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Tag Content
UUCD2 ID IUUC-Ssc-115299
UUCD1 version UUC-SuS-00863
Ensembl Protein ID ENSSSCP00000020913.1
UniProt Accession I3LA47; I3LA47_PIG
Genbank Protein ID ENSSSCP00000020913
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID FP340372
Gene Name USP44
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000021307.1 ENSSSCT00000025589.1 ENSSSCP00000020913.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.70e-97 325.8 270 674
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle............kkkeklneenp................................... 42
           tGl+NlgNtCYmNSvLQ+Ls++  +r+++l+                      +                                   
   Q: 270  TGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKldlnrwlsvtanD---------Ktrssykhlpvtdtvyqmndcqeketgslhsrypsl 349
           7******************************8876655443220.........134556677888889999999999999999999999 PP
   S: 43   ......................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk 109
                                 +++  +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el  
   Q: 350  slglsggasksrkmeliqprepSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHEL-- 436
           999999998888888888877777777************************************************************.. PP
   S: 110  eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......slqdcL 191
                  e+++++  +l   +++k  k+  ++++++F+gql sq++cl+cdn+s++ epf+dlsl++p++ +++ +        ++++L
   Q: 437  -------ETTGTRLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKdiasqpcLVTEML 518
           .......7788888999999************************************************9998877788888889***** PP
   S: 192  esftkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspe 269
           ++ft++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c++++
   Q: 519  AKFTETEALEGKI-YVCDQCNSKRRrfsskpvvlteAQKQLMICHLPQVLRLHLKRFRWSGH-NNREKIGVHVGFEEILNMEPYCCRES 605
           **********965.*******999999999999999***********************998.7778********************99 PP
   S: 270  ekqke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
            k+ +  + +Y+L avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++++ev++   ++aY+lfY++
   Q: 606  LKSLRpeCFIYDLAAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLSMCTMDEVCK---AQAYILFYTQ 674
           88876779***************************9999********************...********98 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
MLTMDKCKHI GRLQLAHDHS ILNPQKWHCV DCNTTESIWA CLSCPHVACG RYIEEHALKH 60
FQESSHPVAL EVNEMYVFCY FCDDYVLNDN ATGDLKLLRS TLSAIKSQSY HCTTRSGRVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115299|DUB,USP|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAATTAACAC CGTTCTGCTT AGTTTTCAGA TGCTTCAAGT GTGAACAGAG ACTTTCTTGG 60
ATTATGTGTT TCTCAGCCAG ACTAAGTACA TGCTAACGAT GGATAAGTGC AAACACATCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115299|DUB,USP|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:1904667--P:negative regulation of ubiquitin protein ligase activity
GO:0016579--P:protein deubiquitination
GO:0090231--P:regulation of spindle checkpoint
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG ssc:100516911
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 93.39 0.00e+00 1345.00
IUUC-Apl-003673 Anas platyrhynchos 74.89 0.00e+00 1055.00
IUUC-Aca-004434 Anolis carolinensis 72.59 0.00e+00 1040.00
IUUC-Ame-010986 Astyanax mexicanus 63.73 0.00e+00 876.00
IUUC-Bta-012774 Bos taurus 90.44 0.00e+00 1293.00
IUUC-Cja-019619 Callithrix jacchus 89.90 0.00e+00 1280.00
IUUC-Cfa-020957 Canis familiaris 92.69 0.00e+00 1350.00
IUUC-Csa-023177 Chlorocebus sabaeus 89.20 0.00e+00 1274.00
IUUC-Cho-024877 Choloepus hoffmanni 89.08 0.00e+00 842.00
IUUC-Csv-025814 Ciona savignyi 45.03 2.00e-155 542.00
IUUC-Dre-027878 Danio rerio 63.37 0.00e+00 842.00
IUUC-Dno-029832 Dasypus novemcinctus 91.55 0.00e+00 1333.00
IUUC-Ete-032627 Echinops telfairi 87.80 0.00e+00 1262.00
IUUC-Eca-033863 Equus caballus 87.17 0.00e+00 1248.00
IUUC-Eeu-035225 Erinaceus europaeus 85.79 0.00e+00 1219.00
IUUC-Fca-036288 Felis catus 93.11 0.00e+00 1345.00
IUUC-Fal-037207 Ficedula albicollis 74.75 0.00e+00 1030.00
IUUC-Gga-040457 Gallus gallus 74.93 0.00e+00 1027.00
IUUC-Ggo-044926 Gorilla gorilla 90.04 0.00e+00 1276.00
IUUC-Hsa-046079 Homo sapiens 89.34 0.00e+00 1270.00
IUUC-Itr-048737 Ictidomys tridecemlineatus 91.15 0.00e+00 1292.00
IUUC-Lch-050260 Latimeria chalumnae 67.46 0.00e+00 929.00
IUUC-Loc-051981 Lepisosteus oculatus 76.74 0.00e+00 672.00
IUUC-Laf-054491 Loxodonta africana 88.65 0.00e+00 1220.00
IUUC-Mcc-055694 Macaca mulatta 89.90 0.00e+00 1280.00
IUUC-Mga-059523 Meleagris gallopavo 74.89 0.00e+00 1048.00
IUUC-Mmr-060885 Microcebus murinus 93.13 0.00e+00 1327.00
IUUC-Mdo-063018 Monodelphis domestica 79.46 0.00e+00 1117.00
IUUC-Mmu-064012 Mus musculus 78.23 0.00e+00 1080.00
IUUC-Mpu-066207 Mustela putorius furo 92.12 0.00e+00 1355.00
IUUC-Mlu-066929 Myotis lucifugus 89.01 0.00e+00 1211.00
IUUC-Nle-069313 Nomascus leucogenys 80.03 0.00e+00 1100.00
IUUC-Opr-070375 Ochotona princeps 80.25 0.00e+00 1102.00
IUUC-Ont-071637 Oreochromis niloticus 62.75 0.00e+00 855.00
IUUC-Oan-073030 Ornithorhynchus anatinus 77.55 0.00e+00 850.00
IUUC-Ocu-074836 Oryctolagus cuniculus 86.76 0.00e+00 1228.00
IUUC-Olu-087697 Ostreococcus lucimarinus 33.64 3.00e-41 162.00
IUUC-Oga-088367 Otolemur garnettii 91.87 0.00e+00 1288.00
IUUC-Oar-089953 Ovis aries 92.84 0.00e+00 1348.00
IUUC-Ptr-090980 Pan troglodytes 89.48 0.00e+00 1273.00
IUUC-Pan-092748 Papio anubis 90.03 0.00e+00 1285.00
IUUC-Psi-094078 Pelodiscus sinensis 76.26 0.00e+00 847.00
IUUC-Pab-098514 Pongo abelii 89.90 0.00e+00 1280.00
IUUC-Pva-102984 Pteropus vampyrus 91.84 0.00e+00 1291.00
IUUC-Rno-106019 Rattus norvegicus 79.30 0.00e+00 1138.00
IUUC-Sha-106965 Sarcophilus harrisii 78.14 0.00e+00 1114.00
IUUC-Tgu-117160 Taeniopygia guttata 74.78 0.00e+00 1028.00
IUUC-Tru-118156 Takifugu rubripes 60.68 0.00e+00 832.00
IUUC-Tni-119733 Tetraodon nigroviridis 61.58 0.00e+00 834.00
IUUC-Tbe-128084 Tupaia belangeri 84.83 0.00e+00 1219.00
IUUC-Ttr-128928 Tursiops truncatus 94.80 0.00e+00 1370.00
IUUC-Vpa-130706 Vicugna pacos 93.24 0.00e+00 1346.00
IUUC-Xtr-132061 Xenopus tropicalis 71.71 0.00e+00 938.00
Created Date 25-Jun-2017

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