iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118575

UUCD1 version

UUC-TaR-00800

Ensembl Protein ID

ENSTRUP00000037689.1

UniProt Accession

H2UL68; H2UL68_TAKRU

Protein Name

Uncharacterized protein

Gene Name

klhl42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000014743.1	ENSTRUT00000037825.1	ENSTRUP00000037689.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.10e-07	30.4	29	90
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.70e-06	27.3	120	146

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 5    lvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +v +++ +++ k  L   S++F+al +++++es+ ++ v++++++   ++ +l+F+ t+k+++
   Q: 29   IVMDDKIYEVNKKKLIEKSDYFRALYSSGMKEST-EDSVQLQGLSVPGLELVLEFINTSKVQI 90
           566799999************************9.************************9985 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           l+Nc++++++++ y+ +dL+ a+l+++
   Q: 120  LDNCVDLYSLSEVYGTHDLHNACLKYM 146
           79************************7 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QRPSTTNLSL KGRKRRISFI MSSDQVIAIV MDDKIYEVNK KKLIEKSDYF RALYSSGMKE 60
STEDSVQLQG LSVPGLELVL EFINTSKVQI VNETLEDLIE TASFLQVTSI LKLLTSEIRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAGGCCAA GCACAACAAA CCTCAGCCTT AAAGGACGAA AACGGCGAAT TAGCTTTATC 60
ATGTCATCCG ACCAGGTTAT CGCTATCGTC ATGGATGACA AAATATATGA GGTAAATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF01344--Kelch_1

SMART

SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0032886--P:regulation of microtubule-based process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002285	Ailuropoda melanoleuca	60.92	7.00e-169	586.00
IUUC-Apl-004005	Anas platyrhynchos	61.81	1.00e-172	599.00
IUUC-Aca-004932	Anolis carolinensis	53.67	1.00e-132	466.00
IUUC-Ame-011389	Astyanax mexicanus	83.19	0.00e+00	838.00
IUUC-Bta-013120	Bos taurus	59.01	1.00e-165	576.00
IUUC-Cfa-020969	Canis familiaris	59.53	4.00e-163	567.00
IUUC-Cpo-022181	Cavia porcellus	59.96	7.00e-165	573.00
IUUC-Csa-023917	Chlorocebus sabaeus	59.53	4.00e-164	571.00
IUUC-Cho-024950	Choloepus hoffmanni	54.08	2.00e-96	345.00
IUUC-Dre-028648	Danio rerio	81.36	0.00e+00	816.00
IUUC-Dno-028937	Dasypus novemcinctus	56.70	2.00e-146	511.00
IUUC-Dor-031019	Dipodomys ordii	48.10	5.00e-65	241.00
IUUC-Ete-032490	Echinops telfairi	58.20	1.00e-153	536.00
IUUC-Eca-033326	Equus caballus	60.44	1.00e-164	572.00
IUUC-Eeu-034985	Erinaceus europaeus	70.27	1.00e-60	227.00
IUUC-Fca-035493	Felis catus	65.86	4.00e-145	507.00
IUUC-Fal-036818	Ficedula albicollis	60.93	3.00e-143	501.00
IUUC-Gmo-039278	Gadus morhua	70.94	2.00e-99	355.00
IUUC-Gga-040470	Gallus gallus	62.81	9.00e-166	576.00
IUUC-Gac-041998	Gasterosteus aculeatus	89.10	0.00e+00	887.00
IUUC-Ggo-045547	Gorilla gorilla	59.49	5.00e-163	567.00
IUUC-Hsa-046283	Homo sapiens	59.53	3.00e-164	571.00
IUUC-Itr-048418	Ictidomys tridecemlineatus	61.24	2.00e-170	591.00
IUUC-Lch-049748	Latimeria chalumnae	71.61	0.00e+00	714.00
IUUC-Loc-052270	Lepisosteus oculatus	75.11	0.00e+00	765.00
IUUC-Laf-054165	Loxodonta africana	62.97	5.00e-146	510.00
IUUC-Mcc-054993	Macaca mulatta	53.80	3.00e-95	341.00
IUUC-Meu-056500	Macropus eugenii	70.99	1.00e-141	495.00
IUUC-Mga-059376	Meleagris gallopavo	63.22	4.00e-170	590.00
IUUC-Mmr-060782	Microcebus murinus	59.33	1.00e-165	576.00
IUUC-Mdo-062068	Monodelphis domestica	61.69	1.00e-165	576.00
IUUC-Mmu-064288	Mus musculus	60.56	6.00e-171	593.00
IUUC-Mpu-065815	Mustela putorius furo	59.53	4.00e-167	582.00
IUUC-Mlu-067560	Myotis lucifugus	59.56	2.00e-160	558.00
IUUC-Nle-069737	Nomascus leucogenys	59.53	3.00e-164	571.00
IUUC-Opr-070332	Ochotona princeps	59.49	8.00e-167	580.00
IUUC-Ont-072368	Oreochromis niloticus	91.70	0.00e+00	878.00
IUUC-Ocu-074509	Oryctolagus cuniculus	59.22	8.00e-164	570.00
IUUC-Ola-087330	Oryzias latipes	87.66	0.00e+00	880.00
IUUC-Oga-089095	Otolemur garnettii	58.94	3.00e-164	571.00
IUUC-Oar-090108	Ovis aries	70.79	9.00e-134	469.00
IUUC-Ptr-091031	Pan troglodytes	59.53	3.00e-164	571.00
IUUC-Pan-091834	Papio anubis	59.33	4.00e-162	564.00
IUUC-Psi-093483	Pelodiscus sinensis	64.45	5.00e-153	533.00
IUUC-Pfo-097126	Poecilia formosa	89.36	0.00e+00	895.00
IUUC-Pab-098446	Pongo abelii	59.41	2.00e-164	572.00
IUUC-Pca-100423	Procavia capensis	59.72	2.00e-166	578.00
IUUC-Pva-102436	Pteropus vampyrus	50.59	2.00e-51	196.00
IUUC-Rno-105244	Rattus norvegicus	60.56	4.00e-171	594.00
IUUC-Sha-107215	Sarcophilus harrisii	63.21	1.00e-172	599.00
IUUC-Ssc-115433	Sus scrofa	59.33	4.00e-167	580.00
IUUC-Tgu-116589	Taeniopygia guttata	58.40	7.00e-154	536.00
IUUC-Tsy-118895	Tarsius syrichta	59.47	1.00e-127	449.00
IUUC-Tni-119944	Tetraodon nigroviridis	92.21	0.00e+00	930.00
IUUC-Ttr-128828	Tursiops truncatus	69.70	3.00e-137	481.00
IUUC-Vpa-130506	Vicugna pacos	63.20	5.00e-128	450.00
IUUC-Xtr-131850	Xenopus tropicalis	46.12	7.00e-107	380.00
IUUC-Xma-133680	Xiphophorus maculatus	86.27	0.00e+00	895.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence