
IUUC-Csa-023853	Chlorocebus sabaeus	52.44	1.00e-136	481.00
IUUC-Cho-024718	Choloepus hoffmanni	57.38	5.00e-125	442.00
IUUC-Cin-025627	Ciona intestinalis	51.18	8.00e-130	458.00
IUUC-Csv-025872	Ciona savignyi	51.42	1.00e-126	444.00
IUUC-Cne-027095	Cryptococcus neoformans	36.54	0.00e+00	637.00
IUUC-Cme-027267	Cyanidioschyzon merolae	48.82	1.00e-117	416.00
IUUC-Dre-028525	Danio rerio	50.96	2.00e-122	434.00
IUUC-Dno-029680	Dasypus novemcinctus	52.44	1.00e-136	481.00
IUUC-Dor-030902	Dipodomys ordii	47.33	1.00e-114	408.00
IUUC-Dse-031197	Dothistroma septosporum	56.12	0.00e+00	1167.00
IUUC-Dme-032122	Drosophila melanogaster	51.50	5.00e-138	486.00
IUUC-Eca-033915	Equus caballus	51.45	1.00e-134	474.00
IUUC-Eeu-034963	Erinaceus europaeus	52.11	2.00e-134	474.00
IUUC-Fca-035824	Felis catus	52.44	1.00e-136	481.00
IUUC-Fox-037756	Fusarium oxysporum	55.54	0.00e+00	2370.00
IUUC-Fso-038464	Fusarium solani	56.14	0.00e+00	2446.00
IUUC-Gmo-039073	Gadus morhua	52.00	2.00e-136	480.00
IUUC-Ggr-039946	Gaeumannomyces graminis	50.36	0.00e+00	2071.00
IUUC-Gga-040309	Gallus gallus	58.31	4.00e-107	379.00
IUUC-Gac-042430	Gasterosteus aculeatus	52.00	2.00e-136	480.00
IUUC-Gma-043112	Glycine max	40.15	1.00e-140	494.00
IUUC-Hsa-046879	Homo sapiens	52.44	1.00e-136	481.00
IUUC-Hvu-047697	Hordeum vulgare	31.93	1.00e-140	494.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	52.44	7.00e-137	480.00
IUUC-Kpa-049228	Komagataella pastoris	56.25	0.00e+00	742.00
IUUC-Lch-050252	Latimeria chalumnae	52.55	8.00e-137	481.00
IUUC-Lpe-050915	Leersia perrieri	42.61	6.00e-132	465.00
IUUC-Loc-052472	Lepisosteus oculatus	52.22	3.00e-137	483.00
IUUC-Lma-053159	Leptosphaeria maculans	56.44	0.00e+00	1198.00
IUUC-Laf-054154	Loxodonta africana	52.44	1.00e-136	481.00
IUUC-Mcc-055085	Macaca mulatta	52.44	2.00e-136	481.00
IUUC-Mor-057201	Magnaporthe oryzae	48.98	0.00e+00	2064.00
IUUC-Mpo-057597	Magnaporthe poae	52.20	0.00e+00	1516.00
IUUC-Mtr-058128	Medicago truncatula	39.85	7.00e-141	495.00
IUUC-Mla-058888	Melampsora laricipopulina	57.60	6.00e-146	508.00
IUUC-Mvi-060320	Microbotryum violaceum	49.70	0.00e+00	664.00
IUUC-Mmr-060820	Microcebus murinus	52.44	8.00e-137	481.00
IUUC-Mdo-062930	Monodelphis domestica	52.67	2.00e-137	483.00
IUUC-Mmu-063601	Mus musculus	52.44	1.00e-136	481.00
IUUC-Mac-065229	Musa acuminata	33.25	7.00e-148	518.00
IUUC-Mpu-066653	Mustela putorius furo	52.44	1.00e-136	481.00
IUUC-Mlu-067418	Myotis lucifugus	53.11	1.00e-136	481.00
IUUC-Nfi-068278	Neosartorya fischeri	68.64	0.00e+00	962.00
IUUC-Ncr-068813	Neurospora crassa	46.65	0.00e+00	1959.00
IUUC-Nle-069418	Nomascus leucogenys	52.44	1.00e-136	481.00
IUUC-Ont-071300	Oreochromis niloticus	52.00	3.00e-136	479.00
IUUC-Oan-073046	Ornithorhynchus anatinus	52.65	1.00e-136	481.00
IUUC-Ocu-074178	Oryctolagus cuniculus	53.11	6.00e-137	482.00
IUUC-Oba-075757	Oryza barthii	32.62	2.00e-143	503.00
IUUC-Obr-076553	Oryza brachyantha	32.59	1.00e-142	501.00
IUUC-Ogl-077520	Oryza glaberrima	32.59	1.00e-143	504.00
IUUC-Ogu-078278	Oryza glumaepatula	41.36	1.00e-135	477.00
IUUC-Oin-079767	Oryza indica	32.70	9.00e-144	504.00
IUUC-Olo-080380	Oryza longistaminata	41.08	1.00e-133	471.00
IUUC-Ome-081925	Oryza meridionalis	32.59	1.00e-141	497.00
IUUC-Oni-082619	Oryza nivara	32.41	6.00e-144	505.00
IUUC-Opu-083428	Oryza punctata	43.28	3.00e-133	469.00
IUUC-Oru-084501	Oryza rufipogon	32.73	7.00e-144	504.00
IUUC-Osa-086251	Oryza sativa	41.36	5.00e-135	473.00
IUUC-Olu-087813	Ostreococcus lucimarinus	45.61	1.00e-111	394.00
IUUC-Oga-088903	Otolemur garnettii	52.44	1.00e-136	481.00
IUUC-Oar-090210	Ovis aries	52.44	2.00e-136	480.00
IUUC-Pan-092368	Papio anubis	52.64	6.00e-124	439.00
IUUC-Pno-094871	Phaeosphaeria nodorum	56.68	0.00e+00	1181.00
IUUC-Ppa-095834	Physcomitrella patens	39.71	7.00e-143	501.00
IUUC-Pfo-096232	Poecilia formosa	52.00	2.00e-136	480.00
IUUC-Pab-098583	Pongo abelii	52.44	1.00e-136	481.00
IUUC-Pop-099468	Populus trichocarpa	37.41	1.00e-138	487.00
IUUC-Pca-100310	Procavia capensis	61.29	1.00e-89	325.00
IUUC-Ppe-102109	Prunus persica	40.26	1.00e-138	487.00
IUUC-Pva-102116	Pteropus vampyrus	49.78	1.00e-122	434.00
IUUC-Pgr-103465	Puccinia graminis	48.20	0.00e+00	652.00
IUUC-Ptt-103813	Puccinia triticina	40.02	0.00e+00	749.00
IUUC-Pte-104018	Pyrenophora teres	36.11	0.00e+00	1286.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	35.97	0.00e+00	1272.00
IUUC-Sce-106449	Saccharomyces cerevisiae	54.52	0.00e+00	712.00
IUUC-Sha-106961	Sarcophilus harrisii	52.67	4.00e-137	483.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	43.00	0.00e+00	835.00
IUUC-Spo-108024	Schizosaccharomyces pombe	43.32	0.00e+00	835.00
IUUC-Smo-109428	Selaginella moellendorffii	40.24	1.00e-137	484.00
IUUC-Sit-110598	Setaria italica	38.51	3.00e-139	489.00
IUUC-Sly-111706	Solanum lycopersicum	39.43	3.00e-138	486.00
IUUC-Stu-112908	Solanum tuberosum	27.32	6.00e-57	213.00
IUUC-Sar-113291	Sorex araneus	54.20	5.00e-132	466.00
IUUC-Sbi-114042	Sorghum bicolor	33.56	5.00e-148	518.00
IUUC-Sre-114958	Sporisorium reilianum	56.71	1.00e-176	610.00
IUUC-Ssc-115754	Sus scrofa	52.44	2.00e-136	481.00
IUUC-Tru-118570	Takifugu rubripes	52.00	2.00e-136	481.00
IUUC-Tni-120836	Tetraodon nigroviridis	50.89	2.00e-131	463.00
IUUC-Tca-121479	Theobroma cacao	31.53	2.00e-149	523.00
IUUC-Tre-121909	Trichoderma reesei	53.67	0.00e+00	2591.00
IUUC-Tvi-122370	Trichoderma virens	55.57	0.00e+00	2388.00
IUUC-Tae-125214	Triticum aestivum	31.71	2.00e-142	499.00
IUUC-Tme-127172	Tuber melanosporum	34.49	0.00e+00	1140.00
IUUC-Ttr-129253	Tursiops truncatus	52.44	2.00e-136	480.00
IUUC-Uma-129355	Ustilago maydis	56.19	8.00e-178	615.00
IUUC-Vda-129886	Verticillium dahliae	59.96	0.00e+00	2692.00
IUUC-Vpa-130708	Vicugna pacos	52.44	4.00e-136	479.00
IUUC-Vvi-131170	Vitis vinifera	44.20	1.00e-139	489.00
IUUC-Xtr-132123	Xenopus tropicalis	50.98	8.00e-128	451.00
IUUC-Xma-133869	Xiphophorus maculatus	52.00	2.00e-136	481.00
IUUC-Yli-134657	Yarrowia lipolytica	45.62	0.00e+00	904.00
IUUC-Zma-135581	Zea mays	33.16	2.00e-140	493.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence