iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094364

UUCD1 version

UUC-PeM-00422

Ensembl Protein ID

ENSPMAP00000005985.1

UniProt Accession

S4RL99; S4RL99_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000005359.1	ENSPMAT00000006013.1	ENSPMAP00000005985.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.90e-132	439.6	160	491

Active Site

Position(s)	Description	Evidence
461	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           + lk+rl++ef gE+gld+gGv+re+++l+ske++np++glf+ys++d++tlq+np sgl+n+ehl++F+f+Gr+ g+a+++g+lld +
   Q: 160  DLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPISGLCNEEHLSYFTFIGRVAGMAVFHGKLLDGF 248
           56899************************************************************************************ PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetk.eeeLkpgGenipVtneNkeeYvklvve 179
           + ++fyk++l+k+++l+d+e+vd+e+y+sl++i+en   d   ++ldl+f+++ee +g+++  +eLkp+G++i VtneNk+eY++lv++
   Q: 249  FIRPFYKMMLQKPITLNDMESVDSEYYNSLMWILEN---DP--ADLDLRFCIDEEMFGQQThLVELKPNGSEILVTNENKKEYIELVIQ 332
           **********************************99...44..558*********9876551689************************ PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ e++++q++af eGf+e+ip++l+++F+e+elell+cG  ++dv+d++++t yk+ y +++p+iqwFw+++  ++ e+r ++LqFv
   Q: 333  WRFVERVQKQINAFMEGFSELIPMDLIKIFDENELELLMCGLGDVDVNDWRQHTIYKNSYCANHPVIQWFWKAVLLMDGEKRIRLLQFV 421
           ***************************************************************************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           Tg+sr+P++Gfael     p+lf+i+ +++ ++lP+++TCfn+L+LP+Y+s + l+ekL +Aie+++gFe
   Q: 422  TGTSRVPMNGFAELYgsngPQLFTIEMWSTSEKLPRAHTCFNRLDLPPYESFDDLREKLNIAIENAQGFE 491
           *********************************************************************8 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

SPQASPYGSP KQKHKGCPGF SFLPAGWEMR FAPNGRPFFI DHNNRTTTWS HISLSTMLHP 60
RFSLFPLPHP GWEERTHSDG RTFYIDHNTK NTQWEDPRLQ NPAITGPAVP YSRDYKQKYD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGCCGCAGG CGTCTCCGTA CGGCTCCCCC AAGCAGAAGC ACAAGGGCTG CCCTGGCTTC 60
AGCTTCCTGC CGGCCGGCTG GGAGATGAGG TTCGCCCCCA ACGGTCGCCC ATTCTTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00632--HECT
PF00397--WW

SMART

SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	42.46	7.00e-72	266.00
IUUC-Aml-001314	Ailuropoda melanoleuca	83.12	0.00e+00	833.00
IUUC-Atr-002582	Amborella trichopoda	44.90	2.00e-86	314.00
IUUC-Apl-003893	Anas platyrhynchos	83.12	0.00e+00	830.00
IUUC-Aca-004744	Anolis carolinensis	79.58	0.00e+00	785.00
IUUC-Aly-006157	Arabidopsis lyrata	44.96	2.00e-88	321.00
IUUC-Ath-007472	Arabidopsis thaliana	44.27	1.00e-86	315.00
IUUC-Ago-007742	Ashbya gossypii	51.87	9.00e-142	496.00
IUUC-Acl-008273	Aspergillus clavatus	51.84	1.00e-142	498.00
IUUC-Afl-008713	Aspergillus flavus	52.05	3.00e-142	497.00
IUUC-Afu-009103	Aspergillus fumigatus	52.05	8.00e-143	499.00
IUUC-Ani-009259	Aspergillus nidulans	52.87	3.00e-143	500.00
IUUC-Ang-009738	Aspergillus niger	52.66	7.00e-143	499.00
IUUC-Aor-010053	Aspergillus oryzae	57.53	1.00e-99	354.00
IUUC-Ate-010529	Aspergillus terreus	52.05	3.00e-142	497.00
IUUC-Ame-010810	Astyanax mexicanus	82.71	0.00e+00	830.00
IUUC-Bgr-012148	Blumeria graminis	49.80	4.00e-135	474.00
IUUC-Bta-012679	Bos taurus	83.12	0.00e+00	835.00
IUUC-Bci-013785	Botrytis cinerea	49.90	1.00e-136	479.00
IUUC-Bdi-014884	Brachypodium distachyon	45.94	3.00e-87	317.00
IUUC-Bol-016533	Brassica oleracea	48.72	1.00e-69	254.00
IUUC-Bra-016726	Brassica rapa	44.72	2.00e-89	324.00
IUUC-Cel-018564	Caenorhabditis elegans	57.83	1.00e-162	565.00
IUUC-Cja-018732	Callithrix jacchus	83.12	0.00e+00	834.00
IUUC-Cfa-021226	Canis familiaris	82.92	0.00e+00	832.00
IUUC-Cpo-021671	Cavia porcellus	83.12	0.00e+00	834.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	44.16	5.00e-92	329.00
IUUC-Csa-023344	Chlorocebus sabaeus	79.92	0.00e+00	821.00
IUUC-Cho-024832	Choloepus hoffmanni	87.25	0.00e+00	650.00
IUUC-Cin-025157	Ciona intestinalis	72.35	0.00e+00	725.00
IUUC-Csv-026098	Ciona savignyi	66.59	3.00e-174	603.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	50.70	6.00e-139	486.00
IUUC-Cne-026849	Cryptococcus neoformans	50.72	7.00e-136	476.00
IUUC-Cme-027267	Cyanidioschyzon merolae	40.99	3.00e-75	276.00
IUUC-Dre-027770	Danio rerio	81.02	0.00e+00	826.00
IUUC-Dno-029466	Dasypus novemcinctus	83.12	0.00e+00	835.00
IUUC-Dor-030138	Dipodomys ordii	81.46	0.00e+00	815.00
IUUC-Dse-031241	Dothistroma septosporum	52.13	6.00e-142	496.00
IUUC-Dme-032166	Drosophila melanogaster	67.85	0.00e+00	690.00
IUUC-Ete-033145	Echinops telfairi	78.12	0.00e+00	777.00
IUUC-Eca-033445	Equus caballus	83.12	0.00e+00	833.00
IUUC-Eeu-035247	Erinaceus europaeus	83.12	0.00e+00	832.00
IUUC-Fca-035489	Felis catus	79.18	0.00e+00	794.00
IUUC-Fal-037604	Ficedula albicollis	79.05	0.00e+00	817.00
IUUC-Fox-037774	Fusarium oxysporum	50.20	1.00e-139	489.00
IUUC-Fso-038393	Fusarium solani	50.90	1.00e-138	485.00
IUUC-Gmo-039674	Gadus morhua	82.05	0.00e+00	813.00
IUUC-Ggr-040107	Gaeumannomyces graminis	50.30	6.00e-139	486.00
IUUC-Gga-041276	Gallus gallus	83.33	0.00e+00	833.00
IUUC-Gac-042020	Gasterosteus aculeatus	82.25	0.00e+00	815.00
IUUC-Gma-044216	Glycine max	45.41	5.00e-87	316.00
IUUC-Ggo-045332	Gorilla gorilla	83.12	0.00e+00	831.00
IUUC-Hsa-045968	Homo sapiens	83.12	0.00e+00	833.00
IUUC-Hvu-047697	Hordeum vulgare	46.19	1.00e-87	318.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	77.08	0.00e+00	777.00
IUUC-Kpa-049273	Komagataella pastoris	52.16	4.00e-142	497.00
IUUC-Lch-050443	Latimeria chalumnae	82.50	0.00e+00	823.00
IUUC-Lpe-051550	Leersia perrieri	45.43	4.00e-87	317.00
IUUC-Loc-052662	Lepisosteus oculatus	82.47	0.00e+00	807.00
IUUC-Lma-053159	Leptosphaeria maculans	43.27	3.00e-87	317.00
IUUC-Laf-053850	Loxodonta africana	83.12	0.00e+00	833.00
IUUC-Mcc-055821	Macaca mulatta	83.12	0.00e+00	833.00
IUUC-Meu-056897	Macropus eugenii	84.03	1.00e-146	512.00
IUUC-Mor-057097	Magnaporthe oryzae	50.70	1.00e-139	489.00
IUUC-Mpo-057442	Magnaporthe poae	50.50	1.00e-138	486.00
IUUC-Mtr-057633	Medicago truncatula	46.17	8.00e-89	322.00
IUUC-Mla-058996	Melampsora laricipopulina	53.28	4.00e-143	500.00
IUUC-Mga-059362	Meleagris gallopavo	80.58	0.00e+00	800.00
IUUC-Mvi-060395	Microbotryum violaceum	52.58	1.00e-141	495.00
IUUC-Mmr-061061	Microcebus murinus	80.67	0.00e+00	815.00
IUUC-Mdo-062173	Monodelphis domestica	79.76	0.00e+00	820.00
IUUC-Mmu-064136	Mus musculus	83.12	0.00e+00	836.00
IUUC-Mac-065557	Musa acuminata	43.91	2.00e-82	301.00
IUUC-Mpu-066765	Mustela putorius furo	83.12	0.00e+00	833.00
IUUC-Mlu-067565	Myotis lucifugus	83.12	0.00e+00	833.00
IUUC-Nfi-068427	Neosartorya fischeri	52.05	5.00e-143	499.00
IUUC-Ncr-068918	Neurospora crassa	52.36	2.00e-141	494.00
IUUC-Nle-069070	Nomascus leucogenys	81.29	0.00e+00	812.00
IUUC-Opr-071044	Ochotona princeps	83.12	0.00e+00	830.00
IUUC-Ont-072044	Oreochromis niloticus	82.74	0.00e+00	836.00
IUUC-Oan-073019	Ornithorhynchus anatinus	80.58	0.00e+00	800.00
IUUC-Ocu-074160	Oryctolagus cuniculus	83.12	0.00e+00	833.00
IUUC-Oba-075757	Oryza barthii	44.92	5.00e-86	313.00
IUUC-Obr-076553	Oryza brachyantha	45.18	2.00e-86	314.00
IUUC-Ogl-077520	Oryza glaberrima	44.92	6.00e-86	312.00
IUUC-Ogu-078278	Oryza glumaepatula	44.92	5.00e-86	313.00
IUUC-Oin-079767	Oryza indica	44.92	6.00e-86	312.00
IUUC-Olo-080380	Oryza longistaminata	44.47	2.00e-84	307.00
IUUC-Ome-081925	Oryza meridionalis	44.47	3.00e-84	307.00
IUUC-Oni-082619	Oryza nivara	44.92	6.00e-86	312.00
IUUC-Opu-083428	Oryza punctata	43.18	2.00e-85	311.00
IUUC-Oru-084501	Oryza rufipogon	44.92	6.00e-86	312.00
IUUC-Osa-086251	Oryza sativa	44.01	3.00e-86	311.00
IUUC-Ola-087467	Oryzias latipes	81.00	0.00e+00	835.00
IUUC-Olu-087813	Ostreococcus lucimarinus	40.10	3.00e-73	267.00
IUUC-Oga-088460	Otolemur garnettii	83.12	0.00e+00	831.00
IUUC-Oar-090198	Ovis aries	83.12	0.00e+00	836.00
IUUC-Ptr-090939	Pan troglodytes	83.12	0.00e+00	833.00
IUUC-Pan-092284	Papio anubis	83.12	0.00e+00	834.00
IUUC-Psi-093645	Pelodiscus sinensis	82.71	0.00e+00	830.00
IUUC-Pno-095118	Phaeosphaeria nodorum	52.57	2.00e-144	504.00
IUUC-Ppa-095834	Physcomitrella patens	43.30	1.00e-85	311.00
IUUC-Pfo-096768	Poecilia formosa	82.12	0.00e+00	815.00
IUUC-Pab-098088	Pongo abelii	83.12	0.00e+00	833.00
IUUC-Pop-099468	Populus trichocarpa	45.66	3.00e-86	313.00
IUUC-Pca-100568	Procavia capensis	74.80	0.00e+00	770.00
IUUC-Ppe-101641	Prunus persica	45.15	7.00e-88	319.00
IUUC-Pva-102354	Pteropus vampyrus	83.12	0.00e+00	833.00
IUUC-Pgr-103620	Puccinia graminis	52.53	3.00e-141	494.00
IUUC-Ptt-103806	Puccinia triticina	52.62	3.00e-116	411.00
IUUC-Pte-104016	Pyrenophora teres	52.77	9.00e-144	502.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	52.77	9.00e-144	502.00
IUUC-Rno-105318	Rattus norvegicus	83.12	0.00e+00	834.00
IUUC-Sce-106289	Saccharomyces cerevisiae	52.46	8.00e-145	506.00
IUUC-Sha-107482	Sarcophilus harrisii	82.99	0.00e+00	835.00
IUUC-Sja-107786	Schizosaccharomyces japonicus	52.33	3.00e-142	497.00
IUUC-Spo-108171	Schizosaccharomyces pombe	52.75	6.00e-145	506.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	49.90	6.00e-137	479.00
IUUC-Smo-109640	Selaginella moellendorffii	43.26	4.00e-87	317.00
IUUC-Sit-110149	Setaria italica	44.02	9.00e-89	322.00
IUUC-Sly-111706	Solanum lycopersicum	45.92	3.00e-89	323.00
IUUC-Stu-112582	Solanum tuberosum	35.16	2.00e-53	202.00
IUUC-Sbi-113794	Sorghum bicolor	44.25	2.00e-88	321.00
IUUC-Sre-114929	Sporisorium reilianum	51.65	3.00e-139	488.00
IUUC-Ssc-115950	Sus scrofa	79.17	0.00e+00	788.00
IUUC-Tgu-117130	Taeniopygia guttata	82.34	0.00e+00	832.00
IUUC-Tru-118610	Takifugu rubripes	82.74	0.00e+00	835.00
IUUC-Tsy-119492	Tarsius syrichta	82.92	0.00e+00	825.00
IUUC-Tni-119993	Tetraodon nigroviridis	79.75	0.00e+00	790.00
IUUC-Tca-121479	Theobroma cacao	44.96	3.00e-88	320.00
IUUC-Tre-122203	Trichoderma reesei	51.00	1.00e-139	489.00
IUUC-Tvi-122595	Trichoderma virens	50.80	7.00e-139	486.00
IUUC-Tae-125214	Triticum aestivum	46.19	3.00e-88	319.00
IUUC-Tme-126897	Tuber melanosporum	51.03	3.00e-136	477.00
IUUC-Tbe-127408	Tupaia belangeri	75.59	0.00e+00	713.00
IUUC-Ttr-128235	Tursiops truncatus	82.71	0.00e+00	828.00
IUUC-Uma-129332	Ustilago maydis	51.03	1.00e-132	465.00
IUUC-Vda-129753	Verticillium dahliae	49.70	6.00e-137	479.00
IUUC-Vpa-130503	Vicugna pacos	80.46	0.00e+00	782.00
IUUC-Vvi-131078	Vitis vinifera	45.41	3.00e-86	313.00
IUUC-Xtr-132859	Xenopus tropicalis	81.93	0.00e+00	833.00
IUUC-Xma-133797	Xiphophorus maculatus	82.29	0.00e+00	820.00
IUUC-Yli-134668	Yarrowia lipolytica	50.20	4.00e-142	497.00
IUUC-Zma-135595	Zea mays	43.38	1.00e-88	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence