iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004188

Ensembl Protein ID

ENSAPLP00000010514.1

UniProt Accession

R0JB93; R0JB93_ANAPL

Genbank Protein ID

EOA94246.1

Protein Name

Zinc/RING finger protein 3

Genbank Nucleotide ID

ADON01136409

Gene Name

ZNRF3; Anapl_12040

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000010783.1	ENSAPLT00000011229.1	ENSAPLP00000010514.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.20e-06	25.8	196	237

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 196  CAICLEKYidGEELRVIPCTHRFHKKCVDPW------LLQHHTCPHCR 237
           ********66334******************......9999******8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LFQMHPLGLC NSNDEEDLYE YGWVGVVKLE QPELEPKPCL TVLGKAKRAV QRGATAVIFD 60
VSENPDAIDQ LNQGLEDPLK RPVVYVKGAD AVKLMNIVNK QKVARARIQH RPPRQPTEYF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTTCAGA TGCATCCACT TGGACTGTGT AATAGCAACG ATGAGGAAGA TTTGTATGAA 60
TACGGCTGGG TAGGAGTGGT GAAGCTGGAA CAGCCAGAGC TAGAACCTAA GCCATGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	72.73	0.00e+00	998.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	4.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.17	3.00e-15	73.90
IUUC-Ame-011764	Astyanax mexicanus	65.15	0.00e+00	775.00
IUUC-Bta-012478	Bos taurus	59.79	5.00e-131	461.00
IUUC-Bol-015945	Brassica oleracea	44.00	9.00e-15	74.30
IUUC-Bra-017899	Brassica rapa	44.00	9.00e-15	73.90
IUUC-Cja-019504	Callithrix jacchus	73.17	0.00e+00	1058.00
IUUC-Cfa-020048	Canis familiaris	71.86	0.00e+00	1014.00
IUUC-Cpo-021725	Cavia porcellus	68.45	0.00e+00	956.00
IUUC-Csa-023586	Chlorocebus sabaeus	72.29	0.00e+00	999.00
IUUC-Cho-024867	Choloepus hoffmanni	83.42	9.00e-177	613.00
IUUC-Cin-025569	Ciona intestinalis	48.97	2.00e-58	219.00
IUUC-Csv-025869	Ciona savignyi	46.50	4.00e-52	199.00
IUUC-Dre-027553	Danio rerio	61.92	0.00e+00	847.00
IUUC-Dno-029370	Dasypus novemcinctus	72.03	0.00e+00	981.00
IUUC-Dor-030816	Dipodomys ordii	67.97	0.00e+00	926.00
IUUC-Ete-033060	Echinops telfairi	66.25	0.00e+00	732.00
IUUC-Eca-034044	Equus caballus	72.77	0.00e+00	1036.00
IUUC-Eeu-034591	Erinaceus europaeus	53.61	2.00e-102	366.00
IUUC-Fca-036000	Felis catus	73.20	0.00e+00	1032.00
IUUC-Fal-037147	Ficedula albicollis	92.83	0.00e+00	1451.00
IUUC-Gmo-039099	Gadus morhua	64.85	4.00e-122	431.00
IUUC-Gga-041243	Gallus gallus	95.59	0.00e+00	1268.00
IUUC-Gac-041340	Gasterosteus aculeatus	53.39	1.00e-129	456.00
IUUC-Gma-044387	Glycine max	53.06	2.00e-14	72.00
IUUC-Ggo-044953	Gorilla gorilla	72.73	0.00e+00	1028.00
IUUC-Hsa-046484	Homo sapiens	72.64	0.00e+00	1036.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	71.36	0.00e+00	1023.00
IUUC-Lch-050004	Latimeria chalumnae	62.85	0.00e+00	759.00
IUUC-Loc-051830	Lepisosteus oculatus	66.39	0.00e+00	860.00
IUUC-Laf-053975	Loxodonta africana	74.05	0.00e+00	992.00
IUUC-Mcc-055302	Macaca mulatta	71.81	0.00e+00	979.00
IUUC-Meu-056263	Macropus eugenii	75.04	0.00e+00	786.00
IUUC-Mtr-058744	Medicago truncatula	40.66	1.00e-13	68.90
IUUC-Mga-059706	Meleagris gallopavo	95.31	0.00e+00	1518.00
IUUC-Mmr-061372	Microcebus murinus	70.33	0.00e+00	959.00
IUUC-Mdo-062651	Monodelphis domestica	63.70	0.00e+00	868.00
IUUC-Mmu-064339	Mus musculus	70.98	0.00e+00	978.00
IUUC-Mac-064852	Musa acuminata	54.55	2.00e-13	70.10
IUUC-Mpu-066211	Mustela putorius furo	71.92	0.00e+00	984.00
IUUC-Mlu-067058	Myotis lucifugus	73.57	0.00e+00	946.00
IUUC-Nle-069886	Nomascus leucogenys	72.30	0.00e+00	1018.00
IUUC-Opr-070218	Ochotona princeps	69.28	0.00e+00	879.00
IUUC-Ont-072483	Oreochromis niloticus	62.45	0.00e+00	827.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.77	0.00e+00	910.00
IUUC-Ocu-073847	Oryctolagus cuniculus	66.55	0.00e+00	846.00
IUUC-Opu-083306	Oryza punctata	65.12	1.00e-12	66.20
IUUC-Ola-087358	Oryzias latipes	66.32	0.00e+00	824.00
IUUC-Oga-088362	Otolemur garnettii	72.34	0.00e+00	1036.00
IUUC-Oar-090197	Ovis aries	89.35	2.00e-93	335.00
IUUC-Ptr-091350	Pan troglodytes	72.40	0.00e+00	1035.00
IUUC-Pan-091700	Papio anubis	71.43	0.00e+00	974.00
IUUC-Psi-093301	Pelodiscus sinensis	81.58	0.00e+00	1253.00
IUUC-Pfo-096917	Poecilia formosa	66.80	0.00e+00	820.00
IUUC-Pab-097932	Pongo abelii	72.46	0.00e+00	1057.00
IUUC-Pop-099640	Populus trichocarpa	57.14	1.00e-14	72.80
IUUC-Pca-101054	Procavia capensis	82.28	0.00e+00	837.00
IUUC-Ppe-101991	Prunus persica	32.43	1.00e-13	68.90
IUUC-Pva-102879	Pteropus vampyrus	72.77	0.00e+00	1024.00
IUUC-Sha-106507	Sarcophilus harrisii	53.69	5.00e-172	597.00
IUUC-Sit-110656	Setaria italica	65.12	9.00e-13	66.20
IUUC-Stu-112198	Solanum tuberosum	41.03	5.00e-12	63.90
IUUC-Sar-113182	Sorex araneus	80.87	2.00e-106	379.00
IUUC-Sbi-114132	Sorghum bicolor	50.00	2.00e-11	62.00
IUUC-Ssc-115966	Sus scrofa	67.74	0.00e+00	856.00
IUUC-Tgu-116864	Taeniopygia guttata	91.19	0.00e+00	1093.00
IUUC-Tru-118502	Takifugu rubripes	64.13	0.00e+00	799.00
IUUC-Tsy-119210	Tarsius syrichta	74.77	0.00e+00	980.00
IUUC-Tni-120344	Tetraodon nigroviridis	56.39	1.00e-143	503.00
IUUC-Tca-121477	Theobroma cacao	33.33	1.00e-13	69.70
IUUC-Tbe-127735	Tupaia belangeri	70.37	6.00e-106	378.00
IUUC-Ttr-128714	Tursiops truncatus	61.58	0.00e+00	804.00
IUUC-Vvi-131731	Vitis vinifera	48.98	4.00e-13	67.40
IUUC-Xtr-132280	Xenopus tropicalis	59.84	0.00e+00	718.00
IUUC-Xma-134192	Xiphophorus maculatus	66.54	0.00e+00	823.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence