iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040998

Ensembl Protein ID

ENSGALP00000010193.4

UniProt Accession

E1BWW2; E1BWW2_CHICK

Genbank Protein ID

ENSGALP00000010193

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000238

Gene Name

TSG101

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000006312.6	ENSGALT00000010207.5	ENSGALP00000010193.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/UBC-like/UBD_UEV	2.00e-63	212.8	2	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwlletYPekPPfvsvk 89
           A ses+lkk+  kyk+++lt++e+  +i++yk+lkp+++s+v+nDg+sreL++l Gtipvp+rg++ynipi+lwll+tYP +PP+++vk
   Q: 2    AFSESQLKKMLAKYKYRDLTIQETNSVISQYKDLKPVMDSYVFNDGSSRELMSLSGTIPVPYRGNVYNIPICLWLLDTYPFNPPICFVK 90
           789************************************************************************************** PP
   S: 90   ekidmntikssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++m tik++ +hvd+nGki+lp+Lh+Wk+p+s+l+el+q++iv++++epp++srp
   Q: 91   PTSSM-TIKTG-KHVDANGKIYLPYLHEWKYPQSDLLELIQVMIVVFGEEPPVFSRP 145
           *****.*****.*******************************************98 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAFSESQLKK MLAKYKYRDL TIQETNSVIS QYKDLKPVMD SYVFNDGSSR ELMSLSGTIP 60
VPYRGNVYNI PICLWLLDTY PFNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKYP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGCCGGGC GGAAGCGGGC GCGCGGCCGC TGCCTGTGTT GGGGGGGGGC GGGCGGCAGC 60
CGCCGCCATG GCGTTCTCCG AGAGCCAGCT GAAGAAAATG CTCGCTAAGG TAGGCGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0070062--C:extracellular exosome
GO:0005770--C:late endosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003714--F:transcription corepressor activity
GO:0046790--F:virion binding
GO:0007050--P:cell cycle arrest
GO:0006464--P:cellular protein modification process
GO:1990182--P:exosomal secretion
GO:0030216--P:keratinocyte differentiation
GO:0008285--P:negative regulation of cell proliferation
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1903543--P:positive regulation of exosomal secretion
GO:2000397--P:positive regulation of ubiquitin-dependent endocytosis
GO:1903774--P:positive regulation of viral budding via host ESCRT complex
GO:1902188--P:positive regulation of viral release from host cell
GO:0015031--P:protein transport
GO:0001558--P:regulation of cell growth
GO:1903551--P:regulation of extracellular exosome assembly
GO:0043405--P:regulation of MAP kinase activity
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046755--P:viral budding

KEGG

gga:423082

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	36.67	4.00e-21	95.50
IUUC-Aml-002415	Ailuropoda melanoleuca	87.72	0.00e+00	684.00
IUUC-Atr-002875	Amborella trichopoda	30.00	6.00e-40	158.00
IUUC-Apl-003473	Anas platyrhynchos	92.60	0.00e+00	718.00
IUUC-Aca-004573	Anolis carolinensis	85.46	0.00e+00	667.00
IUUC-Aly-006164	Arabidopsis lyrata	44.12	1.00e-21	97.10
IUUC-Ath-006575	Arabidopsis thaliana	31.69	6.00e-33	134.00
IUUC-Ago-007755	Ashbya gossypii	22.22	2.00e-05	43.90
IUUC-Acl-008218	Aspergillus clavatus	38.76	4.00e-26	112.00
IUUC-Afl-008597	Aspergillus flavus	40.31	5.00e-27	115.00
IUUC-Afu-009017	Aspergillus fumigatus	37.98	4.00e-24	105.00
IUUC-Ani-009468	Aspergillus nidulans	40.91	4.00e-22	99.40
IUUC-Ang-009755	Aspergillus niger	36.51	2.00e-23	103.00
IUUC-Aor-010072	Aspergillus oryzae	39.10	3.00e-27	116.00
IUUC-Ate-010400	Aspergillus terreus	38.76	2.00e-26	113.00
IUUC-Ame-011620	Astyanax mexicanus	81.40	0.00e+00	634.00
IUUC-Bgr-012136	Blumeria graminis	35.77	1.00e-23	104.00
IUUC-Bta-012557	Bos taurus	89.54	0.00e+00	689.00
IUUC-Bci-013881	Botrytis cinerea	38.85	1.00e-27	117.00
IUUC-Bdi-014001	Brachypodium distachyon	36.17	7.00e-13	67.80
IUUC-Bol-015933	Brassica oleracea	43.22	1.00e-24	107.00
IUUC-Bra-017442	Brassica rapa	43.22	8.00e-25	107.00
IUUC-Cel-018697	Caenorhabditis elegans	47.22	3.00e-37	149.00
IUUC-Cja-018963	Callithrix jacchus	85.46	0.00e+00	667.00
IUUC-Cfa-020472	Canis familiaris	87.47	0.00e+00	682.00
IUUC-Cpo-022001	Cavia porcellus	88.75	0.00e+00	688.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	29.65	3.00e-30	126.00
IUUC-Csa-023959	Chlorocebus sabaeus	86.45	0.00e+00	657.00
IUUC-Cho-024389	Choloepus hoffmanni	52.14	5.00e-37	148.00
IUUC-Cin-025688	Ciona intestinalis	45.98	8.00e-100	356.00
IUUC-Cne-026904	Cryptococcus neoformans	30.50	4.00e-17	82.80
IUUC-Cme-027280	Cyanidioschyzon merolae	35.56	5.00e-19	88.20
IUUC-Dre-027913	Danio rerio	82.43	3.00e-174	603.00
IUUC-Dno-029672	Dasypus novemcinctus	87.98	0.00e+00	692.00
IUUC-Dor-030175	Dipodomys ordii	85.50	5.00e-88	317.00
IUUC-Dse-031375	Dothistroma septosporum	34.31	5.00e-24	105.00
IUUC-Dme-031736	Drosophila melanogaster	47.60	5.00e-98	350.00
IUUC-Ete-032343	Echinops telfairi	84.40	0.00e+00	655.00
IUUC-Eca-033926	Equus caballus	87.98	0.00e+00	680.00
IUUC-Eeu-034940	Erinaceus europaeus	84.14	0.00e+00	664.00
IUUC-Fca-035491	Felis catus	87.47	0.00e+00	677.00
IUUC-Fal-037508	Ficedula albicollis	92.09	0.00e+00	712.00
IUUC-Fox-037937	Fusarium oxysporum	31.54	2.00e-21	97.10
IUUC-Fso-038091	Fusarium solani	34.56	9.00e-25	107.00
IUUC-Gmo-039427	Gadus morhua	77.52	9.00e-169	585.00
IUUC-Ggr-039724	Gaeumannomyces graminis	37.31	1.00e-24	108.00
IUUC-Gac-041356	Gasterosteus aculeatus	80.67	0.00e+00	638.00
IUUC-Gma-043566	Glycine max	38.89	2.00e-25	109.00
IUUC-Ggo-044967	Gorilla gorilla	86.45	0.00e+00	657.00
IUUC-Hsa-046686	Homo sapiens	86.45	0.00e+00	657.00
IUUC-Hvu-047430	Hordeum vulgare	36.67	3.00e-21	95.90
IUUC-Itr-047929	Ictidomys tridecemlineatus	96.88	2.00e-106	377.00
IUUC-Kpa-049287	Komagataella pastoris	29.95	2.00e-17	83.20
IUUC-Lch-050597	Latimeria chalumnae	84.18	0.00e+00	681.00
IUUC-Lpe-051090	Leersia perrieri	37.50	6.00e-21	94.70
IUUC-Loc-052399	Lepisosteus oculatus	82.52	2.00e-177	614.00
IUUC-Lma-053249	Leptosphaeria maculans	30.70	2.00e-13	70.90
IUUC-Laf-053766	Loxodonta africana	88.49	0.00e+00	685.00
IUUC-Mcc-055641	Macaca mulatta	86.45	0.00e+00	657.00
IUUC-Meu-055919	Macropus eugenii	88.04	5.00e-165	573.00
IUUC-Mor-056970	Magnaporthe oryzae	37.69	2.00e-24	106.00
IUUC-Mpo-057345	Magnaporthe poae	36.15	2.00e-22	100.00
IUUC-Mtr-058436	Medicago truncatula	38.89	2.00e-26	113.00
IUUC-Mla-059037	Melampsora laricipopulina	37.93	3.00e-27	116.00
IUUC-Mga-059263	Meleagris gallopavo	97.14	0.00e+00	761.00
IUUC-Mvi-060463	Microbotryum violaceum	30.19	2.00e-17	84.00
IUUC-Mmr-060915	Microcebus murinus	87.72	0.00e+00	679.00
IUUC-Mdo-062449	Monodelphis domestica	87.72	0.00e+00	667.00
IUUC-Mmu-063151	Mus musculus	86.70	0.00e+00	674.00
IUUC-Mac-065020	Musa acuminata	36.22	9.00e-24	104.00
IUUC-Mpu-066621	Mustela putorius furo	87.72	0.00e+00	684.00
IUUC-Mlu-067336	Myotis lucifugus	86.19	0.00e+00	666.00
IUUC-Nfi-068530	Neosartorya fischeri	38.76	3.00e-24	106.00
IUUC-Ncr-068785	Neurospora crassa	36.03	3.00e-25	109.00
IUUC-Nle-069972	Nomascus leucogenys	86.45	0.00e+00	657.00
IUUC-Opr-071150	Ochotona princeps	74.18	6.00e-80	290.00
IUUC-Ont-071366	Oreochromis niloticus	79.07	0.00e+00	634.00
IUUC-Oan-073290	Ornithorhynchus anatinus	93.81	9.00e-104	369.00
IUUC-Ocu-074351	Oryctolagus cuniculus	88.24	0.00e+00	684.00
IUUC-Oba-075338	Oryza barthii	26.03	3.00e-11	62.00
IUUC-Obr-076135	Oryza brachyantha	27.17	3.00e-29	122.00
IUUC-Ogl-077182	Oryza glaberrima	35.71	1.00e-17	83.60
IUUC-Ogu-078281	Oryza glumaepatula	27.64	1.00e-25	110.00
IUUC-Oin-079068	Oryza indica	35.71	4.00e-17	82.40
IUUC-Olo-080460	Oryza longistaminata	35.80	1.00e-08	52.40
IUUC-Ome-081781	Oryza meridionalis	27.20	8.00e-24	104.00
IUUC-Oni-082517	Oryza nivara	27.00	7.00e-24	105.00
IUUC-Opu-084101	Oryza punctata	36.28	1.00e-17	83.60
IUUC-Oru-084556	Oryza rufipogon	36.28	2.00e-17	83.20
IUUC-Osa-086264	Oryza sativa	35.71	2.00e-17	83.60
IUUC-Ola-087252	Oryzias latipes	92.62	5.00e-69	252.00
IUUC-Olu-087610	Ostreococcus lucimarinus	28.42	2.00e-17	83.20
IUUC-Oga-088304	Otolemur garnettii	88.49	0.00e+00	683.00
IUUC-Oar-089734	Ovis aries	89.54	0.00e+00	689.00
IUUC-Ptr-091476	Pan troglodytes	86.45	0.00e+00	657.00
IUUC-Pan-092341	Papio anubis	86.45	0.00e+00	657.00
IUUC-Psi-093470	Pelodiscus sinensis	86.23	0.00e+00	663.00
IUUC-Pma-094143	Petromyzon marinus	65.21	4.00e-134	470.00
IUUC-Pno-095069	Phaeosphaeria nodorum	34.91	6.00e-14	72.00
IUUC-Ppa-095933	Physcomitrella patens	29.62	9.00e-42	164.00
IUUC-Pfo-096321	Poecilia formosa	80.36	4.00e-175	607.00
IUUC-Pab-098527	Pongo abelii	84.99	1.00e-166	578.00
IUUC-Pop-099323	Populus trichocarpa	27.58	2.00e-37	149.00
IUUC-Pca-101044	Procavia capensis	70.08	6.00e-146	509.00
IUUC-Ppe-101458	Prunus persica	42.02	2.00e-27	116.00
IUUC-Pva-103014	Pteropus vampyrus	76.21	3.00e-161	560.00
IUUC-Pgr-103615	Puccinia graminis	38.35	2.00e-22	100.00
IUUC-Ptt-103826	Puccinia triticina	39.60	5.00e-17	82.40
IUUC-Pte-104171	Pyrenophora teres	35.29	4.00e-22	99.80
IUUC-Pyt-104433	Pyrenophora triticirepentis	33.01	2.00e-10	60.50
IUUC-Rno-105957	Rattus norvegicus	85.93	0.00e+00	669.00
IUUC-Sce-106262	Saccharomyces cerevisiae	26.98	7.00e-11	61.20
IUUC-Sha-107607	Sarcophilus harrisii	85.67	2.00e-170	591.00
IUUC-Spo-108175	Schizosaccharomyces pombe	29.63	3.30e-02	33.10
IUUC-Ssl-108672	Sclerotinia sclerotiorum	39.10	2.00e-27	117.00
IUUC-Smo-108973	Selaginella moellendorffii	38.46	1.00e-21	97.10
IUUC-Sly-111373	Solanum lycopersicum	38.89	2.00e-24	106.00
IUUC-Stu-112844	Solanum tuberosum	38.89	1.00e-23	103.00
IUUC-Sar-113653	Sorex araneus	76.80	3.00e-166	577.00
IUUC-Sbi-114390	Sorghum bicolor	35.00	1.00e-20	93.60
IUUC-Sre-115200	Sporisorium reilianum	37.67	6.00e-24	105.00
IUUC-Ssc-115888	Sus scrofa	88.11	2.00e-107	381.00
IUUC-Tgu-117506	Taeniopygia guttata	92.39	0.00e+00	729.00
IUUC-Tru-118063	Takifugu rubripes	79.18	2.00e-170	590.00
IUUC-Tsy-118851	Tarsius syrichta	70.40	3.00e-133	467.00
IUUC-Tni-120010	Tetraodon nigroviridis	79.49	1.00e-169	588.00
IUUC-Tca-121182	Theobroma cacao	41.27	2.00e-23	103.00
IUUC-Tre-122040	Trichoderma reesei	34.62	3.00e-22	99.80
IUUC-Tvi-122660	Trichoderma virens	37.50	1.00e-25	110.00
IUUC-Tae-124561	Triticum aestivum	36.67	4.00e-21	95.50
IUUC-Tur-126651	Triticum urartu	36.67	4.00e-21	95.10
IUUC-Tme-127184	Tuber melanosporum	47.32	2.00e-25	110.00
IUUC-Tbe-127894	Tupaia belangeri	79.50	3.00e-84	304.00
IUUC-Ttr-128264	Tursiops truncatus	84.14	0.00e+00	660.00
IUUC-Uma-129407	Ustilago maydis	38.57	1.00e-25	111.00
IUUC-Vda-130002	Verticillium dahliae	29.73	8.00e-17	81.60
IUUC-Vpa-130156	Vicugna pacos	79.50	6.00e-85	307.00
IUUC-Vvi-131479	Vitis vinifera	39.68	2.00e-24	106.00
IUUC-Xtr-132332	Xenopus tropicalis	80.92	1.00e-61	227.00
IUUC-Xma-133186	Xiphophorus maculatus	80.36	7.00e-177	612.00
IUUC-Yli-134500	Yarrowia lipolytica	33.55	4.00e-13	68.90
IUUC-Zma-135391	Zea mays	37.17	3.00e-20	92.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence