iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115804

Ensembl Protein ID

ENSSSCP00000023381.1

UniProt Accession

I3LH37; I3LH37_PIG

Genbank Protein ID

ENSSSCP00000023381

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP565444

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000027529.1	ENSSSCT00000023790.1	ENSSSCP00000023381.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	28.96	3.00e-64	243.00	IUUC-Dme-031819
E3 activity/RING/RING	88.10	0.00e+00	1048.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MHKTISQDLS QVPRIEIKSV MEDSTILSNW TVGNKQKMKY DFSCELYRMS TYSAFPAGVP 60
VSERSLARAG FYYTGVNDKV KCFCCGLMLD NWKQGDNPME KHKQLYPSCS FVQNLVSVTC 120

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Nucleotide Sequence
(Fasta)

AGTTCAGCCC GCGTCGTTGC TCCCGGGACT GTGGAGGCTC CTGGTGGCAC TGCTGTTTCG 60
TGTTGGACGC GTCTGCCCTG TGGTGAGTGC AGGTCCTTCC GGACCCAGGC CTCGCGGGGC 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0043027--F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:1990001--P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070266--P:necroptotic process
GO:0060546--P:negative regulation of necroptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	84.94	0.00e+00	1055.00
IUUC-Atr-002499	Amborella trichopoda	44.64	3.00e-12	65.50
IUUC-Apl-003549	Anas platyrhynchos	71.45	0.00e+00	835.00
IUUC-Aca-004515	Anolis carolinensis	68.12	0.00e+00	787.00
IUUC-Aly-006460	Arabidopsis lyrata	37.04	2.00e-09	55.80
IUUC-Ath-007365	Arabidopsis thaliana	43.48	7.00e-08	55.50
IUUC-Acl-008330	Aspergillus clavatus	29.07	8.00e-15	75.50
IUUC-Afl-008648	Aspergillus flavus	31.79	2.00e-15	77.80
IUUC-Afu-008813	Aspergillus fumigatus	30.95	4.00e-14	73.60
IUUC-Ani-009424	Aspergillus nidulans	31.98	1.00e-14	74.70
IUUC-Ang-009667	Aspergillus niger	29.19	7.00e-13	69.30
IUUC-Ate-010501	Aspergillus terreus	31.90	5.00e-15	76.30
IUUC-Ame-011877	Astyanax mexicanus	54.81	0.00e+00	644.00
IUUC-Bgr-012051	Blumeria graminis	33.76	2.00e-12	67.40
IUUC-Bta-012450	Bos taurus	90.43	0.00e+00	993.00
IUUC-Bci-013905	Botrytis cinerea	34.78	2.00e-16	80.90
IUUC-Bol-015478	Brassica oleracea	33.62	2.00e-10	63.50
IUUC-Bra-017001	Brassica rapa	34.48	1.00e-10	64.70
IUUC-Cel-018418	Caenorhabditis elegans	40.00	2.00e-08	53.50
IUUC-Cja-018895	Callithrix jacchus	86.84	0.00e+00	1032.00
IUUC-Cfa-020419	Canis familiaris	86.96	0.00e+00	1071.00
IUUC-Cpo-022048	Cavia porcellus	85.37	0.00e+00	1040.00
IUUC-Csa-024159	Chlorocebus sabaeus	80.17	0.00e+00	939.00
IUUC-Cho-024277	Choloepus hoffmanni	82.64	0.00e+00	983.00
IUUC-Csv-026182	Ciona savignyi	31.21	1.00e-66	247.00
IUUC-Cgl-026472	Colletotrichum gloeosporioides	36.20	4.00e-17	83.60
IUUC-Dre-028647	Danio rerio	55.07	0.00e+00	632.00
IUUC-Dno-029509	Dasypus novemcinctus	80.00	0.00e+00	941.00
IUUC-Dor-030796	Dipodomys ordii	71.18	2.00e-95	343.00
IUUC-Dme-031819	Drosophila melanogaster	29.44	2.00e-67	249.00
IUUC-Ete-032768	Echinops telfairi	66.04	0.00e+00	723.00
IUUC-Eca-033393	Equus caballus	91.51	0.00e+00	1085.00
IUUC-Eeu-035114	Erinaceus europaeus	83.47	0.00e+00	986.00
IUUC-Fca-036034	Felis catus	85.53	0.00e+00	1030.00
IUUC-Fal-037656	Ficedula albicollis	69.11	0.00e+00	830.00
IUUC-Fox-037889	Fusarium oxysporum	31.03	2.00e-14	74.70
IUUC-Fso-038452	Fusarium solani	30.65	1.00e-12	68.60
IUUC-Gmo-038477	Gadus morhua	54.39	2.00e-176	612.00
IUUC-Ggr-039891	Gaeumannomyces graminis	33.54	4.00e-15	76.60
IUUC-Gga-040601	Gallus gallus	69.93	0.00e+00	842.00
IUUC-Gac-041467	Gasterosteus aculeatus	55.13	6.00e-177	613.00
IUUC-Ggo-044857	Gorilla gorilla	87.78	0.00e+00	1051.00
IUUC-Hsa-045769	Homo sapiens	88.10	0.00e+00	1054.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	86.31	0.00e+00	1065.00
IUUC-Lch-050259	Latimeria chalumnae	60.62	0.00e+00	720.00
IUUC-Lpe-051271	Leersia perrieri	38.30	5.00e-07	52.40
IUUC-Loc-052169	Lepisosteus oculatus	53.57	2.00e-168	585.00
IUUC-Lma-052958	Leptosphaeria maculans	33.77	6.00e-11	62.80
IUUC-Laf-053449	Loxodonta africana	84.78	0.00e+00	1010.00
IUUC-Mcc-055282	Macaca mulatta	80.66	0.00e+00	945.00
IUUC-Meu-056241	Macropus eugenii	66.02	0.00e+00	708.00
IUUC-Mor-057252	Magnaporthe oryzae	34.38	2.00e-16	80.90
IUUC-Mtr-058211	Medicago truncatula	35.85	2.00e-09	60.50
IUUC-Mga-059947	Meleagris gallopavo	69.54	0.00e+00	845.00
IUUC-Mvi-060388	Microbotryum violaceum	24.50	3.00e-07	50.10
IUUC-Mmr-060719	Microcebus murinus	74.59	0.00e+00	873.00
IUUC-Mdo-062352	Monodelphis domestica	76.12	0.00e+00	919.00
IUUC-Mmu-064340	Mus musculus	81.25	0.00e+00	976.00
IUUC-Mac-065489	Musa acuminata	36.73	3.00e-08	52.40
IUUC-Mpu-065890	Mustela putorius furo	85.34	0.00e+00	961.00
IUUC-Mlu-068077	Myotis lucifugus	88.63	0.00e+00	1084.00
IUUC-Nfi-068591	Neosartorya fischeri	29.07	4.00e-14	73.60
IUUC-Nle-070081	Nomascus leucogenys	86.50	0.00e+00	1054.00
IUUC-Opr-070561	Ochotona princeps	81.32	0.00e+00	972.00
IUUC-Ont-071776	Oreochromis niloticus	54.16	0.00e+00	629.00
IUUC-Oan-073604	Ornithorhynchus anatinus	73.66	0.00e+00	883.00
IUUC-Ocu-073963	Oryctolagus cuniculus	87.02	0.00e+00	1018.00
IUUC-Oba-075143	Oryza barthii	40.43	3.00e-07	53.10
IUUC-Ogu-078452	Oryza glumaepatula	45.45	4.00e-07	48.90
IUUC-Ome-081491	Oryza meridionalis	40.43	3.00e-07	53.10
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.00
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Osa-085816	Oryza sativa	40.43	6.00e-08	51.20
IUUC-Ola-086446	Oryzias latipes	52.48	2.00e-171	595.00
IUUC-Oga-087976	Otolemur garnettii	87.48	0.00e+00	1049.00
IUUC-Oar-090097	Ovis aries	88.94	0.00e+00	1105.00
IUUC-Ptr-091137	Pan troglodytes	88.26	0.00e+00	1055.00
IUUC-Pan-092673	Papio anubis	88.75	0.00e+00	1062.00
IUUC-Psi-092992	Pelodiscus sinensis	70.31	0.00e+00	838.00
IUUC-Pma-094277	Petromyzon marinus	38.22	1.00e-113	403.00
IUUC-Pno-094971	Phaeosphaeria nodorum	32.45	1.00e-10	60.80
IUUC-Ppa-095167	Physcomitrella patens	42.86	2.00e-11	63.20
IUUC-Pfo-096790	Poecilia formosa	53.25	1.00e-176	612.00
IUUC-Pab-098734	Pongo abelii	89.68	0.00e+00	1042.00
IUUC-Pop-098944	Populus trichocarpa	42.59	5.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	73.81	2.00e-172	598.00
IUUC-Ppe-101533	Prunus persica	43.48	1.00e-07	54.30
IUUC-Pva-102788	Pteropus vampyrus	88.75	0.00e+00	1060.00
IUUC-Pte-104098	Pyrenophora teres	33.75	9.00e-15	74.30
IUUC-Pyt-104561	Pyrenophora triticirepentis	33.75	1.00e-14	74.30
IUUC-Rno-105026	Rattus norvegicus	80.37	0.00e+00	951.00
IUUC-Sha-107229	Sarcophilus harrisii	69.71	0.00e+00	846.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	32.45	2.00e-14	74.30
IUUC-Spo-108317	Schizosaccharomyces pombe	29.51	1.00e-15	78.60
IUUC-Sar-113239	Sorex araneus	67.99	0.00e+00	774.00
IUUC-Tgu-116931	Taeniopygia guttata	69.61	0.00e+00	846.00
IUUC-Tru-117620	Takifugu rubripes	54.28	2.00e-179	622.00
IUUC-Tsy-118958	Tarsius syrichta	68.44	8.00e-148	516.00
IUUC-Tni-119683	Tetraodon nigroviridis	53.39	6.00e-176	610.00
IUUC-Tre-121884	Trichoderma reesei	33.75	1.00e-11	64.70
IUUC-Tvi-122552	Trichoderma virens	33.75	7.00e-12	65.90
IUUC-Tbe-127523	Tupaia belangeri	86.01	0.00e+00	1053.00
IUUC-Ttr-128954	Tursiops truncatus	87.30	0.00e+00	1050.00
IUUC-Vpa-130441	Vicugna pacos	87.74	0.00e+00	1063.00
IUUC-Xtr-132031	Xenopus tropicalis	57.55	0.00e+00	652.00
IUUC-Xma-132984	Xiphophorus maculatus	53.51	2.00e-176	612.00
IUUC-Yli-134629	Yarrowia lipolytica	32.24	4.00e-16	79.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence