iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090580

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03107955

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000008743.2	ENSPTRT00000016095.2	ENSPTRP00000014892.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.20e-09	38.5	14	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++C+e f        ++l+CgHvf++dCl k+     ++ +   +++  CP+Cr
   Q: 14   CPVCYEKFrdleG-ASRTLSCGHVFCHDCLVKYllstrVDGQ--VQRTLVCPICR 65
           ********55532.3899************999888655555..888889****8 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSEGESKDSS GSECPVCYEK FRDLEGASRT LSCGHVFCHD CLVKYLLSTR VDGQVQRTLV 60
CPICRYVTFL SKKSSRWPSM LDKSSQTLAV PVGLPSVPPL DSLGHTNPLA ASSSAWRPPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGAAG GGGAGAGCAA GGACAGCTCG GGCAGTGAGT GCCCCGTGTG CTATGAGAAG 60
TTCCGGGACC TGGAGGGCGC CAGCCGGACG CTGAGCTGTG GCCATGTGTT CTGCCATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

ptr:468400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	91.40	5.00e-48	182.00
IUUC-Atr-002488	Amborella trichopoda	31.75	2.00e-06	45.80
IUUC-Apl-003509	Anas platyrhynchos	46.88	4.00e-36	144.00
IUUC-Aca-004916	Anolis carolinensis	41.46	7.00e-23	100.00
IUUC-Aly-006067	Arabidopsis lyrata	32.35	2.00e-07	48.90
IUUC-Bta-013443	Bos taurus	79.33	2.00e-67	248.00
IUUC-Cja-019637	Callithrix jacchus	95.65	3.00e-80	290.00
IUUC-Cfa-020737	Canis familiaris	76.11	9.00e-64	236.00
IUUC-Cpo-022224	Cavia porcellus	81.40	1.00e-62	232.00
IUUC-Csa-024175	Chlorocebus sabaeus	95.53	1.00e-89	322.00
IUUC-Dre-028060	Danio rerio	34.25	1.00e-21	95.50
IUUC-Dno-030024	Dasypus novemcinctus	84.43	2.00e-69	254.00
IUUC-Dor-030936	Dipodomys ordii	78.77	1.00e-69	255.00
IUUC-Eca-033759	Equus caballus	84.90	2.00e-78	284.00
IUUC-Fal-037142	Ficedula albicollis	41.55	4.00e-29	120.00
IUUC-Gmo-039196	Gadus morhua	36.71	2.00e-20	92.40
IUUC-Gga-041189	Gallus gallus	46.39	3.00e-34	137.00
IUUC-Gac-041497	Gasterosteus aculeatus	39.39	2.00e-22	98.60
IUUC-Ggo-045020	Gorilla gorilla	98.19	2.00e-91	328.00
IUUC-Hsa-046317	Homo sapiens	99.40	1.00e-72	265.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	82.68	3.00e-75	274.00
IUUC-Lch-049885	Latimeria chalumnae	38.69	9.00e-23	99.80
IUUC-Laf-053457	Loxodonta africana	79.89	3.00e-72	264.00
IUUC-Mcc-054653	Macaca mulatta	96.84	5.00e-80	290.00
IUUC-Mga-059753	Meleagris gallopavo	47.37	1.00e-36	146.00
IUUC-Mmr-061708	Microcebus murinus	37.70	5.00e-07	48.50
IUUC-Mdo-062993	Monodelphis domestica	71.49	1.00e-69	255.00
IUUC-Mmu-063225	Mus musculus	80.45	7.00e-67	246.00
IUUC-Mpu-066299	Mustela putorius furo	80.45	1.00e-65	242.00
IUUC-Mlu-066988	Myotis lucifugus	78.45	8.00e-65	239.00
IUUC-Nle-069011	Nomascus leucogenys	98.10	1.00e-87	315.00
IUUC-Opr-070258	Ochotona princeps	86.59	7.00e-73	266.00
IUUC-Ont-071886	Oreochromis niloticus	40.00	8.00e-24	103.00
IUUC-Ocu-074282	Oryctolagus cuniculus	86.03	2.00e-70	258.00
IUUC-Oga-088403	Otolemur garnettii	81.56	2.00e-74	271.00
IUUC-Oar-089665	Ovis aries	83.67	3.00e-20	89.40
IUUC-Pan-092447	Papio anubis	97.47	1.00e-80	292.00
IUUC-Psi-093673	Pelodiscus sinensis	44.25	3.00e-38	151.00
IUUC-Ppa-095340	Physcomitrella patens	35.14	2.00e-07	49.70
IUUC-Pfo-096933	Poecilia formosa	36.69	3.00e-21	94.70
IUUC-Pab-097867	Pongo abelii	100.00	9.00e-71	259.00
IUUC-Pva-102146	Pteropus vampyrus	83.80	7.00e-73	266.00
IUUC-Rno-105897	Rattus norvegicus	82.68	2.00e-68	251.00
IUUC-Sha-107282	Sarcophilus harrisii	64.59	5.00e-53	200.00
IUUC-Sar-113260	Sorex araneus	82.68	3.00e-76	277.00
IUUC-Ssc-115449	Sus scrofa	79.33	1.00e-52	198.00
IUUC-Tgu-117349	Taeniopygia guttata	39.89	8.00e-28	116.00
IUUC-Xtr-132180	Xenopus tropicalis	53.33	1.00e-23	102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence