iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107443

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01162543

Gene Name

PCGF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017383.1	ENSSHAT00000020665.1	ENSSHAP00000020502.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.00e-06	28.4	18	56
ULD/UDP/UFD/RAWUL	3.80e-23	82.0	134	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           Ca+C   f d + ++ C H f+++C+ ++        ++ +CP C
   Q: 18   CALCGGYFIDATTIVECLHSFCKTCIVRY------LETNKYCPMC 56
           ********999999***************......********** PP

ULD/UDP/UFD/RAWUL

   S: 4    sLeplesnkakddsk.............lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkk 77
           s+e++e  ++++++k             +  ++lrc+a++tV+hl kfl++k++++s+y+v++l+ede+L++++tL++i+yi+ w++
   Q: 134  SIEFYEGVRDREEKKgalengdgdkekkTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRR 220
           555555555555555555555555555699*******************************************************97 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCAL CGGYFIDATT IVECLHSFCK TCIVRYLETN KYCPMCDVQV 60
HKTRPLLSIR SDKTLQDIVY KLVPGLFKDE MKRRRDFYAA YPLTEVPNGS NEDRGEVLEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATCGGA CAACTCGGAT TAAGATCACG GAGCTGAACC CCCATCTCAT GTGTGCCCTC 60
TGTGGGGGGT ACTTCATCGA CGCTACCACC ATCGTAGAAT GTCTGCATTC CTGTAAGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0016604--C:nuclear body
GO:0035102--C:PRC1 complex
GO:0001739--C:sex chromatin
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0009952--P:anterior/posterior pattern specification
GO:0070301--P:cellular response to hydrogen peroxide
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002051	Ailuropoda melanoleuca	94.55	5.00e-120	423.00
IUUC-Aca-004230	Anolis carolinensis	91.86	7.00e-121	426.00
IUUC-Bta-013298	Bos taurus	99.09	1.00e-127	449.00
IUUC-Bol-015090	Brassica oleracea	36.73	7.00e-13	68.20
IUUC-Cja-019674	Callithrix jacchus	97.73	2.00e-126	445.00
IUUC-Cfa-020865	Canis familiaris	87.95	5.00e-111	393.00
IUUC-Cpo-022149	Cavia porcellus	97.27	6.00e-126	443.00
IUUC-Csa-024153	Chlorocebus sabaeus	98.18	6.00e-127	446.00
IUUC-Dno-029941	Dasypus novemcinctus	95.00	3.00e-121	427.00
IUUC-Dor-030557	Dipodomys ordii	99.09	3.00e-128	451.00
IUUC-Eca-033878	Equus caballus	97.73	2.00e-124	438.00
IUUC-Eeu-035039	Erinaceus europaeus	89.55	3.00e-113	400.00
IUUC-Fca-036531	Felis catus	97.42	1.00e-111	395.00
IUUC-Gga-040311	Gallus gallus	84.55	1.00e-110	392.00
IUUC-Ggo-045132	Gorilla gorilla	98.18	6.00e-127	446.00
IUUC-Hsa-045703	Homo sapiens	91.32	4.00e-127	447.00
IUUC-Itr-048008	Ictidomys tridecemlineatus	99.09	1.00e-127	449.00
IUUC-Laf-053589	Loxodonta africana	98.64	7.00e-129	452.00
IUUC-Mcc-055228	Macaca mulatta	98.18	7.00e-127	446.00
IUUC-Meu-056268	Macropus eugenii	82.27	1.00e-101	362.00
IUUC-Mmr-060605	Microcebus murinus	98.64	2.00e-127	448.00
IUUC-Mdo-061947	Monodelphis domestica	98.18	2.00e-126	445.00
IUUC-Mmu-063845	Mus musculus	97.27	9.00e-126	442.00
IUUC-Mpu-066061	Mustela putorius furo	97.73	4.00e-126	443.00
IUUC-Mlu-067426	Myotis lucifugus	90.39	1.00e-117	416.00
IUUC-Nle-069772	Nomascus leucogenys	98.18	5.00e-127	446.00
IUUC-Ocu-074159	Oryctolagus cuniculus	86.40	1.00e-111	396.00
IUUC-Oga-088514	Otolemur garnettii	98.64	3.00e-127	447.00
IUUC-Oar-090406	Ovis aries	77.98	4.00e-135	473.00
IUUC-Ptr-091467	Pan troglodytes	90.91	2.00e-126	445.00
IUUC-Psi-093492	Pelodiscus sinensis	70.62	4.00e-129	454.00
IUUC-Pab-098045	Pongo abelii	91.71	4.00e-113	400.00
IUUC-Pca-100551	Procavia capensis	98.18	3.00e-127	447.00
IUUC-Pva-102686	Pteropus vampyrus	98.64	3.00e-127	447.00
IUUC-Rno-105679	Rattus norvegicus	97.27	5.00e-126	443.00
IUUC-Smo-109158	Selaginella moellendorffii	47.83	2.00e-11	63.90
IUUC-Ssc-115591	Sus scrofa	71.12	2.00e-121	427.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence