iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088869

Ensembl Protein ID

ENSOGAP00000001924.2

UniProt Accession

H0WK54; H0WK54_OTOGA

Genbank Protein ID

ENSOGAP00000001924

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03150863

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000002151.2	ENSOGAT00000002154.2	ENSOGAP00000001924.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	91.93	0.00e+00	744.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	91.93	0.00e+00	744.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	86.38	0.00e+00	733.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	85.94	0.00e+00	723.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MASFTVKAYL LGKEDAAREI RRFSFCFSPE PEAEAEAAGG PGPCQRLLSR VAALFPALRP 60
GGFQAHYRDN LDEDGDLVAF SSDEELTMAM SYVKDDIFRI YIKEKKECRR DHRSPCAQEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCGT TCACCGTGAA GGCCTACCTT CTGGGCAAGG AAGACGCGGC GCGCGAGATC 60
CGCCGCTTCA GCTTCTGCTT CAGCCCAGAG CCTGAGGCAG AAGCCGAGGC CGCAGGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	86.36	6.00e-166	576.00
IUUC-Apl-003897	Anas platyrhynchos	58.17	4.00e-114	404.00
IUUC-Aca-004699	Anolis carolinensis	46.41	2.00e-93	335.00
IUUC-Ame-010982	Astyanax mexicanus	72.17	2.00e-41	163.00
IUUC-Bta-012634	Bos taurus	89.01	0.00e+00	730.00
IUUC-Cel-018660	Caenorhabditis elegans	43.18	2.00e-09	55.50
IUUC-Cja-019684	Callithrix jacchus	90.13	0.00e+00	724.00
IUUC-Cfa-020573	Canis familiaris	78.07	2.00e-129	455.00
IUUC-Cpo-021425	Cavia porcellus	78.52	2.00e-175	608.00
IUUC-Csa-023968	Chlorocebus sabaeus	89.91	0.00e+00	712.00
IUUC-Cho-024596	Choloepus hoffmanni	83.23	5.00e-47	181.00
IUUC-Cin-025557	Ciona intestinalis	36.73	6.00e-10	58.20
IUUC-Csv-025974	Ciona savignyi	25.19	5.00e-13	68.20
IUUC-Dre-028621	Danio rerio	43.36	6.00e-92	331.00
IUUC-Dno-029060	Dasypus novemcinctus	86.58	0.00e+00	708.00
IUUC-Dor-030547	Dipodomys ordii	85.30	6.00e-129	454.00
IUUC-Ete-033201	Echinops telfairi	77.72	1.00e-158	551.00
IUUC-Eca-033456	Equus caballus	88.17	0.00e+00	643.00
IUUC-Eeu-035157	Erinaceus europaeus	82.49	1.00e-168	585.00
IUUC-Fca-035403	Felis catus	86.00	0.00e+00	682.00
IUUC-Fal-036798	Ficedula albicollis	56.48	3.00e-131	461.00
IUUC-Gmo-039619	Gadus morhua	39.86	7.00e-45	174.00
IUUC-Gga-040137	Gallus gallus	57.42	1.00e-129	456.00
IUUC-Gac-042410	Gasterosteus aculeatus	44.12	1.00e-92	333.00
IUUC-Ggo-044690	Gorilla gorilla	92.15	0.00e+00	724.00
IUUC-Hsa-046390	Homo sapiens	91.93	0.00e+00	721.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	91.03	0.00e+00	750.00
IUUC-Lch-049658	Latimeria chalumnae	47.36	2.00e-109	389.00
IUUC-Loc-052589	Lepisosteus oculatus	45.49	4.00e-102	364.00
IUUC-Laf-053746	Loxodonta africana	80.72	0.00e+00	649.00
IUUC-Mcc-055635	Macaca mulatta	88.79	0.00e+00	718.00
IUUC-Meu-056528	Macropus eugenii	49.26	7.00e-96	343.00
IUUC-Mga-059458	Meleagris gallopavo	60.20	2.00e-117	415.00
IUUC-Mmr-061539	Microcebus murinus	87.93	6.00e-136	476.00
IUUC-Mdo-063083	Monodelphis domestica	62.14	2.00e-146	511.00
IUUC-Mmu-063589	Mus musculus	87.28	0.00e+00	725.00
IUUC-Mpu-065727	Mustela putorius furo	87.63	4.00e-176	610.00
IUUC-Mlu-067026	Myotis lucifugus	87.73	0.00e+00	634.00
IUUC-Nle-069356	Nomascus leucogenys	63.94	8.00e-119	420.00
IUUC-Opr-071091	Ochotona princeps	80.18	1.00e-89	323.00
IUUC-Ont-071864	Oreochromis niloticus	45.37	1.00e-96	346.00
IUUC-Oan-073308	Ornithorhynchus anatinus	62.01	2.00e-132	465.00
IUUC-Ocu-074110	Oryctolagus cuniculus	90.29	0.00e+00	732.00
IUUC-Ola-086944	Oryzias latipes	45.25	4.00e-38	150.00
IUUC-Oar-089857	Ovis aries	90.48	0.00e+00	656.00
IUUC-Ptr-091640	Pan troglodytes	92.15	0.00e+00	724.00
IUUC-Pan-092831	Papio anubis	92.38	0.00e+00	742.00
IUUC-Psi-093925	Pelodiscus sinensis	54.73	4.00e-124	437.00
IUUC-Pma-094576	Petromyzon marinus	31.67	2.00e-30	127.00
IUUC-Pfo-097297	Poecilia formosa	43.63	4.00e-85	308.00
IUUC-Pab-098725	Pongo abelii	81.61	0.00e+00	630.00
IUUC-Pca-101106	Procavia capensis	88.79	0.00e+00	701.00
IUUC-Pva-102710	Pteropus vampyrus	84.85	2.00e-176	611.00
IUUC-Rno-105539	Rattus norvegicus	85.71	0.00e+00	723.00
IUUC-Sha-107469	Sarcophilus harrisii	57.72	1.00e-122	432.00
IUUC-Ssc-115526	Sus scrofa	89.46	0.00e+00	709.00
IUUC-Tgu-117194	Taeniopygia guttata	59.84	1.00e-116	412.00
IUUC-Tru-117896	Takifugu rubripes	46.56	5.00e-96	344.00
IUUC-Tni-119943	Tetraodon nigroviridis	45.83	2.00e-85	309.00
IUUC-Ttr-128676	Tursiops truncatus	88.57	0.00e+00	724.00
IUUC-Vda-129812	Verticillium dahliae	37.66	6.00e-07	49.70
IUUC-Vpa-130319	Vicugna pacos	94.00	4.00e-55	207.00
IUUC-Xtr-132907	Xenopus tropicalis	52.81	1.00e-122	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence