iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042020

UUCD1 version

UUC-GaA-00849

Ensembl Protein ID

ENSGACP00000021744.1

UniProt Accession

G3PVV5; G3PVV5_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000016463.1	ENSGACT00000021785.1	ENSGACP00000021744.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.60e-135	449.9	644	975

Active Site

Position(s)	Description	Evidence
945	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++ lk+rl++ef+ E+gld+gGv+re+++llske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+lld 
   Q: 644  PDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVFHGKLLDG 732
           57899************************************************************************************ PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
           ++ ++fyk++lgk++sl+d+e+vd+e+y+slk+i+en   d +e  ldl+f+++e+++g+t++++Lkp+G+++ VtneNk+eY++lv++
   Q: 733  FFIRPFYKMMLGKQISLKDMESVDSEYYNSLKWILEN---DPTE--LDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNENKKEYIDLVIQ 816
           ***********************************99...6666..7****************************************** PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +++++q++af eGf+e+i ++l+++F+e+elell+cG  ++dv+d++++t yk+gy +++p+iqwFw+v+  +++e+r ++LqFv
   Q: 817  WRFVNRVQKQMNAFLEGFTELILIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKVVLLMDAEKRIRLLQFV 905
           ***************************************************************************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           Tg+sr+P++Gfael     p+lf+i++++++++lP+++TCfn+L+LP+Y+s e l+ekLl+A+e+++gFe
   Q: 906  TGTSRVPMNGFAELYgsngPQLFTIEQWGTPEKLPRAHTCFNRLDLPTYDSFEDLREKLLMAVENAQGFE 975
           *********************************************************************8 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MAANYEPIYG LSEDEHETRV LRVKVIAGMD LAKKDIIGAS DPYVKLSLYV AEENKELGLV 60
QTKTIKKTLN PKWNEEFFFR VCPQNHRLLF EVFDENRLTR DDFLGQVDVP LSHLPTEDPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCGA ATTACGAGCC GATCTATGGA CTTTCAGAAG ATGAGGTAAG CTATAATTTG 60
AACACGGCTC TGCTACACGG ATGTCAGTCA TGATGTGTCT CTCGCGGGGG GGGGGGCGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

PRINTS

PR00360--C2DOMAIN

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	78.44	0.00e+00	1391.00
IUUC-Apl-003893	Anas platyrhynchos	79.71	0.00e+00	1434.00
IUUC-Aca-004744	Anolis carolinensis	76.43	0.00e+00	1380.00
IUUC-Ago-007742	Ashbya gossypii	48.40	1.00e-161	563.00
IUUC-Acl-008273	Aspergillus clavatus	50.33	7.00e-164	571.00
IUUC-Afl-008713	Aspergillus flavus	50.00	6.00e-163	567.00
IUUC-Afu-009103	Aspergillus fumigatus	50.50	4.00e-165	575.00
IUUC-Ani-009259	Aspergillus nidulans	49.84	8.00e-164	570.00
IUUC-Ang-009738	Aspergillus niger	49.75	2.00e-162	566.00
IUUC-Aor-010053	Aspergillus oryzae	57.72	2.00e-100	358.00
IUUC-Ate-010529	Aspergillus terreus	50.00	2.00e-164	572.00
IUUC-Ame-010810	Astyanax mexicanus	90.84	0.00e+00	1082.00
IUUC-Bgr-012148	Blumeria graminis	47.66	7.00e-154	537.00
IUUC-Bta-012679	Bos taurus	78.87	0.00e+00	1297.00
IUUC-Bci-013785	Botrytis cinerea	47.91	8.00e-157	547.00
IUUC-Cel-018564	Caenorhabditis elegans	51.08	3.00e-178	618.00
IUUC-Cja-018732	Callithrix jacchus	79.37	0.00e+00	1477.00
IUUC-Cfa-021226	Canis familiaris	80.04	0.00e+00	1467.00
IUUC-Cpo-021671	Cavia porcellus	78.72	0.00e+00	1437.00
IUUC-Csa-023344	Chlorocebus sabaeus	78.51	0.00e+00	1461.00
IUUC-Cho-024832	Choloepus hoffmanni	94.89	0.00e+00	716.00
IUUC-Csv-026098	Ciona savignyi	58.00	0.00e+00	646.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	47.49	6.00e-154	538.00
IUUC-Cne-026849	Cryptococcus neoformans	49.25	2.00e-160	559.00
IUUC-Dre-027770	Danio rerio	84.25	0.00e+00	1544.00
IUUC-Dno-029466	Dasypus novemcinctus	80.00	0.00e+00	1477.00
IUUC-Dor-030138	Dipodomys ordii	76.08	0.00e+00	1338.00
IUUC-Dse-031241	Dothistroma septosporum	48.83	3.00e-158	552.00
IUUC-Ete-033145	Echinops telfairi	74.57	0.00e+00	1060.00
IUUC-Eca-033445	Equus caballus	79.55	0.00e+00	1289.00
IUUC-Eeu-035247	Erinaceus europaeus	78.45	0.00e+00	1155.00
IUUC-Fca-035489	Felis catus	77.09	0.00e+00	1241.00
IUUC-Fal-037604	Ficedula albicollis	77.16	0.00e+00	1451.00
IUUC-Fox-037774	Fusarium oxysporum	47.45	7.00e-156	544.00
IUUC-Fso-038393	Fusarium solani	46.99	1.00e-154	540.00
IUUC-Gmo-039674	Gadus morhua	85.23	0.00e+00	1555.00
IUUC-Ggr-040107	Gaeumannomyces graminis	48.33	6.00e-155	541.00
IUUC-Gga-040703	Gallus gallus	79.74	0.00e+00	1480.00
IUUC-Ggo-045332	Gorilla gorilla	78.96	0.00e+00	1407.00
IUUC-Hsa-045968	Homo sapiens	79.96	0.00e+00	1474.00
IUUC-Kpa-049273	Komagataella pastoris	49.24	4.00e-162	565.00
IUUC-Lch-050443	Latimeria chalumnae	79.98	0.00e+00	1317.00
IUUC-Loc-052662	Lepisosteus oculatus	82.42	0.00e+00	1490.00
IUUC-Laf-053850	Loxodonta africana	78.90	0.00e+00	1449.00
IUUC-Mcc-055821	Macaca mulatta	80.04	0.00e+00	1455.00
IUUC-Meu-056712	Macropus eugenii	61.31	7.00e-160	558.00
IUUC-Mor-057097	Magnaporthe oryzae	47.03	1.00e-156	546.00
IUUC-Mvi-060395	Microbotryum violaceum	54.73	1.00e-152	533.00
IUUC-Mmr-060798	Microcebus murinus	76.29	0.00e+00	1360.00
IUUC-Mdo-062173	Monodelphis domestica	78.34	0.00e+00	1476.00
IUUC-Mmu-064136	Mus musculus	79.55	0.00e+00	1461.00
IUUC-Mpu-066765	Mustela putorius furo	79.86	0.00e+00	1450.00
IUUC-Mlu-067565	Myotis lucifugus	78.73	0.00e+00	1290.00
IUUC-Nfi-068427	Neosartorya fischeri	50.67	3.00e-165	575.00
IUUC-Ncr-068918	Neurospora crassa	48.58	1.00e-156	547.00
IUUC-Nle-069070	Nomascus leucogenys	77.32	0.00e+00	1409.00
IUUC-Opr-071044	Ochotona princeps	86.96	0.00e+00	1073.00
IUUC-Ont-072044	Oreochromis niloticus	89.03	0.00e+00	1707.00
IUUC-Oan-073032	Ornithorhynchus anatinus	75.79	0.00e+00	1179.00
IUUC-Ocu-074160	Oryctolagus cuniculus	77.84	0.00e+00	1413.00
IUUC-Ola-087467	Oryzias latipes	90.36	0.00e+00	1651.00
IUUC-Oga-088460	Otolemur garnettii	78.09	0.00e+00	1286.00
IUUC-Oar-090198	Ovis aries	79.42	0.00e+00	1437.00
IUUC-Ptr-090939	Pan troglodytes	79.96	0.00e+00	1474.00
IUUC-Pan-092284	Papio anubis	80.16	0.00e+00	1477.00
IUUC-Psi-093645	Pelodiscus sinensis	79.55	0.00e+00	1483.00
IUUC-Pma-094364	Petromyzon marinus	82.95	0.00e+00	838.00
IUUC-Pno-095118	Phaeosphaeria nodorum	48.41	1.00e-159	557.00
IUUC-Pfo-096768	Poecilia formosa	97.05	0.00e+00	1004.00
IUUC-Pab-098088	Pongo abelii	79.86	0.00e+00	1461.00
IUUC-Pca-100714	Procavia capensis	71.37	0.00e+00	973.00
IUUC-Pva-102354	Pteropus vampyrus	78.47	0.00e+00	1387.00
IUUC-Pgr-103620	Puccinia graminis	53.32	5.00e-148	518.00
IUUC-Ptt-103806	Puccinia triticina	53.86	1.00e-124	440.00
IUUC-Pte-104016	Pyrenophora teres	48.34	2.00e-159	556.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	48.34	2.00e-159	556.00
IUUC-Rno-105318	Rattus norvegicus	78.80	0.00e+00	1425.00
IUUC-Sce-106289	Saccharomyces cerevisiae	49.50	1.00e-163	570.00
IUUC-Sha-107482	Sarcophilus harrisii	79.48	0.00e+00	1319.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	48.41	8.00e-158	550.00
IUUC-Ssc-115950	Sus scrofa	63.14	0.00e+00	1034.00
IUUC-Tgu-117130	Taeniopygia guttata	79.46	0.00e+00	1462.00
IUUC-Tru-118610	Takifugu rubripes	92.06	0.00e+00	1716.00
IUUC-Tsy-119492	Tarsius syrichta	75.79	0.00e+00	1318.00
IUUC-Tni-120113	Tetraodon nigroviridis	86.09	0.00e+00	1556.00
IUUC-Tre-122203	Trichoderma reesei	47.16	3.00e-152	532.00
IUUC-Tvi-122595	Trichoderma virens	47.68	1.00e-155	543.00
IUUC-Ttr-128235	Tursiops truncatus	89.93	0.00e+00	1006.00
IUUC-Vda-129753	Verticillium dahliae	47.32	4.00e-154	538.00
IUUC-Xtr-132859	Xenopus tropicalis	79.85	0.00e+00	1455.00
IUUC-Xma-133797	Xiphophorus maculatus	91.97	0.00e+00	1695.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence