iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000012852.8	ENSRNOT00000042287.6	ENSRNOP00000042320.5
ENSRNOG00000012852.8	ENSRNOT00000049898.4	ENSRNOP00000040191.4
ENSRNOG00000012852.8	ENSRNOT00000017573.7	ENSRNOP00000017573.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-26	91.3	517	589

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvk........elegkrGlfPenFvekle 63
           +++kvq+++dy+a+++deL+lk+Gdvvlvi   ++eeqdegWl+gvk        ele++rG+fPenF+e+++
   Q: 517  FMFKVQAQHDYTATDTDELQLKAGDVVLVIpfqNPEEQDEGWLMGVKesdwnqhkELEKCRGVFPENFTERVQ 589
           799********************************************************************96 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR 60
LQKDLRTYLA SVKAMHEASK KLSECLQEVY EPEWPGRDEA NKIAENNDLL WMDYHQKLVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCTCCCT CCCTGGATCC CCGCGTTGCT CACTCGCTCT CCCCGCGCAC GCTCCGTCTC 60
CGTCAGTCCC CTGAGCTGTT CTAGTGCGCG GCGTGGAGCC AGGCAGGGCT CAGGCTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR003005--Amphiphysin
IPR003023--Amphiphysin_2
IPR004148--BAR_dom
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF14604--SH3_9

PRINTS

PR01251--AMPHIPHYSIN
PR01253--AMPHIPHYSIN2
PR00452--SH3DOMAIN

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0030424--C:axon
GO:0005829--C:cytosol
GO:0060987--C:lipid tube
GO:0016020--C:membrane
GO:0005635--C:nuclear envelope
GO:0060988--P:lipid tube assembly
GO:0042692--P:muscle cell differentiation
GO:0051647--P:nucleus localization
GO:0006997--P:nucleus organization
GO:0043065--P:positive regulation of apoptotic process
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0071156--P:regulation of cell cycle arrest
GO:0030100--P:regulation of endocytosis
GO:0045664--P:regulation of neuron differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001292	Ailuropoda melanoleuca	85.44	1.00e-171	596.00
IUUC-Apl-003830	Anas platyrhynchos	75.29	0.00e+00	833.00
IUUC-Aca-005149	Anolis carolinensis	64.43	0.00e+00	683.00
IUUC-Ath-007087	Arabidopsis thaliana	44.44	1.20e+00	26.90
IUUC-Ame-011551	Astyanax mexicanus	49.01	1.00e-133	470.00
IUUC-Bta-013069	Bos taurus	92.66	0.00e+00	981.00
IUUC-Cja-019089	Callithrix jacchus	92.42	0.00e+00	1033.00
IUUC-Cfa-020825	Canis familiaris	78.68	2.00e-172	599.00
IUUC-Cpo-022197	Cavia porcellus	94.07	0.00e+00	984.00
IUUC-Csa-023301	Chlorocebus sabaeus	91.46	0.00e+00	1050.00
IUUC-Dre-028384	Danio rerio	67.70	6.00e-110	390.00
IUUC-Dno-029712	Dasypus novemcinctus	93.70	0.00e+00	800.00
IUUC-Dor-030441	Dipodomys ordii	81.74	0.00e+00	631.00
IUUC-Ete-032582	Echinops telfairi	71.43	0.00e+00	677.00
IUUC-Eca-034380	Equus caballus	92.78	0.00e+00	995.00
IUUC-Eeu-035316	Erinaceus europaeus	88.81	2.00e-145	509.00
IUUC-Fca-036228	Felis catus	79.76	2.00e-166	579.00
IUUC-Fal-037539	Ficedula albicollis	74.28	0.00e+00	853.00
IUUC-Gmo-039190	Gadus morhua	49.08	3.00e-139	488.00
IUUC-Gga-041247	Gallus gallus	78.93	3.00e-144	504.00
IUUC-Gac-042188	Gasterosteus aculeatus	51.58	8.00e-155	540.00
IUUC-Ggo-044521	Gorilla gorilla	92.06	0.00e+00	997.00
IUUC-Hsa-046050	Homo sapiens	93.77	0.00e+00	1059.00
IUUC-Itr-048478	Ictidomys tridecemlineatus	97.61	0.00e+00	716.00
IUUC-Lch-050550	Latimeria chalumnae	66.91	4.00e-128	451.00
IUUC-Mcc-055717	Macaca mulatta	88.72	0.00e+00	994.00
IUUC-Meu-056110	Macropus eugenii	76.30	9.00e-116	409.00
IUUC-Mga-059369	Meleagris gallopavo	75.06	6.00e-158	551.00
IUUC-Mmr-061149	Microcebus murinus	92.61	0.00e+00	1030.00
IUUC-Mdo-062533	Monodelphis domestica	77.14	0.00e+00	793.00
IUUC-Mmu-063911	Mus musculus	98.98	0.00e+00	1131.00
IUUC-Mpu-066246	Mustela putorius furo	93.78	0.00e+00	1048.00
IUUC-Nle-069141	Nomascus leucogenys	86.74	0.00e+00	952.00
IUUC-Opr-070200	Ochotona princeps	80.77	4.00e-160	558.00
IUUC-Ont-071795	Oreochromis niloticus	67.88	6.00e-105	374.00
IUUC-Ocu-074817	Oryctolagus cuniculus	80.24	0.00e+00	800.00
IUUC-Oin-079195	Oryza indica	45.16	2.40e-02	30.80
IUUC-Ola-087308	Oryzias latipes	46.48	7.00e-141	494.00
IUUC-Oga-088872	Otolemur garnettii	85.13	1.00e-160	559.00
IUUC-Ptr-091125	Pan troglodytes	92.31	0.00e+00	1024.00
IUUC-Pan-092349	Papio anubis	93.91	0.00e+00	1055.00
IUUC-Psi-093226	Pelodiscus sinensis	76.70	0.00e+00	814.00
IUUC-Pma-094139	Petromyzon marinus	50.83	2.00e-155	542.00
IUUC-Pfo-096470	Poecilia formosa	53.40	4.00e-112	399.00
IUUC-Pab-098085	Pongo abelii	81.14	0.00e+00	850.00
IUUC-Pop-098870	Populus trichocarpa	31.58	6.00e-05	40.40
IUUC-Pca-100306	Procavia capensis	85.16	2.00e-136	479.00
IUUC-Pva-103041	Pteropus vampyrus	83.36	0.00e+00	903.00
IUUC-Sar-113470	Sorex araneus	72.59	2.00e-112	399.00
IUUC-Tgu-117501	Taeniopygia guttata	79.23	2.00e-144	505.00
IUUC-Tru-118163	Takifugu rubripes	48.70	8.00e-146	510.00
IUUC-Tni-120465	Tetraodon nigroviridis	50.92	2.00e-141	496.00
IUUC-Tbe-127789	Tupaia belangeri	84.05	0.00e+00	635.00
IUUC-Ttr-129084	Tursiops truncatus	97.30	9.00e-171	593.00
IUUC-Xtr-132870	Xenopus tropicalis	60.07	3.00e-167	582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence