iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044687

Ensembl Protein ID

ENSGGOP00000019989.1

UniProt Accession

G3RW08; G3RW08_GORGO

Protein Name

Uncharacterized protein

Gene Name

NACC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000000393.2	ENSGGOT00000029601.1	ENSGGOP00000019989.1
ENSGGOG00000000393.2	ENSGGOT00000000395.2	ENSGGOP00000000386.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	6.40e-16	58.9	30	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv +vv+g+ f+ah++vLaasS +F++lf+++     sk+  e+ + v p +f+++l+F+Ytg+l++
   Q: 30   CDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGN-----SKSAFELPGsVPPACFQQILSFCYTGRLTM 92
           8*****************************774.....46778***88*****************987 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS 60
GNSKSAFELP GSVPPACFQQ ILSFCYTGRL TMTASEQLVV MYTAGFLQIQ HIVERGTDLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCAGA TGCTGCACAT CGAGATCCCC AACTTCGGGA ACACAGTGCT GGGCTGCCTG 60
AACGAGCAGC GCCTGCTGGG CCTCTACTGC GATGTGTCCA TCGTGGTCAA GGGCCAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018379--BEN_domain
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS51457--BEN
PS50097--BTB

Pfam

PF10523--BEN
PF00651--BTB

SMART

SM01025--BEN
SM00225--BTB

Gene Ontology

GO:0005739--C:mitochondrion
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0004407--F:histone deacetylase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076--F:transcription factor activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0034629--P:cellular protein complex localization
GO:0008285--P:negative regulation of cell proliferation
GO:1900477--P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001902	Ailuropoda melanoleuca	71.91	0.00e+00	647.00
IUUC-Apl-004203	Anas platyrhynchos	66.50	0.00e+00	724.00
IUUC-Ame-011046	Astyanax mexicanus	59.29	2.00e-76	279.00
IUUC-Bta-012908	Bos taurus	73.23	0.00e+00	749.00
IUUC-Cja-019140	Callithrix jacchus	73.19	0.00e+00	789.00
IUUC-Cfa-020493	Canis familiaris	97.57	7.00e-143	500.00
IUUC-Cpo-022399	Cavia porcellus	70.83	0.00e+00	786.00
IUUC-Csa-024135	Chlorocebus sabaeus	74.49	0.00e+00	803.00
IUUC-Dre-027761	Danio rerio	62.75	3.00e-79	288.00
IUUC-Dno-029271	Dasypus novemcinctus	75.58	8.00e-92	330.00
IUUC-Ete-032427	Echinops telfairi	69.22	0.00e+00	710.00
IUUC-Eca-033986	Equus caballus	72.54	0.00e+00	780.00
IUUC-Eeu-035211	Erinaceus europaeus	70.80	0.00e+00	767.00
IUUC-Fca-035733	Felis catus	71.36	0.00e+00	694.00
IUUC-Fal-037348	Ficedula albicollis	65.14	0.00e+00	712.00
IUUC-Gmo-039529	Gadus morhua	89.22	1.00e-87	317.00
IUUC-Gga-040405	Gallus gallus	67.63	0.00e+00	733.00
IUUC-Hsa-045955	Homo sapiens	77.11	0.00e+00	791.00
IUUC-Itr-048872	Ictidomys tridecemlineatus	73.81	0.00e+00	774.00
IUUC-Lch-049615	Latimeria chalumnae	61.06	0.00e+00	681.00
IUUC-Loc-051881	Lepisosteus oculatus	83.96	1.00e-102	366.00
IUUC-Lma-053325	Leptosphaeria maculans	35.09	5.00e-06	44.70
IUUC-Laf-054170	Loxodonta africana	67.67	0.00e+00	684.00
IUUC-Mga-059627	Meleagris gallopavo	67.80	0.00e+00	730.00
IUUC-Mdo-063014	Monodelphis domestica	84.19	4.00e-138	484.00
IUUC-Mmu-063897	Mus musculus	72.34	0.00e+00	790.00
IUUC-Mpu-066806	Mustela putorius furo	71.74	0.00e+00	731.00
IUUC-Nle-069114	Nomascus leucogenys	72.89	0.00e+00	712.00
IUUC-Opr-071127	Ochotona princeps	94.57	1.00e-70	260.00
IUUC-Ont-071693	Oreochromis niloticus	83.85	2.00e-94	339.00
IUUC-Oan-073510	Ornithorhynchus anatinus	69.35	0.00e+00	752.00
IUUC-Ola-086572	Oryzias latipes	59.07	1.00e-158	553.00
IUUC-Oga-088653	Otolemur garnettii	73.19	0.00e+00	779.00
IUUC-Oar-089811	Ovis aries	69.41	5.00e-176	610.00
IUUC-Ptr-090703	Pan troglodytes	76.88	0.00e+00	786.00
IUUC-Pan-092388	Papio anubis	73.95	0.00e+00	800.00
IUUC-Psi-093786	Pelodiscus sinensis	67.57	0.00e+00	743.00
IUUC-Pma-094566	Petromyzon marinus	73.03	1.00e-63	236.00
IUUC-Pca-101090	Procavia capensis	69.68	0.00e+00	712.00
IUUC-Pva-102843	Pteropus vampyrus	69.68	0.00e+00	756.00
IUUC-Rno-105139	Rattus norvegicus	72.47	0.00e+00	795.00
IUUC-Sha-107545	Sarcophilus harrisii	68.57	0.00e+00	733.00
IUUC-Tgu-117401	Taeniopygia guttata	66.84	0.00e+00	727.00
IUUC-Tru-118080	Takifugu rubripes	84.41	5.00e-91	328.00
IUUC-Tni-120321	Tetraodon nigroviridis	77.21	7.00e-94	337.00
IUUC-Ttr-128369	Tursiops truncatus	68.96	5.00e-147	513.00
IUUC-Xtr-131793	Xenopus tropicalis	57.02	1.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence