iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000003140.1	ENSORLT00000003911.1	ENSORLP00000003910.1
ENSORLG00000003140.1	ENSORLT00000003913.1	ENSORLP00000003912.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-107	360.5	727	1057

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n+p ++e++++  + e++n++n  ++kge+++++  ++++lw +  k +spr+++ +++k++ +f g
   Q: 727  TGLRNLGNTCYMNSILQCLCNTPAMAEYFNSnYYLEDINRSNILGHKGEFAEEFGVIMKALWAGLYKCISPRDFKITIGKINDQFAG 813
           7******************************77889*************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+qqD+qE+l fl+d+l+e+l+k +nk++ +eee+d+   +d+     a++k+k  n+s+i+ lFqgq+ks+++c +c+++s ++e+
   Q: 814  YDQQDSQELLLFLMDGLHEDLNKADNKKRYKEEENDHL--DDQtaadlAWSKHKLLNESIIVALFQGQFKSTVQCSTCHRKSRTFET 898
           *********************99777777777666643..33333556*************************************** PP
   S: 169  fldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvef 255
           f++lslp+ + +++   slqdcL+ f+kee+l+++nk++c++ck++++++kkl+++k+P++L +hLkRfs++ +   ++k+++ v+f
   Q: 899  FMYLSLPLASTSKC---SLQDCLRLFSKEEKLTDNNKVFCRHCKAHRDSTKKLEIWKVPPILLVHLKRFSYEGR--WKQKLQTTVDF 980
           *************9...****************************************************99765..556******** PP
   S: 256  ple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           pl  Ldl+++++ p+++    k+Y L++v +H+G+l++GHY+ay+kn +++ W++fdD++V+e++ ++v++   s aY+lfY 
   Q: 981  PLDnLDLTQYVIGPKQT---LKRYYLYGVSNHYGGLDGGHYTAYCKNATKQrWYKFDDHEVSEISTSSVKS---SAAYILFYS 1057
           *************9988...69*************************88778*******************...********7 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MPAVSTEVKE LYLSTSLGEL NKKAEIKPDK TSTRSYVQSA CKLFKAAEEC RLDRDEEKAY 60
VLYMKYLTVY DIIKKRPDFK QQPEYYITLL GQNSFKKAIE EAEKLSESLK LRYEEAEVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATGGGAAA GACACGAAGA AGAGGAAGCA GGCGGAAGAA GAAATCACAA ATCAGCTGTT 60
AAAAACTAAG TGACTTAGAT GTCAGCAAAG AACTGAAGAA AGGTAAATTG TTTAGTCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF08969--USP8_dimer

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	75.66	0.00e+00	753.00
IUUC-Apl-003226	Anas platyrhynchos	57.17	0.00e+00	1145.00
IUUC-Aca-004936	Anolis carolinensis	57.09	0.00e+00	1031.00
IUUC-Ago-007959	Ashbya gossypii	35.81	9.00e-55	208.00
IUUC-Acl-008102	Aspergillus clavatus	32.52	3.00e-53	203.00
IUUC-Afl-008604	Aspergillus flavus	31.34	8.00e-52	198.00
IUUC-Afu-009001	Aspergillus fumigatus	32.60	6.00e-52	199.00
IUUC-Ani-009291	Aspergillus nidulans	31.59	2.00e-52	201.00
IUUC-Ang-009844	Aspergillus niger	32.88	2.00e-51	197.00
IUUC-Aor-010098	Aspergillus oryzae	31.98	3.00e-51	196.00
IUUC-Ate-010585	Aspergillus terreus	31.51	1.00e-51	198.00
IUUC-Ame-010960	Astyanax mexicanus	83.33	4.00e-89	319.00
IUUC-Bta-013008	Bos taurus	75.60	0.00e+00	756.00
IUUC-Bol-015281	Brassica oleracea	40.30	6.00e-53	201.00
IUUC-Bra-017228	Brassica rapa	40.90	3.00e-53	202.00
IUUC-Cel-018482	Caenorhabditis elegans	32.31	4.00e-52	199.00
IUUC-Cja-019173	Callithrix jacchus	76.22	0.00e+00	756.00
IUUC-Cfa-021243	Canis familiaris	75.66	0.00e+00	754.00
IUUC-Cpo-021522	Cavia porcellus	76.02	0.00e+00	755.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	44.64	4.00e-87	314.00
IUUC-Csa-023616	Chlorocebus sabaeus	76.02	0.00e+00	751.00
IUUC-Cho-024381	Choloepus hoffmanni	66.96	0.00e+00	629.00
IUUC-Cin-025287	Ciona intestinalis	47.65	9.00e-93	335.00
IUUC-Csv-026253	Ciona savignyi	47.29	3.00e-83	303.00
IUUC-Cne-026821	Cryptococcus neoformans	39.89	6.00e-74	273.00
IUUC-Dre-028440	Danio rerio	73.15	0.00e+00	772.00
IUUC-Dno-029039	Dasypus novemcinctus	75.41	0.00e+00	758.00
IUUC-Dor-031043	Dipodomys ordii	80.72	2.00e-114	407.00
IUUC-Dse-031463	Dothistroma septosporum	29.00	4.00e-44	173.00
IUUC-Dme-032089	Drosophila melanogaster	44.08	3.00e-87	316.00
IUUC-Ete-033040	Echinops telfairi	74.68	3.00e-173	602.00
IUUC-Eca-033449	Equus caballus	75.86	0.00e+00	777.00
IUUC-Eeu-034693	Erinaceus europaeus	82.06	4.00e-109	389.00
IUUC-Fca-035794	Felis catus	75.05	0.00e+00	720.00
IUUC-Fal-037322	Ficedula albicollis	74.95	0.00e+00	748.00
IUUC-Gmo-038584	Gadus morhua	76.61	0.00e+00	777.00
IUUC-Gga-041188	Gallus gallus	74.95	0.00e+00	747.00
IUUC-Gac-041850	Gasterosteus aculeatus	75.07	0.00e+00	1451.00
IUUC-Ggo-045565	Gorilla gorilla	76.22	0.00e+00	757.00
IUUC-Hsa-046438	Homo sapiens	76.22	0.00e+00	757.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	76.22	0.00e+00	757.00
IUUC-Kpa-049321	Komagataella pastoris	32.97	7.00e-48	185.00
IUUC-Lch-050485	Latimeria chalumnae	78.46	0.00e+00	778.00
IUUC-Loc-052769	Lepisosteus oculatus	80.08	0.00e+00	797.00
IUUC-Lma-053021	Leptosphaeria maculans	32.26	2.00e-55	210.00
IUUC-Laf-053432	Loxodonta africana	58.14	0.00e+00	1135.00
IUUC-Mcc-055823	Macaca mulatta	76.02	0.00e+00	755.00
IUUC-Meu-056099	Macropus eugenii	83.27	1.00e-141	497.00
IUUC-Mla-059089	Melampsora laricipopulina	41.67	1.00e-72	268.00
IUUC-Mga-059739	Meleagris gallopavo	76.99	0.00e+00	746.00
IUUC-Mvi-060559	Microbotryum violaceum	41.29	1.00e-79	291.00
IUUC-Mmr-061158	Microcebus murinus	76.37	0.00e+00	753.00
IUUC-Mdo-061801	Monodelphis domestica	75.41	0.00e+00	752.00
IUUC-Mmu-063665	Mus musculus	73.61	0.00e+00	754.00
IUUC-Mpu-066738	Mustela putorius furo	75.46	0.00e+00	751.00
IUUC-Mlu-067307	Myotis lucifugus	75.30	0.00e+00	771.00
IUUC-Nfi-068410	Neosartorya fischeri	32.60	4.00e-52	200.00
IUUC-Nle-069314	Nomascus leucogenys	76.02	0.00e+00	755.00
IUUC-Opr-070378	Ochotona princeps	70.26	8.00e-105	375.00
IUUC-Ont-071545	Oreochromis niloticus	88.39	0.00e+00	909.00
IUUC-Oan-073537	Ornithorhynchus anatinus	73.40	0.00e+00	748.00
IUUC-Ocu-074193	Oryctolagus cuniculus	75.81	0.00e+00	755.00
IUUC-Oga-088271	Otolemur garnettii	75.30	0.00e+00	759.00
IUUC-Oar-090431	Ovis aries	75.60	0.00e+00	757.00
IUUC-Ptr-091339	Pan troglodytes	76.02	0.00e+00	756.00
IUUC-Pan-092266	Papio anubis	78.31	2.00e-153	534.00
IUUC-Psi-093187	Pelodiscus sinensis	54.56	6.00e-111	395.00
IUUC-Pma-094626	Petromyzon marinus	54.59	5.00e-139	487.00
IUUC-Pfo-096463	Poecilia formosa	89.11	0.00e+00	878.00
IUUC-Pab-097645	Pongo abelii	76.02	0.00e+00	755.00
IUUC-Pva-103222	Pteropus vampyrus	78.67	5.00e-177	615.00
IUUC-Pgr-103408	Puccinia graminis	38.35	1.00e-55	212.00
IUUC-Ptt-103699	Puccinia triticina	47.20	1.00e-67	251.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	30.03	2.00e-52	201.00
IUUC-Rno-105510	Rattus norvegicus	75.61	0.00e+00	761.00
IUUC-Sce-106435	Saccharomyces cerevisiae	36.84	9.00e-57	215.00
IUUC-Sha-106879	Sarcophilus harrisii	74.95	0.00e+00	748.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	34.28	7.00e-49	188.00
IUUC-Smo-108711	Selaginella moellendorffii	35.00	3.00e-53	202.00
IUUC-Sar-113019	Sorex araneus	74.73	0.00e+00	705.00
IUUC-Sre-115031	Sporisorium reilianum	38.16	2.00e-71	264.00
IUUC-Ssc-116334	Sus scrofa	75.30	0.00e+00	752.00
IUUC-Tgu-117062	Taeniopygia guttata	76.99	0.00e+00	746.00
IUUC-Tru-117908	Takifugu rubripes	91.67	0.00e+00	874.00
IUUC-Tsy-118867	Tarsius syrichta	67.89	0.00e+00	649.00
IUUC-Tni-120206	Tetraodon nigroviridis	73.06	0.00e+00	1408.00
IUUC-Tme-127144	Tuber melanosporum	41.10	2.00e-80	294.00
IUUC-Tbe-127877	Tupaia belangeri	81.25	9.00e-68	252.00
IUUC-Ttr-128580	Tursiops truncatus	76.27	0.00e+00	759.00
IUUC-Uma-129340	Ustilago maydis	39.39	2.00e-73	270.00
IUUC-Vpa-130541	Vicugna pacos	74.04	0.00e+00	730.00
IUUC-Xtr-132161	Xenopus tropicalis	69.64	0.00e+00	731.00
IUUC-Xma-134271	Xiphophorus maculatus	88.91	0.00e+00	880.00
IUUC-Yli-134561	Yarrowia lipolytica	36.69	3.00e-58	220.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence