iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072134

Ensembl Protein ID

ENSONIP00000003797.1

UniProt Accession

I3J4K7; I3J4K7_ORENI

Genbank Protein ID

ENSONIP00000003797

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01004396

Gene Name

usp46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000003033.1	ENSONIT00000003798.1	ENSONIP00000003797.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-98	330.2	35	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 35   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 116
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l++ek+++k++ + +++ +    + e ++k ++++++d+Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 117  MQQDAHEFLNYLLNTVADILQEEKKQEKQNGRLKNNGTVVTTEAETENKTEPTWVHDIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 205
           ********************88777777777777777777778888999999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 206  EQNT-----SITHCLRDFSNTETLCSEYKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 287
           ****.....9**********************************************************************55555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts  ++++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 288  TSG-DAVNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 367
           774.45556****************************.888*******************999*****************97 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTVRNIASIC NMGTNASALE KDIGPEQFPI NEHYFGLVNF GNTCYCNSVL QALYFCRPFR 60
ENVLAYKAQQ KKKENLLTCL ADLFHSIATQ KKKVGVIPPK KFISRLRKEN DLFDNYMQQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGTCA GAAACATCGC CTCCATTTGT AATATGGTGA GTAACTCGCT GCTTTTCCGT 60
GTTGATATCG ATCCGCTTGC AGGCACTGTG CTGAACCTGG TTGTGTGTGT GAGAGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002353	Ailuropoda melanoleuca	93.19	0.00e+00	672.00
IUUC-Apl-003380	Anas platyrhynchos	92.41	0.00e+00	674.00
IUUC-Aca-005031	Anolis carolinensis	95.12	0.00e+00	732.00
IUUC-Ath-006663	Arabidopsis thaliana	59.07	3.00e-125	441.00
IUUC-Ago-007871	Ashbya gossypii	37.16	1.00e-48	188.00
IUUC-Ame-010862	Astyanax mexicanus	97.83	0.00e+00	756.00
IUUC-Bta-013023	Bos taurus	93.41	0.00e+00	669.00
IUUC-Bdi-014008	Brachypodium distachyon	59.73	6.00e-125	440.00
IUUC-Cel-018379	Caenorhabditis elegans	61.67	6.00e-143	500.00
IUUC-Cja-018956	Callithrix jacchus	92.43	0.00e+00	667.00
IUUC-Cfa-021064	Canis familiaris	94.12	0.00e+00	658.00
IUUC-Cpo-022443	Cavia porcellus	93.89	0.00e+00	668.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.48	5.00e-99	354.00
IUUC-Csa-023841	Chlorocebus sabaeus	94.85	0.00e+00	692.00
IUUC-Cne-026900	Cryptococcus neoformans	42.18	1.00e-59	224.00
IUUC-Dre-028230	Danio rerio	96.49	0.00e+00	749.00
IUUC-Dno-029209	Dasypus novemcinctus	92.39	0.00e+00	670.00
IUUC-Dme-032038	Drosophila melanogaster	80.88	1.00e-100	360.00
IUUC-Eca-033721	Equus caballus	95.24	0.00e+00	668.00
IUUC-Eeu-034916	Erinaceus europaeus	92.59	4.00e-153	533.00
IUUC-Fca-036299	Felis catus	92.41	0.00e+00	669.00
IUUC-Fso-038299	Fusarium solani	37.80	1.00e-74	274.00
IUUC-Gmo-038611	Gadus morhua	95.80	0.00e+00	713.00
IUUC-Ggr-039806	Gaeumannomyces graminis	43.48	9.00e-76	278.00
IUUC-Gga-041157	Gallus gallus	95.39	0.00e+00	698.00
IUUC-Gac-041764	Gasterosteus aculeatus	95.08	0.00e+00	726.00
IUUC-Ggo-044659	Gorilla gorilla	92.70	0.00e+00	671.00
IUUC-Hsa-046156	Homo sapiens	94.85	0.00e+00	692.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	94.85	0.00e+00	692.00
IUUC-Kpa-049250	Komagataella pastoris	44.37	7.00e-69	254.00
IUUC-Lch-049969	Latimeria chalumnae	95.12	0.00e+00	687.00
IUUC-Loc-052479	Lepisosteus oculatus	92.14	0.00e+00	703.00
IUUC-Laf-054085	Loxodonta africana	94.85	0.00e+00	692.00
IUUC-Mcc-055566	Macaca mulatta	92.93	0.00e+00	671.00
IUUC-Mpo-057424	Magnaporthe poae	42.86	4.00e-76	279.00
IUUC-Mla-059142	Melampsora laricipopulina	54.27	3.00e-95	343.00
IUUC-Mga-059575	Meleagris gallopavo	95.24	0.00e+00	672.00
IUUC-Mvi-060357	Microbotryum violaceum	52.67	1.00e-76	281.00
IUUC-Mdo-062579	Monodelphis domestica	94.85	0.00e+00	692.00
IUUC-Mmu-063611	Mus musculus	94.85	0.00e+00	692.00
IUUC-Mac-065323	Musa acuminata	60.11	3.00e-122	431.00
IUUC-Mpu-066038	Mustela putorius furo	93.84	0.00e+00	667.00
IUUC-Mlu-068183	Myotis lucifugus	92.92	0.00e+00	674.00
IUUC-Nle-069330	Nomascus leucogenys	94.85	0.00e+00	692.00
IUUC-Opr-070980	Ochotona princeps	94.40	0.00e+00	665.00
IUUC-Oan-073583	Ornithorhynchus anatinus	91.06	0.00e+00	671.00
IUUC-Ocu-074923	Oryctolagus cuniculus	93.84	0.00e+00	668.00
IUUC-Ola-086546	Oryzias latipes	96.97	0.00e+00	738.00
IUUC-Olu-087809	Ostreococcus lucimarinus	47.75	2.00e-80	292.00
IUUC-Oga-088073	Otolemur garnettii	95.24	0.00e+00	668.00
IUUC-Oar-089248	Ovis aries	94.68	0.00e+00	666.00
IUUC-Ptr-090814	Pan troglodytes	94.85	0.00e+00	692.00
IUUC-Pan-091753	Papio anubis	94.85	0.00e+00	692.00
IUUC-Psi-094012	Pelodiscus sinensis	95.24	0.00e+00	671.00
IUUC-Pma-094388	Petromyzon marinus	90.08	0.00e+00	700.00
IUUC-Pno-095044	Phaeosphaeria nodorum	45.32	2.00e-79	290.00
IUUC-Ppa-095696	Physcomitrella patens	59.62	3.00e-129	455.00
IUUC-Pfo-097369	Poecilia formosa	99.19	0.00e+00	768.00
IUUC-Pab-098594	Pongo abelii	94.69	0.00e+00	670.00
IUUC-Pca-100913	Procavia capensis	78.49	2.00e-150	525.00
IUUC-Pva-102892	Pteropus vampyrus	94.68	0.00e+00	667.00
IUUC-Rno-104909	Rattus norvegicus	94.58	0.00e+00	691.00
IUUC-Sha-107400	Sarcophilus harrisii	94.68	0.00e+00	666.00
IUUC-Sly-111210	Solanum lycopersicum	59.73	8.00e-126	443.00
IUUC-Ssc-115550	Sus scrofa	94.68	0.00e+00	667.00
IUUC-Tgu-116800	Taeniopygia guttata	95.39	0.00e+00	698.00
IUUC-Tru-118212	Takifugu rubripes	98.64	0.00e+00	763.00
IUUC-Tni-120071	Tetraodon nigroviridis	98.64	0.00e+00	764.00
IUUC-Tme-126890	Tuber melanosporum	46.49	4.00e-91	328.00
IUUC-Vpa-130590	Vicugna pacos	89.94	1.00e-179	622.00
IUUC-Xma-133111	Xiphophorus maculatus	98.92	0.00e+00	766.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence