iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053563

UUCD1 version

UUC-LoA-00186

Ensembl Protein ID

ENSLAFP00000004500.3

UniProt Accession

G3SW38; G3SW38_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005374.3	ENSLAFT00000005374.3	ENSLAFP00000004500.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	27.47	3.00e-30	129.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	91.00	0.00e+00	750.00	IUUC-Hsa-046512
E3 adaptor/Cullin RING/SCF/F-box	55.53	2.00e-117	420.00	IUUC-Ots-000025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

FCRKHLQEIP DQSSNVTTSF TWGWDSSKTS ELLSGMGVSA LEKEEVDSEN IPQELLSSLS 60
HPQSPPRKRL KSKGNDKDFV IVRRPKLNRE NFPGVSWDTL PDELLLGIFS CLCLPELLKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTGCAGGA AACACCTCCA GGAGATTCCG GACCAAAGTA GCAACGTTAC CACCAGTTTC 60
ACGTGGGGAT GGGATTCTAG CAAGACTTCA GAACTGCTCT CAGGCATGGG AGTCTCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	91.94	0.00e+00	761.00
IUUC-Atr-002711	Amborella trichopoda	24.22	1.00e-09	58.50
IUUC-Apl-003453	Anas platyrhynchos	67.47	4.00e-118	417.00
IUUC-Aca-005185	Anolis carolinensis	61.68	1.00e-141	496.00
IUUC-Ame-010665	Astyanax mexicanus	47.10	2.00e-92	332.00
IUUC-Bta-013450	Bos taurus	90.05	0.00e+00	781.00
IUUC-Cel-018410	Caenorhabditis elegans	27.16	6.00e-28	118.00
IUUC-Cja-019834	Callithrix jacchus	90.05	0.00e+00	774.00
IUUC-Cfa-020401	Canis familiaris	92.42	0.00e+00	794.00
IUUC-Cpo-022183	Cavia porcellus	89.86	0.00e+00	778.00
IUUC-Csa-023418	Chlorocebus sabaeus	90.76	0.00e+00	777.00
IUUC-Cho-024412	Choloepus hoffmanni	88.64	3.00e-180	624.00
IUUC-Cin-025248	Ciona intestinalis	29.68	5.00e-43	168.00
IUUC-Csv-026189	Ciona savignyi	30.33	1.00e-37	150.00
IUUC-Dre-028032	Danio rerio	49.46	1.00e-106	380.00
IUUC-Dno-029222	Dasypus novemcinctus	91.47	0.00e+00	786.00
IUUC-Dor-030505	Dipodomys ordii	85.23	2.00e-168	585.00
IUUC-Dme-031972	Drosophila melanogaster	33.43	8.00e-52	197.00
IUUC-Ete-032234	Echinops telfairi	86.30	2.00e-119	422.00
IUUC-Eca-033944	Equus caballus	92.42	0.00e+00	795.00
IUUC-Eeu-035008	Erinaceus europaeus	84.23	4.00e-120	424.00
IUUC-Fca-035412	Felis catus	91.47	0.00e+00	786.00
IUUC-Fal-037337	Ficedula albicollis	64.54	6.00e-143	500.00
IUUC-Gmo-038934	Gadus morhua	43.58	1.00e-41	163.00
IUUC-Gga-041152	Gallus gallus	67.63	3.00e-160	558.00
IUUC-Gac-041819	Gasterosteus aculeatus	44.50	3.00e-78	285.00
IUUC-Ggo-045479	Gorilla gorilla	90.34	0.00e+00	645.00
IUUC-Hsa-046512	Homo sapiens	91.00	0.00e+00	780.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	91.15	0.00e+00	755.00
IUUC-Lch-050115	Latimeria chalumnae	57.52	6.00e-136	476.00
IUUC-Loc-052554	Lepisosteus oculatus	49.41	1.00e-107	383.00
IUUC-Mcc-055143	Macaca mulatta	90.80	0.00e+00	783.00
IUUC-Meu-056593	Macropus eugenii	56.16	9.00e-105	373.00
IUUC-Mga-060084	Meleagris gallopavo	60.15	2.00e-84	305.00
IUUC-Mmr-060660	Microcebus murinus	94.08	0.00e+00	808.00
IUUC-Mdo-062363	Monodelphis domestica	70.55	2.00e-163	568.00
IUUC-Mmu-063287	Mus musculus	84.83	0.00e+00	746.00
IUUC-Mpu-065791	Mustela putorius furo	91.47	0.00e+00	788.00
IUUC-Mlu-067714	Myotis lucifugus	87.59	0.00e+00	743.00
IUUC-Nle-069823	Nomascus leucogenys	91.47	0.00e+00	784.00
IUUC-Opr-071046	Ochotona princeps	72.44	1.00e-102	366.00
IUUC-Ont-071820	Oreochromis niloticus	45.57	1.00e-68	253.00
IUUC-Ocu-074868	Oryctolagus cuniculus	91.71	0.00e+00	790.00
IUUC-Oba-075104	Oryza barthii	24.33	8.00e-06	46.60
IUUC-Ola-086608	Oryzias latipes	46.74	5.00e-76	278.00
IUUC-Oga-089044	Otolemur garnettii	92.42	0.00e+00	794.00
IUUC-Oar-089650	Ovis aries	89.81	0.00e+00	775.00
IUUC-Ptr-090743	Pan troglodytes	91.00	0.00e+00	781.00
IUUC-Pan-092501	Papio anubis	90.76	0.00e+00	778.00
IUUC-Psi-094032	Pelodiscus sinensis	67.78	2.00e-161	561.00
IUUC-Ppa-095537	Physcomitrella patens	25.83	3.00e-11	63.90
IUUC-Pfo-097279	Poecilia formosa	47.16	2.00e-67	249.00
IUUC-Pab-097821	Pongo abelii	91.19	0.00e+00	648.00
IUUC-Pca-100100	Procavia capensis	95.74	0.00e+00	644.00
IUUC-Pva-103181	Pteropus vampyrus	91.48	4.00e-180	624.00
IUUC-Rno-105091	Rattus norvegicus	86.63	0.00e+00	753.00
IUUC-Sha-107226	Sarcophilus harrisii	71.12	2.00e-167	581.00
IUUC-Smo-109321	Selaginella moellendorffii	25.30	2.00e-11	65.10
IUUC-Ssc-115665	Sus scrofa	92.89	0.00e+00	798.00
IUUC-Tgu-116982	Taeniopygia guttata	64.07	2.00e-139	488.00
IUUC-Tru-118276	Takifugu rubripes	46.56	7.00e-77	280.00
IUUC-Tsy-119074	Tarsius syrichta	92.61	0.00e+00	662.00
IUUC-Tni-120702	Tetraodon nigroviridis	48.92	8.00e-52	197.00
IUUC-Tbe-127990	Tupaia belangeri	90.27	2.00e-155	541.00
IUUC-Ttr-128661	Tursiops truncatus	76.15	2.00e-109	389.00
IUUC-Vvi-131526	Vitis vinifera	25.00	2.00e-10	61.20
IUUC-Xtr-132166	Xenopus tropicalis	57.45	2.00e-126	445.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence