iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049904

Ensembl Protein ID

ENSLACP00000001074.1

UniProt Accession

H2ZUK3; H2ZUK3_LATCH

Genbank Protein ID

ENSLACP00000001074

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01246087

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000000962.1	ENSLACT00000001084.1	ENSLACP00000001074.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.20e-07	31.5	1081	1184
E3 activity/N-recognin/N-domain	3.40e-33	113.8	200	276
E3 activity/N-recognin/UBR-box	1.90e-29	102.2	71	139

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kd........................................gplvlpCgHvfhadClqkw.............. 29
           C++C+e+     ++                                        g+++++CgHv+ha C+qk+              
   Q: 1081 CILCQEEQevkaDKtamvltaciqrsttltqqkgkvfpnpenfdplfmnsdlawGTHTGSCGHVMHAACWQKYfeavqnmtrhrlha 1167
           8888666654441133444444444444444455555555555555555555557999***************99999999999999 PP
   S: 30   pglknssskefrCPlCr 46
            +  +++++e +CPlC+
   Q: 1168 ELIFDLENGEYLCPLCK 1184
           888899999999****6 PP

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy+qviy+lq+Al ++q+ea+ ++t idkeGRravk+G+ ++c+eak++i ++se+++  pL+ ev
   Q: 200  YYCVLFNDEHHSYDQVIYTLQRALACDQREAQVHTTSIDKEGRRAVKMGTVQICQEAKEVICRQSENISLQPLHAEV 276
           9*************************************************************************986 PP

E3 activity/N-recognin/UBR-box

   S: 2    lCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkl 70
           lCg+vfk get+y+Cr+C++d+t+vlC++Cf++++Hk+H+yk++ s+gggfCdCGd eAw++g+ Ckk+
   Q: 71   LCGKVFKGGETTYSCRDCAIDPTCVLCMDCFQNSIHKNHRYKMNSSSGGGFCDCGDVEAWKNGPACKKH 139
           8******************************************************************99 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

WQDCPDLKYE VYRHLAQYVP KIYCTRAEAK PVEEEELVQG ALLRPLEWYL FGEDPQVGLE 60
KLIQSSGSSE LCGKVFKGGE TTYSCRDCAI DPTCVLCMDC FQNSIHKNHR YKMNSSSGGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCAAGACT GCCCCGACCT AAAGTATGAA GTCTACCGGC ACCTGGCACA GTACGTGCCG 60
AAAATATACT GCACGAGGGC AGAGGCAAAG CCAGTGGAGG AGGAAGAGCT GGTTCAGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0030163--P:protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	61.30	0.00e+00	2138.00
IUUC-Atr-002501	Amborella trichopoda	30.25	3.00e-26	115.00
IUUC-Apl-004160	Anas platyrhynchos	63.57	0.00e+00	2217.00
IUUC-Aca-004982	Anolis carolinensis	61.40	0.00e+00	2145.00
IUUC-Ago-007752	Ashbya gossypii	22.46	1.00e-21	99.80
IUUC-Acl-008055	Aspergillus clavatus	26.71	2.00e-38	155.00
IUUC-Afl-008479	Aspergillus flavus	22.90	6.00e-43	170.00
IUUC-Afu-008929	Aspergillus fumigatus	22.97	2.00e-47	185.00
IUUC-Ani-009334	Aspergillus nidulans	23.36	5.00e-46	181.00
IUUC-Ang-009550	Aspergillus niger	23.56	8.00e-42	167.00
IUUC-Aor-010124	Aspergillus oryzae	22.95	4.00e-43	171.00
IUUC-Ate-010550	Aspergillus terreus	23.31	2.00e-47	186.00
IUUC-Ame-011231	Astyanax mexicanus	59.55	0.00e+00	1917.00
IUUC-Bgr-011999	Blumeria graminis	22.10	2.00e-40	162.00
IUUC-Bta-012347	Bos taurus	61.83	0.00e+00	2133.00
IUUC-Bci-013834	Botrytis cinerea	22.87	3.00e-39	158.00
IUUC-Cel-018476	Caenorhabditis elegans	32.50	2.00e-71	265.00
IUUC-Cja-018911	Callithrix jacchus	60.56	0.00e+00	2116.00
IUUC-Cfa-020991	Canis familiaris	62.15	0.00e+00	2160.00
IUUC-Cpo-021448	Cavia porcellus	60.39	0.00e+00	2127.00
IUUC-Csa-024255	Chlorocebus sabaeus	62.54	0.00e+00	1778.00
IUUC-Cho-024550	Choloepus hoffmanni	49.51	0.00e+00	1597.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	23.26	6.00e-46	180.00
IUUC-Cne-026823	Cryptococcus neoformans	22.42	2.00e-47	184.00
IUUC-Dno-029427	Dasypus novemcinctus	61.49	0.00e+00	2117.00
IUUC-Dor-031073	Dipodomys ordii	58.55	0.00e+00	967.00
IUUC-Dse-031531	Dothistroma septosporum	22.92	3.00e-39	158.00
IUUC-Dme-031910	Drosophila melanogaster	32.13	0.00e+00	637.00
IUUC-Ete-032318	Echinops telfairi	47.17	0.00e+00	751.00
IUUC-Eca-033348	Equus caballus	61.33	0.00e+00	2022.00
IUUC-Eeu-034664	Erinaceus europaeus	56.37	0.00e+00	1934.00
IUUC-Fca-035604	Felis catus	57.82	0.00e+00	1947.00
IUUC-Fal-037333	Ficedula albicollis	64.14	0.00e+00	2203.00
IUUC-Fox-037984	Fusarium oxysporum	24.50	3.00e-33	138.00
IUUC-Fso-038463	Fusarium solani	24.54	5.00e-38	154.00
IUUC-Gmo-039363	Gadus morhua	55.87	0.00e+00	1627.00
IUUC-Gga-040486	Gallus gallus	62.97	0.00e+00	2136.00
IUUC-Gac-041985	Gasterosteus aculeatus	57.63	0.00e+00	1707.00
IUUC-Ggo-044704	Gorilla gorilla	57.00	0.00e+00	1654.00
IUUC-Hsa-046753	Homo sapiens	61.46	0.00e+00	2155.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	61.92	0.00e+00	2144.00
IUUC-Kpa-049088	Komagataella pastoris	22.35	1.00e-31	132.00
IUUC-Loc-052624	Lepisosteus oculatus	64.70	0.00e+00	2124.00
IUUC-Lma-053059	Leptosphaeria maculans	24.11	9.00e-42	166.00
IUUC-Laf-053857	Loxodonta africana	61.65	0.00e+00	2175.00
IUUC-Mcc-054873	Macaca mulatta	61.92	0.00e+00	2138.00
IUUC-Meu-056858	Macropus eugenii	50.00	0.00e+00	778.00
IUUC-Mla-058963	Melampsora laricipopulina	25.34	2.00e-49	191.00
IUUC-Mga-059917	Meleagris gallopavo	63.66	0.00e+00	2228.00
IUUC-Mvi-060535	Microbotryum violaceum	22.13	3.00e-48	188.00
IUUC-Mmr-061128	Microcebus murinus	58.97	0.00e+00	1987.00
IUUC-Mdo-062306	Monodelphis domestica	63.17	0.00e+00	2180.00
IUUC-Mmu-063389	Mus musculus	61.68	0.00e+00	2152.00
IUUC-Mpu-065983	Mustela putorius furo	61.88	0.00e+00	2169.00
IUUC-Mlu-068013	Myotis lucifugus	60.49	0.00e+00	2102.00
IUUC-Nfi-068403	Neosartorya fischeri	23.08	2.00e-48	189.00
IUUC-Nle-070031	Nomascus leucogenys	61.63	0.00e+00	2159.00
IUUC-Opr-070551	Ochotona princeps	48.01	0.00e+00	881.00
IUUC-Ont-072035	Oreochromis niloticus	59.10	0.00e+00	1953.00
IUUC-Ocu-074930	Oryctolagus cuniculus	60.49	0.00e+00	2126.00
IUUC-Ome-081738	Oryza meridionalis	37.31	9.00e-14	73.60
IUUC-Osa-086106	Oryza sativa	38.06	6.00e-14	72.80
IUUC-Ola-086683	Oryzias latipes	58.40	0.00e+00	1920.00
IUUC-Oga-088017	Otolemur garnettii	58.75	0.00e+00	2013.00
IUUC-Oar-089557	Ovis aries	61.34	0.00e+00	2131.00
IUUC-Ptr-091366	Pan troglodytes	60.88	0.00e+00	2130.00
IUUC-Pan-092184	Papio anubis	61.92	0.00e+00	2138.00
IUUC-Psi-093720	Pelodiscus sinensis	63.13	0.00e+00	2127.00
IUUC-Pno-094877	Phaeosphaeria nodorum	22.79	3.00e-23	105.00
IUUC-Pfo-097124	Poecilia formosa	59.13	0.00e+00	1940.00
IUUC-Pab-098586	Pongo abelii	61.72	0.00e+00	2154.00
IUUC-Pop-099184	Populus trichocarpa	40.74	2.00e-14	73.60
IUUC-Pca-100673	Procavia capensis	56.46	0.00e+00	1129.00
IUUC-Pva-102724	Pteropus vampyrus	63.34	0.00e+00	1557.00
IUUC-Pgr-103372	Puccinia graminis	24.20	9.00e-51	196.00
IUUC-Ptt-103878	Puccinia triticina	24.64	9.00e-45	176.00
IUUC-Pte-104174	Pyrenophora teres	23.21	3.00e-43	171.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	23.08	4.00e-43	171.00
IUUC-Sha-106993	Sarcophilus harrisii	62.58	0.00e+00	2192.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	22.99	1.00e-42	169.00
IUUC-Spo-108183	Schizosaccharomyces pombe	23.40	2.00e-62	235.00
IUUC-Sar-113447	Sorex araneus	60.56	0.00e+00	1473.00
IUUC-Sbi-114577	Sorghum bicolor	27.67	4.00e-26	114.00
IUUC-Sre-115045	Sporisorium reilianum	27.04	3.00e-45	178.00
IUUC-Ssc-115768	Sus scrofa	59.65	0.00e+00	1950.00
IUUC-Tgu-116949	Taeniopygia guttata	62.12	0.00e+00	2120.00
IUUC-Tru-117782	Takifugu rubripes	57.09	0.00e+00	1925.00
IUUC-Tsy-119177	Tarsius syrichta	55.02	0.00e+00	1420.00
IUUC-Tni-120884	Tetraodon nigroviridis	52.72	0.00e+00	1711.00
IUUC-Tre-122137	Trichoderma reesei	24.40	4.00e-55	211.00
IUUC-Tvi-122272	Trichoderma virens	23.35	2.00e-48	188.00
IUUC-Tme-127156	Tuber melanosporum	21.63	5.00e-41	164.00
IUUC-Tbe-128088	Tupaia belangeri	53.35	0.00e+00	780.00
IUUC-Ttr-129062	Tursiops truncatus	58.51	0.00e+00	2008.00
IUUC-Uma-129344	Ustilago maydis	27.17	1.00e-45	179.00
IUUC-Vda-129778	Verticillium dahliae	24.05	2.00e-38	155.00
IUUC-Vvi-130900	Vitis vinifera	36.60	9.00e-15	74.30
IUUC-Xtr-132244	Xenopus tropicalis	54.22	0.00e+00	1867.00
IUUC-Xma-134112	Xiphophorus maculatus	59.06	0.00e+00	1953.00
IUUC-Yli-134662	Yarrowia lipolytica	24.75	6.00e-29	124.00
IUUC-Zma-135553	Zea mays	37.69	5.00e-13	71.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence