iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108018

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Probable mRNA-splicing protein ubp10; Probable inactive ubiquitin-specific-processing protease 10

Genbank Nucleotide ID

CU329671

Gene Name

ubp10; SPBC577.07

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC577.07	SPBC577.07.1	SPBC577.07.1:pep

Annotation

mRNA Expression
GEO
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.80e-35	118.7	178	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaee.fsgyeqq 90
           +G++N+ N  Y+N v+ +L++++++r+++l k+  +++         +l++ l+ l+++lw  k  k++vsp+el++ +  ++++ +s +eq+
   Q: 178  VGMNNIKNNDYFNVVIHMLAHVKPFRNYFLLKNFDNCP---------QLVQRLAILIRKLWnhKAFKSHVSPQELIQEVTVLSHKkYSINEQK 261
           69*****************************4444444.........8*************9888899***********9988777******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk.............sqikclecdnvssreepfl 170
           D  Efl+++l++l++ l                       ++++  k +s+++  Fqg ++             +q++    + +++   pfl
   Q: 262  DPVEFLSWFLNTLHNCL---------------------GGKKSTIAKPTSIVHYSFQGFVRiesqkirqhaekgEQVVFTGDRVIQTNVVPFL 333
           *****************.....................23567889999999999999999999999999999999***9999999******* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldls 262
           +l+l++p k   + e   +++ +   +e l++   y+  + +++  +++++ l + P+++i+h+kRf   +++++ e++++ v+fpl  +d+s
   Q: 334  YLTLDLPPKPIFQDEFEGNIIPQVELKEILNK---YNGVHTQELAGMRRRFHLMTAPPYFIFHIKRF--MKNNYFTERNQTIVTFPLDdFDMS 421
           ********997766555677788888888876...66666666666779******************..78889******************* PP
   S: 263  pfcts..peekqkekkkYeLiavvvHsG.slssGHYvayvkn....ekgkWllfdDskVtevkeeevleetgstaYvlf 334
           pf  +   +++ k ++kY+L+a ++H+  ++ +  ++ +  +    +++kW+++ D +V+e++ + +      + ++ +
   Q: 422  PFIDDsfIQSNPKISTKYNLVANIIHESvTHAEEEFHNFRIQirnpSTNKWYQIQDLYVEEISSDMIRL---GESFIQL 497
           *99994434445559*******************9999988865566677************9988876...5555555 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

May play a role in mRNA splicing. It is unsure if the protein really exhibits hydrolase activity. Could be a competitor of ubiquitin C-terminal hydrolases (UCHs) (By similarity).

Protein Sequence
(Fasta)

MSENKDKNNI LKRHIEEDNN IDNGKRKKLE LGKDMEDVHD IASKEMEEHE TTPIISQNLY 60
LDTINRKLLD FDFEKVCSVS LTNLSVYACL VCGRYFQGRG PSSHAYFHAL TENHHVFVNC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATACTTCCA TACGACTTAG TAACTGAAGT TATCGATAGA TGGTAAAGCT TCAAAAATGT 60
CAGAAAATAA GGATAAAAAT AATATTTTAA AACGCCATAT TGAAGAAGAT AATAATATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0747--Spliceosome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033809--USP39
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0005634--C:nucleus
GO:0005681--C:spliceosomal complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0045292--P:mRNA cis splicing, via spliceosome
GO:0016579--P:protein deubiquitination
GO:0000245--P:spliceosomal complex assembly

KEGG

spo:SPBC577.07

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000483	Aegilops tauschii	43.18	4.00e-96	343.00
IUUC-Aml-001846	Ailuropoda melanoleuca	47.60	3.00e-113	400.00
IUUC-Atr-002758	Amborella trichopoda	42.29	2.00e-98	351.00
IUUC-Apl-003336	Anas platyrhynchos	35.79	5.00e-59	219.00
IUUC-Aca-004846	Anolis carolinensis	46.68	4.00e-109	386.00
IUUC-Aly-005683	Arabidopsis lyrata	43.18	3.00e-91	326.00
IUUC-Ath-007661	Arabidopsis thaliana	42.28	8.00e-92	328.00
IUUC-Ago-007802	Ashbya gossypii	34.44	1.00e-73	268.00
IUUC-Acl-008304	Aspergillus clavatus	48.79	6.00e-116	409.00
IUUC-Afl-008735	Aspergillus flavus	60.50	1.00e-42	165.00
IUUC-Afu-009100	Aspergillus fumigatus	48.16	2.00e-112	397.00
IUUC-Ani-009138	Aspergillus nidulans	48.48	2.00e-117	414.00
IUUC-Ang-009661	Aspergillus niger	52.43	2.00e-118	417.00
IUUC-Aor-010235	Aspergillus oryzae	44.60	4.00e-100	356.00
IUUC-Ate-010346	Aspergillus terreus	43.03	3.00e-92	330.00
IUUC-Ame-011688	Astyanax mexicanus	46.96	5.00e-113	399.00
IUUC-Bgr-011998	Blumeria graminis	52.55	2.00e-136	476.00
IUUC-Bta-013407	Bos taurus	47.38	5.00e-113	399.00
IUUC-Bci-013977	Botrytis cinerea	49.70	2.00e-137	480.00
IUUC-Bdi-014361	Brachypodium distachyon	42.95	8.00e-98	348.00
IUUC-Bol-016317	Brassica oleracea	43.50	8.00e-92	328.00
IUUC-Bra-016694	Brassica rapa	41.57	4.00e-100	356.00
IUUC-Cel-018491	Caenorhabditis elegans	41.07	4.00e-102	363.00
IUUC-Cja-019134	Callithrix jacchus	47.38	4.00e-113	399.00
IUUC-Cfa-020098	Canis familiaris	47.60	6.00e-113	399.00
IUUC-Cpo-021595	Cavia porcellus	47.38	9.00e-113	398.00
IUUC-Cre-022886	Chlamydomonas reinhardtii	28.23	2.00e-14	68.90
IUUC-Csa-024121	Chlorocebus sabaeus	47.38	5.00e-113	399.00
IUUC-Cho-025057	Choloepus hoffmanni	39.60	1.00e-36	145.00
IUUC-Cin-025473	Ciona intestinalis	40.51	7.00e-31	125.00
IUUC-Csv-025815	Ciona savignyi	50.00	3.00e-72	263.00
IUUC-Cgl-026416	Colletotrichum gloeosporioides	51.55	4.00e-137	479.00
IUUC-Cne-026802	Cryptococcus neoformans	44.61	2.00e-107	380.00
IUUC-Dre-027870	Danio rerio	46.61	1.00e-112	398.00
IUUC-Dno-029655	Dasypus novemcinctus	47.38	3.00e-113	400.00
IUUC-Dor-030762	Dipodomys ordii	47.38	6.00e-113	399.00
IUUC-Dse-031441	Dothistroma septosporum	49.13	1.00e-134	471.00
IUUC-Dme-032101	Drosophila melanogaster	44.89	3.00e-115	406.00
IUUC-Ete-032841	Echinops telfairi	44.32	2.00e-102	364.00
IUUC-Eca-033463	Equus caballus	47.38	4.00e-113	399.00
IUUC-Eeu-034438	Erinaceus europaeus	50.00	2.00e-56	211.00
IUUC-Fca-035774	Felis catus	47.60	5.00e-113	399.00
IUUC-Fal-036988	Ficedula albicollis	46.30	1.00e-113	401.00
IUUC-Fox-037895	Fusarium oxysporum	52.33	2.00e-137	480.00
IUUC-Fso-038450	Fusarium solani	53.22	4.00e-137	479.00
IUUC-Gmo-038874	Gadus morhua	45.61	3.00e-107	380.00
IUUC-Ggr-040115	Gaeumannomyces graminis	48.40	6.00e-123	432.00
IUUC-Gac-041650	Gasterosteus aculeatus	45.51	4.00e-110	389.00
IUUC-Gma-043697	Glycine max	43.10	3.00e-97	347.00
IUUC-Ggo-044707	Gorilla gorilla	43.38	6.00e-97	345.00
IUUC-Hsa-046041	Homo sapiens	47.38	7.00e-113	399.00
IUUC-Hvu-047816	Hordeum vulgare	41.70	6.00e-91	326.00
IUUC-Itr-048945	Ictidomys tridecemlineatus	50.77	3.00e-84	303.00
IUUC-Lch-050419	Latimeria chalumnae	47.05	2.00e-116	410.00
IUUC-Lpe-051593	Leersia perrieri	44.47	3.00e-100	357.00
IUUC-Loc-052930	Lepisosteus oculatus	46.72	1.00e-113	401.00
IUUC-Lma-053256	Leptosphaeria maculans	52.45	2.00e-139	487.00
IUUC-Laf-053555	Loxodonta africana	47.05	2.00e-111	394.00
IUUC-Mcc-055630	Macaca mulatta	47.38	5.00e-113	399.00
IUUC-Meu-056579	Macropus eugenii	42.24	5.00e-58	216.00
IUUC-Mor-057078	Magnaporthe oryzae	50.33	4.00e-123	432.00
IUUC-Mpo-057607	Magnaporthe poae	41.74	9.00e-101	358.00
IUUC-Mtr-058644	Medicago truncatula	42.03	1.00e-96	345.00
IUUC-Mla-059120	Melampsora laricipopulina	43.09	1.00e-115	408.00
IUUC-Mvi-060429	Microbotryum violaceum	50.87	2.00e-85	307.00
IUUC-Mmr-061313	Microcebus murinus	45.12	1.00e-113	401.00
IUUC-Mdo-062801	Monodelphis domestica	47.38	5.00e-113	399.00
IUUC-Mmu-064424	Mus musculus	47.82	7.00e-117	412.00
IUUC-Mac-064694	Musa acuminata	41.47	2.00e-94	337.00
IUUC-Mpu-065980	Mustela putorius furo	45.00	8.00e-93	332.00
IUUC-Mlu-067007	Myotis lucifugus	47.38	3.00e-113	400.00
IUUC-Nfi-068274	Neosartorya fischeri	48.16	8.00e-113	399.00
IUUC-Ncr-068829	Neurospora crassa	53.20	6.00e-133	465.00
IUUC-Nle-069171	Nomascus leucogenys	47.38	1.00e-112	398.00
IUUC-Opr-070494	Ochotona princeps	44.39	2.00e-89	320.00
IUUC-Ont-072290	Oreochromis niloticus	46.17	3.00e-114	403.00
IUUC-Oan-073099	Ornithorhynchus anatinus	47.16	5.00e-112	395.00
IUUC-Ocu-074642	Oryctolagus cuniculus	47.38	6.00e-113	399.00
IUUC-Oba-075886	Oryza barthii	43.36	4.00e-98	349.00
IUUC-Obr-076220	Oryza brachyantha	43.36	2.00e-99	354.00
IUUC-Ogl-077682	Oryza glaberrima	43.14	6.00e-98	349.00
IUUC-Ogu-078492	Oryza glumaepatula	42.92	4.00e-97	346.00
IUUC-Oin-079956	Oryza indica	43.14	6.00e-98	349.00
IUUC-Olo-080239	Oryza longistaminata	38.00	2.00e-78	285.00
IUUC-Ome-081573	Oryza meridionalis	42.70	7.00e-98	348.00
IUUC-Oni-082975	Oryza nivara	43.14	6.00e-98	349.00
IUUC-Opu-083724	Oryza punctata	43.36	4.00e-98	349.00
IUUC-Oru-084566	Oryza rufipogon	43.14	7.00e-98	349.00
IUUC-Osa-086008	Oryza sativa	43.14	7.00e-98	348.00
IUUC-Ola-086967	Oryzias latipes	45.73	5.00e-113	399.00
IUUC-Olu-087614	Ostreococcus lucimarinus	35.63	1.00e-70	258.00
IUUC-Oga-088047	Otolemur garnettii	41.35	4.00e-69	253.00
IUUC-Oar-089393	Ovis aries	47.60	5.00e-113	399.00
IUUC-Ptr-090561	Pan troglodytes	47.38	5.00e-113	399.00
IUUC-Pan-091812	Papio anubis	47.38	5.00e-113	399.00
IUUC-Psi-093507	Pelodiscus sinensis	44.52	2.00e-58	216.00
IUUC-Pno-095104	Phaeosphaeria nodorum	51.66	4.00e-136	476.00
IUUC-Ppa-095995	Physcomitrella patens	44.54	8.00e-101	358.00
IUUC-Pfo-096754	Poecilia formosa	47.05	8.00e-115	405.00
IUUC-Pab-098053	Pongo abelii	47.38	5.00e-113	399.00
IUUC-Pop-099158	Populus trichocarpa	43.50	1.00e-91	328.00
IUUC-Pca-100407	Procavia capensis	44.39	2.00e-89	321.00
IUUC-Ppe-101699	Prunus persica	41.19	1.00e-95	341.00
IUUC-Pva-103159	Pteropus vampyrus	46.72	3.00e-105	373.00
IUUC-Pgr-103433	Puccinia graminis	43.03	1.00e-118	418.00
IUUC-Ptt-103701	Puccinia triticina	40.45	1.00e-104	371.00
IUUC-Pte-104281	Pyrenophora teres	52.22	7.00e-137	478.00
IUUC-Pyt-104714	Pyrenophora triticirepentis	50.74	4.00e-137	479.00
IUUC-Rno-105531	Rattus norvegicus	47.26	1.00e-116	411.00
IUUC-Sce-106368	Saccharomyces cerevisiae	31.51	8.00e-61	225.00
IUUC-Sha-107093	Sarcophilus harrisii	47.38	8.00e-113	398.00
IUUC-Sja-108004	Schizosaccharomyces japonicus	62.75	0.00e+00	671.00
IUUC-Ssl-108460	Sclerotinia sclerotiorum	47.27	1.00e-127	448.00
IUUC-Smo-108892	Selaginella moellendorffii	40.81	2.00e-95	340.00
IUUC-Sit-110782	Setaria italica	44.20	3.00e-101	360.00
IUUC-Sly-111308	Solanum lycopersicum	41.12	4.00e-109	386.00
IUUC-Stu-112447	Solanum tuberosum	44.12	6.00e-109	385.00
IUUC-Sar-113352	Sorex araneus	45.92	3.00e-81	294.00
IUUC-Sbi-114806	Sorghum bicolor	44.32	1.00e-100	358.00
IUUC-Sre-115059	Sporisorium reilianum	50.00	1.00e-72	265.00
IUUC-Ssc-115677	Sus scrofa	50.46	3.00e-83	300.00
IUUC-Tru-118478	Takifugu rubripes	46.17	3.00e-112	396.00
IUUC-Tsy-119082	Tarsius syrichta	42.12	1.00e-70	258.00
IUUC-Tni-120419	Tetraodon nigroviridis	45.75	3.00e-106	376.00
IUUC-Tca-121294	Theobroma cacao	42.61	2.00e-104	371.00
IUUC-Tre-121962	Trichoderma reesei	50.77	2.00e-125	441.00
IUUC-Tvi-122280	Trichoderma virens	50.66	1.00e-132	464.00
IUUC-Tae-124442	Triticum aestivum	43.83	2.00e-101	360.00
IUUC-Tur-126551	Triticum urartu	43.61	4.00e-100	356.00
IUUC-Tme-126959	Tuber melanosporum	53.23	6.00e-142	495.00
IUUC-Tbe-127737	Tupaia belangeri	46.67	1.00e-108	384.00
IUUC-Ttr-129211	Tursiops truncatus	54.78	8.00e-73	265.00
IUUC-Uma-129591	Ustilago maydis	38.89	1.00e-97	348.00
IUUC-Vda-129674	Verticillium dahliae	49.89	2.00e-121	427.00
IUUC-Vpa-130793	Vicugna pacos	43.65	1.00e-95	341.00
IUUC-Xtr-132430	Xenopus tropicalis	45.97	2.00e-112	397.00
IUUC-Xma-133515	Xiphophorus maculatus	47.05	9.00e-115	405.00
IUUC-Yli-134488	Yarrowia lipolytica	42.06	1.00e-97	347.00
IUUC-Zma-134748	Zea mays	44.32	1.00e-100	358.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence