iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118488

Ensembl Protein ID

ENSTRUP00000012214.1

UniProt Accession

H2SII2; H2SII2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

arhgef6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005093.1	ENSTRUT00000012274.1	ENSTRUP00000012214.1
ENSTRUG00000005093.1	ENSTRUT00000012275.1	ENSTRUP00000012215.1
ENSTRUG00000005093.1	ENSTRUT00000012276.1	ENSTRUP00000012216.1
ENSTRUG00000005093.1	ENSTRUT00000012277.1	ENSTRUP00000012217.1
ENSTRUG00000005093.1	ENSTRUT00000012278.1	ENSTRUP00000012218.1
ENSTRUG00000005093.1	ENSTRUT00000012279.1	ENSTRUP00000012219.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-15	57.8	119	173

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGdv+ v    ++d+gW++g  +l+gk G fP+n+v++++
   Q: 119  TVKARFNFKQNNEDELSFSKGDVIVVT--RQEDGGWWEG--TLNGKTGWFPSNYVREIK 173
           68999*******************996..999*******..8**************996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

CCQYCQEPRT ESDCISNIRE FLRGCSSLKV EGFEPDWLYT GENFGKVLTT LLAVNFATQG 60
KTFARFGMSV QLGSGSVLSF CLLKSAASHS LSTIKSKSSL RRQSKSVEMA ENGGGGQLTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AGGAGCAGAC CGTAACCTGG TTGATATCGT TGGGCGTCCT CTGCTCGCCT 60
AAGAAGAACA TAGCGGACCC GGAGGAGTTT CTGAAAACTT CGCTGAAGGA TGGGGTCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	54.59	0.00e+00	769.00
IUUC-Apl-003960	Anas platyrhynchos	59.46	0.00e+00	814.00
IUUC-Ame-011546	Astyanax mexicanus	70.17	0.00e+00	1030.00
IUUC-Bta-013527	Bos taurus	56.53	0.00e+00	790.00
IUUC-Bol-016606	Brassica oleracea	25.97	1.20e-01	32.30
IUUC-Cja-018935	Callithrix jacchus	56.27	0.00e+00	773.00
IUUC-Cfa-021269	Canis familiaris	56.32	0.00e+00	771.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	45.31	6.00e-12	67.00
IUUC-Dre-028580	Danio rerio	69.04	0.00e+00	1053.00
IUUC-Dor-030868	Dipodomys ordii	45.88	1.00e-161	563.00
IUUC-Dse-031165	Dothistroma septosporum	44.07	3.00e-12	67.80
IUUC-Eca-033500	Equus caballus	56.47	0.00e+00	765.00
IUUC-Eeu-035269	Erinaceus europaeus	50.33	1.00e-77	284.00
IUUC-Fca-035683	Felis catus	56.47	0.00e+00	770.00
IUUC-Fal-037611	Ficedula albicollis	59.14	0.00e+00	810.00
IUUC-Gmo-038980	Gadus morhua	71.47	0.00e+00	1071.00
IUUC-Gga-040940	Gallus gallus	59.14	0.00e+00	810.00
IUUC-Gac-042203	Gasterosteus aculeatus	73.44	0.00e+00	1134.00
IUUC-Ggo-044755	Gorilla gorilla	56.27	0.00e+00	773.00
IUUC-Hsa-046210	Homo sapiens	56.14	0.00e+00	771.00
IUUC-Hvu-047839	Hordeum vulgare	44.83	1.00e-08	52.00
IUUC-Lch-049517	Latimeria chalumnae	60.37	0.00e+00	843.00
IUUC-Loc-052393	Lepisosteus oculatus	69.03	0.00e+00	1023.00
IUUC-Lma-053273	Leptosphaeria maculans	47.17	1.00e-11	65.90
IUUC-Laf-054196	Loxodonta africana	56.79	0.00e+00	766.00
IUUC-Mcc-055716	Macaca mulatta	56.27	0.00e+00	773.00
IUUC-Meu-056285	Macropus eugenii	56.25	3.00e-126	445.00
IUUC-Mor-056932	Magnaporthe oryzae	42.65	2.00e-12	68.20
IUUC-Mga-060029	Meleagris gallopavo	59.79	0.00e+00	826.00
IUUC-Mmr-060803	Microcebus murinus	56.40	0.00e+00	769.00
IUUC-Mmu-063479	Mus musculus	56.34	0.00e+00	763.00
IUUC-Mpu-066065	Mustela putorius furo	56.34	0.00e+00	756.00
IUUC-Nle-069379	Nomascus leucogenys	56.14	0.00e+00	771.00
IUUC-Ont-072240	Oreochromis niloticus	76.18	0.00e+00	1213.00
IUUC-Oan-073067	Ornithorhynchus anatinus	59.01	0.00e+00	832.00
IUUC-Ocu-074852	Oryctolagus cuniculus	55.96	0.00e+00	765.00
IUUC-Ola-086766	Oryzias latipes	70.44	0.00e+00	1108.00
IUUC-Oga-089048	Otolemur garnettii	55.17	0.00e+00	783.00
IUUC-Oar-089339	Ovis aries	56.47	0.00e+00	785.00
IUUC-Pan-092666	Papio anubis	54.95	0.00e+00	738.00
IUUC-Psi-093116	Pelodiscus sinensis	58.50	0.00e+00	828.00
IUUC-Pfo-097394	Poecilia formosa	75.20	0.00e+00	1156.00
IUUC-Pca-100997	Procavia capensis	52.85	4.00e-175	608.00
IUUC-Pva-102500	Pteropus vampyrus	54.90	0.00e+00	734.00
IUUC-Ptt-103726	Puccinia triticina	33.33	1.00e-10	59.70
IUUC-Rno-104974	Rattus norvegicus	55.61	0.00e+00	755.00
IUUC-Sar-113420	Sorex araneus	54.86	0.00e+00	723.00
IUUC-Tgu-117069	Taeniopygia guttata	58.82	0.00e+00	815.00
IUUC-Tsy-119243	Tarsius syrichta	52.12	4.00e-163	568.00
IUUC-Tni-120584	Tetraodon nigroviridis	79.58	0.00e+00	1174.00
IUUC-Tre-121917	Trichoderma reesei	45.31	2.00e-12	68.20
IUUC-Tvi-122534	Trichoderma virens	45.31	2.00e-12	68.20
IUUC-Tbe-127994	Tupaia belangeri	44.01	5.00e-157	548.00
IUUC-Ttr-128839	Tursiops truncatus	55.22	0.00e+00	738.00
IUUC-Xtr-132624	Xenopus tropicalis	58.02	0.00e+00	831.00
IUUC-Xma-134240	Xiphophorus maculatus	75.72	0.00e+00	1138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence