iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055783

Ensembl Protein ID

ENSMMUP00000007173.3

UniProt Accession

G7N443; F7GRI7; G7N443_MACMU

Genbank Protein ID

AFE76507.1; AFH30397.1; AFI34148.1; AFI34149.1; EHH20297.1

Protein Name

Protein kinase C and casein kinase substrate in neurons protein 2 isoform A

Genbank Nucleotide ID

JSUE03005675; JU473593; JV044077; JV044078; CM001262

Gene Name

PACSIN2; EGK_03119

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005427.3	ENSMMUT00000007636.3	ENSMMUP00000007173.3
ENSMMUG00000005427.3	ENSMMUT00000043947.2	ENSMMUP00000036944.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-16	59.4	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ + ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKM-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 486
           799***********************9.9**********.59*************9885 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV KASLMNDDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTAAGCG GGTCCACGTG GAATGACGCT TATGGCGCAA GTCGGAGGAG CTCCTAATGA 60
CATTAGCTTC TCTGAGTCCC TTGGGAGAGG AAACTTTATG ATAGACTGTA GGATTACGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0016301--F:kinase activity
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	93.62	0.00e+00	861.00
IUUC-Apl-003574	Anas platyrhynchos	86.86	0.00e+00	774.00
IUUC-Aca-004251	Anolis carolinensis	80.62	0.00e+00	740.00
IUUC-Ame-011756	Astyanax mexicanus	66.27	0.00e+00	664.00
IUUC-Bta-013193	Bos taurus	90.33	0.00e+00	804.00
IUUC-Cel-018168	Caenorhabditis elegans	31.52	2.00e-60	226.00
IUUC-Cja-018756	Callithrix jacchus	96.91	0.00e+00	864.00
IUUC-Cfa-020545	Canis familiaris	93.83	0.00e+00	891.00
IUUC-Cpo-022000	Cavia porcellus	89.51	0.00e+00	896.00
IUUC-Csa-024030	Chlorocebus sabaeus	99.55	0.00e+00	801.00
IUUC-Cin-025707	Ciona intestinalis	42.74	2.00e-105	375.00
IUUC-Dre-028104	Danio rerio	63.20	8.00e-162	563.00
IUUC-Dno-029429	Dasypus novemcinctus	92.51	0.00e+00	786.00
IUUC-Dor-030122	Dipodomys ordii	87.04	0.00e+00	784.00
IUUC-Dme-032120	Drosophila melanogaster	42.28	6.00e-104	370.00
IUUC-Eca-033367	Equus caballus	91.77	0.00e+00	840.00
IUUC-Eeu-034821	Erinaceus europaeus	77.37	0.00e+00	675.00
IUUC-Fca-036079	Felis catus	93.80	0.00e+00	857.00
IUUC-Fal-036682	Ficedula albicollis	87.02	0.00e+00	771.00
IUUC-Gmo-039681	Gadus morhua	64.29	2.00e-155	541.00
IUUC-Gga-040717	Gallus gallus	87.23	0.00e+00	774.00
IUUC-Gac-042262	Gasterosteus aculeatus	63.52	3.00e-169	587.00
IUUC-Ggo-044841	Gorilla gorilla	98.77	0.00e+00	853.00
IUUC-Hsa-046411	Homo sapiens	98.97	0.00e+00	854.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	94.24	0.00e+00	835.00
IUUC-Loc-051975	Lepisosteus oculatus	70.02	0.00e+00	682.00
IUUC-Laf-053839	Loxodonta africana	89.56	0.00e+00	815.00
IUUC-Mga-060087	Meleagris gallopavo	81.70	0.00e+00	708.00
IUUC-Mmr-060827	Microcebus murinus	94.86	0.00e+00	872.00
IUUC-Mmu-064109	Mus musculus	94.03	0.00e+00	864.00
IUUC-Mpu-066591	Mustela putorius furo	94.03	0.00e+00	867.00
IUUC-Mlu-067826	Myotis lucifugus	93.42	0.00e+00	861.00
IUUC-Nle-069797	Nomascus leucogenys	99.59	0.00e+00	860.00
IUUC-Oan-073076	Ornithorhynchus anatinus	84.06	9.00e-154	536.00
IUUC-Ocu-074425	Oryctolagus cuniculus	93.21	0.00e+00	836.00
IUUC-Ola-087556	Oryzias latipes	64.45	6.00e-161	560.00
IUUC-Oga-089009	Otolemur garnettii	85.66	0.00e+00	786.00
IUUC-Oar-089806	Ovis aries	90.74	0.00e+00	807.00
IUUC-Ptr-091111	Pan troglodytes	98.56	0.00e+00	850.00
IUUC-Pan-091749	Papio anubis	97.30	0.00e+00	847.00
IUUC-Psi-093704	Pelodiscus sinensis	86.60	0.00e+00	785.00
IUUC-Pfo-096680	Poecilia formosa	62.77	3.00e-166	578.00
IUUC-Pab-098584	Pongo abelii	98.74	3.00e-168	584.00
IUUC-Pva-102649	Pteropus vampyrus	92.80	0.00e+00	835.00
IUUC-Rno-105431	Rattus norvegicus	93.44	0.00e+00	877.00
IUUC-Sha-106641	Sarcophilus harrisii	89.48	0.00e+00	807.00
IUUC-Sar-113461	Sorex araneus	81.89	0.00e+00	726.00
IUUC-Ssc-115349	Sus scrofa	93.40	0.00e+00	830.00
IUUC-Tgu-116876	Taeniopygia guttata	87.23	0.00e+00	772.00
IUUC-Tru-118306	Takifugu rubripes	66.80	5.00e-174	603.00
IUUC-Tsy-118901	Tarsius syrichta	83.58	8.00e-151	526.00
IUUC-Tni-120120	Tetraodon nigroviridis	67.41	2.00e-177	615.00
IUUC-Xtr-132925	Xenopus tropicalis	80.08	0.00e+00	739.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence