iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118681

UUCD1 version

UUC-TaR-00829

Ensembl Protein ID

ENSTRUP00000038856.1

UniProt Accession

H2UPI5; H2UPI5_TAKRU

Protein Name

Uncharacterized protein

Gene Name

ube3b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000015209.1	ENSTRUT00000038995.1	ENSTRUP00000038856.1
ENSTRUG00000015209.1	ENSTRUT00000038996.1	ENSTRUP00000038857.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.30e-113	379.1	705	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+++++++  l+p+p+s++++ +hl+lFef+G++lgka+++g
   Q: 705  SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNE-RLYPSPTSYIHE-NHLQLFEFVGKMLGKAIYEG 789
           67899*****************************************9888655.569*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + d+ +lgl+l++  +e+++g+  ++eL+pgG+++pVtn
   Q: 790  IVVDVPFASFFLSQVLGHhhstfYSSIDELPSLDSEFYKNLTSIKRY-DGDVGDLGLTLSY--DEDVMGQLVCHELIPGGKTMPVTN 873
           ******************777777999********************.7899998777776..5999******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ikeq++af +Gf+++i++e+l +F++ e++ l++G+ +eid++dlkk+t y gg+++++++i+w+w++l
   Q: 874  ENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLVSGDnAEIDLDDLKKHTVYYGGFHSSHRVIIWLWDIL 960
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f++eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+
   Q: 961  sSDFTAEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSK 1047
           999************************************************************9999******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1048 KSILRDKLRYAISMNTGFELS 1068
           ******************985 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MFTVPQSSKT EFLDKARQAR EERKGQKDKE KSATHIQALV RGFLSRIRLK KQIRKEVDDY 60
FFAYEGGTSK KNALSIFKIA RKLLFIYDRG DKMRFEKLCR AILASMEVEN EPKAWYVSLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTACAG TTCCTCAAAG TTCTAAGACG GAGTTCTTGG ATAAAGCCAG ACAAGCCAGA 60
GAGGAAAGAA AAGGACAGAA GGACAAGGAG AAATCAGCAA CGCACATCCA AGCCCTTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

tru:101079251

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.86	2.00e-106	380.00
IUUC-Aml-002107	Ailuropoda melanoleuca	80.47	0.00e+00	1784.00
IUUC-Atr-003017	Amborella trichopoda	39.72	5.00e-114	405.00
IUUC-Apl-003328	Anas platyrhynchos	83.35	0.00e+00	1784.00
IUUC-Aly-005794	Arabidopsis lyrata	39.29	2.00e-108	387.00
IUUC-Ath-007269	Arabidopsis thaliana	39.82	1.00e-111	397.00
IUUC-Bta-013547	Bos taurus	80.28	0.00e+00	1809.00
IUUC-Bdi-014502	Brachypodium distachyon	39.86	3.00e-111	397.00
IUUC-Bol-015093	Brassica oleracea	40.00	3.00e-112	399.00
IUUC-Bra-016722	Brassica rapa	40.18	3.00e-113	403.00
IUUC-Cel-018447	Caenorhabditis elegans	38.06	0.00e+00	680.00
IUUC-Cja-019855	Callithrix jacchus	79.91	0.00e+00	1772.00
IUUC-Cfa-020066	Canis familiaris	80.64	0.00e+00	1764.00
IUUC-Cpo-021504	Cavia porcellus	80.26	0.00e+00	1800.00
IUUC-Csa-023579	Chlorocebus sabaeus	80.19	0.00e+00	1778.00
IUUC-Cho-024430	Choloepus hoffmanni	69.72	0.00e+00	1282.00
IUUC-Cin-025750	Ciona intestinalis	45.13	0.00e+00	946.00
IUUC-Csv-026016	Ciona savignyi	47.49	0.00e+00	1009.00
IUUC-Dre-028271	Danio rerio	90.65	0.00e+00	1933.00
IUUC-Dno-029054	Dasypus novemcinctus	81.12	0.00e+00	1799.00
IUUC-Dor-030938	Dipodomys ordii	74.46	0.00e+00	1608.00
IUUC-Dme-031602	Drosophila melanogaster	47.70	0.00e+00	969.00
IUUC-Ete-033041	Echinops telfairi	64.78	0.00e+00	1168.00
IUUC-Eca-034411	Equus caballus	81.03	0.00e+00	1773.00
IUUC-Eeu-035201	Erinaceus europaeus	76.51	0.00e+00	746.00
IUUC-Fca-036594	Felis catus	79.44	0.00e+00	1748.00
IUUC-Fal-037317	Ficedula albicollis	80.00	0.00e+00	1796.00
IUUC-Gmo-039412	Gadus morhua	88.44	0.00e+00	1937.00
IUUC-Gga-040149	Gallus gallus	83.74	0.00e+00	1821.00
IUUC-Gac-042088	Gasterosteus aculeatus	94.40	0.00e+00	2046.00
IUUC-Gma-043839	Glycine max	40.67	5.00e-113	402.00
IUUC-Ggo-045279	Gorilla gorilla	80.19	0.00e+00	1778.00
IUUC-Hsa-045660	Homo sapiens	80.09	0.00e+00	1774.00
IUUC-Hvu-047770	Hordeum vulgare	36.66	6.00e-109	388.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	72.24	0.00e+00	831.00
IUUC-Lch-050664	Latimeria chalumnae	85.06	0.00e+00	1864.00
IUUC-Lpe-050755	Leersia perrieri	37.37	6.00e-99	355.00
IUUC-Loc-052791	Lepisosteus oculatus	90.40	0.00e+00	1940.00
IUUC-Laf-053902	Loxodonta africana	81.03	0.00e+00	1793.00
IUUC-Mcc-054730	Macaca mulatta	80.09	0.00e+00	1777.00
IUUC-Meu-056527	Macropus eugenii	75.65	0.00e+00	1612.00
IUUC-Mtr-057671	Medicago truncatula	40.32	3.00e-112	399.00
IUUC-Mga-059260	Meleagris gallopavo	83.40	0.00e+00	1817.00
IUUC-Mmr-060804	Microcebus murinus	79.61	0.00e+00	1736.00
IUUC-Mdo-062575	Monodelphis domestica	79.74	0.00e+00	1719.00
IUUC-Mmu-063636	Mus musculus	79.07	0.00e+00	1704.00
IUUC-Mac-064989	Musa acuminata	39.82	7.00e-110	392.00
IUUC-Mpu-066677	Mustela putorius furo	79.64	0.00e+00	1662.00
IUUC-Mlu-067952	Myotis lucifugus	80.82	0.00e+00	1739.00
IUUC-Nle-069153	Nomascus leucogenys	80.19	0.00e+00	1776.00
IUUC-Opr-070554	Ochotona princeps	81.31	0.00e+00	1652.00
IUUC-Ont-071372	Oreochromis niloticus	94.66	0.00e+00	2012.00
IUUC-Oan-073327	Ornithorhynchus anatinus	68.75	0.00e+00	733.00
IUUC-Ocu-074183	Oryctolagus cuniculus	79.16	0.00e+00	1751.00
IUUC-Oba-075006	Oryza barthii	37.40	1.00e-111	397.00
IUUC-Obr-076133	Oryza brachyantha	36.23	1.00e-111	397.00
IUUC-Ogl-077003	Oryza glaberrima	37.40	1.00e-111	398.00
IUUC-Ogu-078947	Oryza glumaepatula	37.44	6.00e-112	398.00
IUUC-Oin-080058	Oryza indica	39.79	2.00e-109	390.00
IUUC-Olo-080475	Oryza longistaminata	37.34	8.00e-112	398.00
IUUC-Ome-081741	Oryza meridionalis	39.39	2.00e-102	367.00
IUUC-Oni-082385	Oryza nivara	37.44	5.00e-112	399.00
IUUC-Opu-083176	Oryza punctata	37.80	8.00e-111	395.00
IUUC-Oru-084554	Oryza rufipogon	35.13	8.00e-99	355.00
IUUC-Osa-085355	Oryza sativa	37.34	8.00e-112	398.00
IUUC-Ola-087337	Oryzias latipes	93.82	0.00e+00	1942.00
IUUC-Oga-088342	Otolemur garnettii	79.83	0.00e+00	1710.00
IUUC-Oar-090234	Ovis aries	79.70	0.00e+00	1781.00
IUUC-Ptr-091661	Pan troglodytes	80.19	0.00e+00	1777.00
IUUC-Pan-092728	Papio anubis	79.93	0.00e+00	1773.00
IUUC-Psi-093251	Pelodiscus sinensis	83.02	0.00e+00	1691.00
IUUC-Pma-094195	Petromyzon marinus	70.46	0.00e+00	1463.00
IUUC-Ppa-095544	Physcomitrella patens	38.03	1.00e-112	401.00
IUUC-Pfo-097472	Poecilia formosa	95.32	0.00e+00	2032.00
IUUC-Pab-098570	Pongo abelii	80.37	0.00e+00	1781.00
IUUC-Pca-100110	Procavia capensis	70.65	0.00e+00	1494.00
IUUC-Ppe-101281	Prunus persica	39.54	9.00e-108	385.00
IUUC-Pva-102887	Pteropus vampyrus	75.82	0.00e+00	1645.00
IUUC-Rno-106028	Rattus norvegicus	77.12	0.00e+00	1627.00
IUUC-Sha-107331	Sarcophilus harrisii	79.85	0.00e+00	1733.00
IUUC-Smo-109488	Selaginella moellendorffii	38.32	2.00e-108	387.00
IUUC-Sit-109811	Setaria italica	35.52	5.00e-110	392.00
IUUC-Sar-113287	Sorex araneus	66.43	6.00e-163	568.00
IUUC-Sbi-114433	Sorghum bicolor	35.81	7.00e-111	395.00
IUUC-Ssc-116103	Sus scrofa	81.03	0.00e+00	1773.00
IUUC-Tgu-117275	Taeniopygia guttata	82.62	0.00e+00	1796.00
IUUC-Tsy-118985	Tarsius syrichta	69.83	0.00e+00	819.00
IUUC-Tni-120850	Tetraodon nigroviridis	99.75	0.00e+00	831.00
IUUC-Tca-121770	Theobroma cacao	39.54	6.00e-112	399.00
IUUC-Tae-125466	Triticum aestivum	36.51	7.00e-109	388.00
IUUC-Tur-126086	Triticum urartu	39.86	8.00e-106	379.00
IUUC-Tbe-127461	Tupaia belangeri	76.26	0.00e+00	1620.00
IUUC-Ttr-129269	Tursiops truncatus	80.47	0.00e+00	1752.00
IUUC-Vpa-130523	Vicugna pacos	71.19	2.00e-111	397.00
IUUC-Vvi-131524	Vitis vinifera	39.68	8.00e-111	395.00
IUUC-Xtr-132146	Xenopus tropicalis	81.62	0.00e+00	1800.00
IUUC-Xma-133526	Xiphophorus maculatus	95.04	0.00e+00	2029.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence