iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.30e-09	38.3	12	76
E3 activity/RING/RING	2.00e-09	39.0	16	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrliq 66
           +e +CpI l+  +dPv++++G+ + rs+I+ + a ++   +cPv+r++ ++++l  n  l ++i+
   Q: 12   KETKCPICLDDLTDPVTVECGHNFCRSCIKDFWAGQQAtsSCPVCRHQCQHRNLRSNAQLGNMIE 76
           6889***************************9877666779******************999997 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+d+ d p+++ CgH f+++C+   w      ++ + +CP+Cr
   Q: 16   CPICLDDLTD-PVTVECGHNFCRSCIkDFW----AGQQATSSCPVCR 57
           **********.999************7778....88999999****8 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MAHVEVLARL QKETKCPICL DDLTDPVTVE CGHNFCRSCI KDFWAGQQAT SSCPVCRHQC 60
QHRNLRSNAQ LGNMIETAQL LQGMENKRHE SSTSCERHNQ ALTLFCEDDL QLLCDQCVEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTAATTAC ATAGGTCTGG CATGTAAATG AGTTGGCTCA TTATTCAGGG AGCCCTGAGA 60
TGATGTTCAG CAGAACAAGG ACCAGGGTTG GGCACAGGTG TGCATAATTA ATTGGCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005615--C:extracellular space
GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding

KEGG

mmu:333307

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001835	Ailuropoda melanoleuca	48.09	2.00e-118	419.00
IUUC-Cel-018208	Caenorhabditis elegans	31.75	1.00e-09	58.20
IUUC-Cja-019332	Callithrix jacchus	48.30	5.00e-126	444.00
IUUC-Cme-027215	Cyanidioschyzon merolae	46.15	2.00e-09	57.00
IUUC-Eca-033513	Equus caballus	45.81	1.00e-108	386.00
IUUC-Fca-036248	Felis catus	49.36	1.00e-124	439.00
IUUC-Ggo-044952	Gorilla gorilla	49.36	4.00e-125	441.00
IUUC-Laf-054199	Loxodonta africana	44.49	1.00e-106	379.00
IUUC-Mpu-065865	Mustela putorius furo	48.71	3.00e-115	408.00
IUUC-Mlu-068022	Myotis lucifugus	43.28	3.00e-112	398.00
IUUC-Nle-069929	Nomascus leucogenys	49.36	2.00e-127	449.00
IUUC-Ocu-074204	Oryctolagus cuniculus	47.66	2.00e-128	452.00
IUUC-Oga-088661	Otolemur garnettii	48.03	1.00e-120	426.00
IUUC-Pab-097844	Pongo abelii	48.82	1.00e-123	436.00
IUUC-Ssc-115235	Sus scrofa	38.48	3.00e-84	305.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence