iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034378

UUCD1 version

UUC-EqC-00099

Ensembl Protein ID

ENSECAP00000006943.1

UniProt Accession

F6R6S6; F6R6S6_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000009008.1	ENSECAT00000009165.1	ENSECAP00000006943.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.20e-07	29.6	14	57
E3 activity/RING/U-box	3.20e-06	27.3	10	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++  CgH f++ Cl ++      + ++ +CP C+
   Q: 14   CPLCLQLFDA-PVTAECGHSFCRACLSRV-AGEPAADGTVLCPCCQ 57
           ********99.999***************.5555899999*****7 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl...asggk....tcPvtrqplteedlvPnltlrrli 65
           +e+ Cp+ l+l+  Pv++++G+++ r+++ +     a         cP +++p++++ l  n  l rl+
   Q: 10   QELSCPLCLQLFDAPVTAECGHSFCRACLSRVAgepA---AdgtvLCPCCQAPTRPQALSTNQQLARLV 75
           7899***************************765553...144479**************999998876 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCRACLSR VAGEPAADGT VLCPCCQAPT 60
RPQALSTNQQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RALVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGCCATG TCTGCTGCGC CCGGACTCTT GCACCAGGAG CTGTCCTGCC CGTTGTGCCT 60
GCAGCTGTTC GACGCGCCCG TGACCGCCGA GTGCGGCCAC AGCTTCTGCC GCGCCTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	78.01	0.00e+00	703.00
IUUC-Aca-004755	Anolis carolinensis	62.69	2.00e-171	595.00
IUUC-Bta-013476	Bos taurus	81.13	0.00e+00	734.00
IUUC-Cja-018969	Callithrix jacchus	82.64	0.00e+00	766.00
IUUC-Cfa-020155	Canis familiaris	95.81	0.00e+00	900.00
IUUC-Cpo-021646	Cavia porcellus	88.05	0.00e+00	823.00
IUUC-Csa-023855	Chlorocebus sabaeus	91.96	4.00e-174	603.00
IUUC-Dno-029142	Dasypus novemcinctus	90.78	0.00e+00	784.00
IUUC-Dor-030394	Dipodomys ordii	66.24	3.00e-85	308.00
IUUC-Ete-032801	Echinops telfairi	86.05	5.00e-66	244.00
IUUC-Eeu-034526	Erinaceus europaeus	85.99	0.00e+00	755.00
IUUC-Fca-036440	Felis catus	95.18	0.00e+00	921.00
IUUC-Ggo-045086	Gorilla gorilla	95.61	0.00e+00	690.00
IUUC-Hsa-046533	Homo sapiens	94.13	0.00e+00	855.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	93.29	0.00e+00	877.00
IUUC-Laf-054479	Loxodonta africana	91.61	0.00e+00	860.00
IUUC-Mcc-055814	Macaca mulatta	92.28	0.00e+00	824.00
IUUC-Meu-056767	Macropus eugenii	73.19	0.00e+00	691.00
IUUC-Mmr-061616	Microcebus murinus	93.08	0.00e+00	873.00
IUUC-Mdo-062252	Monodelphis domestica	76.41	0.00e+00	726.00
IUUC-Mmu-063094	Mus musculus	90.15	0.00e+00	851.00
IUUC-Mpu-065885	Mustela putorius furo	80.71	0.00e+00	697.00
IUUC-Mlu-068150	Myotis lucifugus	64.46	5.00e-84	303.00
IUUC-Nle-069476	Nomascus leucogenys	94.35	0.00e+00	854.00
IUUC-Opr-070871	Ochotona princeps	90.60	6.00e-142	497.00
IUUC-Oan-072738	Ornithorhynchus anatinus	76.11	0.00e+00	715.00
IUUC-Ocu-074132	Oryctolagus cuniculus	76.10	0.00e+00	660.00
IUUC-Olu-087666	Ostreococcus lucimarinus	39.19	3.00e-10	59.70
IUUC-Oga-088268	Otolemur garnettii	63.81	4.00e-148	517.00
IUUC-Oar-089555	Ovis aries	70.95	1.00e-175	608.00
IUUC-Ptr-090792	Pan troglodytes	94.13	0.00e+00	855.00
IUUC-Pan-092897	Papio anubis	94.13	0.00e+00	855.00
IUUC-Pab-098716	Pongo abelii	94.13	0.00e+00	854.00
IUUC-Pca-100618	Procavia capensis	82.18	0.00e+00	762.00
IUUC-Pva-102430	Pteropus vampyrus	85.32	0.00e+00	777.00
IUUC-Rno-105665	Rattus norvegicus	90.78	0.00e+00	882.00
IUUC-Sha-106854	Sarcophilus harrisii	64.94	4.00e-174	604.00
IUUC-Sar-113028	Sorex araneus	89.38	1.00e-150	525.00
IUUC-Ssc-116124	Sus scrofa	94.71	0.00e+00	856.00
IUUC-Tbe-127273	Tupaia belangeri	88.98	1.00e-124	439.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence