iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041643

Ensembl Protein ID

ENSGACP00000022183.1

UniProt Accession

G3PX44; G3PX44_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000016802.1	ENSGACT00000022225.1	ENSGACP00000022183.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.60e-14	52.9	90	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 90   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 147
           68899************************.***********..79999**********997 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

PVWRVPAAAW HRALMGQQPG KFVGDQRRPS LPAFIRGGRR ESSRHGTQPC NVFVVHEALQ 60
RPDFESPGLT EAARWNSKEN LLAGPSENDP NLFVALYDFV ASGDNTLSIT KGEKLRVLGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGTTTGGA GAGTCCCGGC TGCGGCCTGG CACCGTGCCC TTATGGGGCA GCAGCCGGGG 60
AAGTTTGTCG GGGACCAGAG GAGACCTAGT CTGCCGGCCT TCATCAGAGG TGGAAGGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	73.65	0.00e+00	1146.00
IUUC-Apl-003452	Anas platyrhynchos	76.80	0.00e+00	1083.00
IUUC-Aca-005312	Anolis carolinensis	74.58	0.00e+00	1099.00
IUUC-Ame-011903	Astyanax mexicanus	79.13	0.00e+00	1232.00
IUUC-Bta-012351	Bos taurus	75.49	0.00e+00	1090.00
IUUC-Cja-019491	Callithrix jacchus	67.32	0.00e+00	1315.00
IUUC-Cfa-021256	Canis familiaris	75.44	0.00e+00	1160.00
IUUC-Cpo-022046	Cavia porcellus	77.67	0.00e+00	1165.00
IUUC-Csa-023046	Chlorocebus sabaeus	67.46	0.00e+00	1273.00
IUUC-Dre-028190	Danio rerio	71.70	0.00e+00	1343.00
IUUC-Dno-029853	Dasypus novemcinctus	73.29	0.00e+00	1164.00
IUUC-Dor-030635	Dipodomys ordii	69.19	0.00e+00	1021.00
IUUC-Dme-032098	Drosophila melanogaster	74.89	0.00e+00	767.00
IUUC-Eca-033720	Equus caballus	72.91	0.00e+00	1101.00
IUUC-Eeu-035173	Erinaceus europaeus	72.16	0.00e+00	1084.00
IUUC-Fca-035967	Felis catus	75.88	0.00e+00	1145.00
IUUC-Fal-036723	Ficedula albicollis	66.70	0.00e+00	1246.00
IUUC-Gmo-039550	Gadus morhua	86.01	0.00e+00	1326.00
IUUC-Gga-040481	Gallus gallus	75.72	0.00e+00	1088.00
IUUC-Ggo-045299	Gorilla gorilla	67.23	0.00e+00	1314.00
IUUC-Hsa-047033	Homo sapiens	91.89	4.00e-36	142.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	75.37	0.00e+00	1106.00
IUUC-Lch-050530	Latimeria chalumnae	66.95	0.00e+00	1319.00
IUUC-Loc-052430	Lepisosteus oculatus	84.59	0.00e+00	1026.00
IUUC-Laf-053609	Loxodonta africana	66.81	0.00e+00	1289.00
IUUC-Mcc-055654	Macaca mulatta	67.20	0.00e+00	1331.00
IUUC-Meu-056488	Macropus eugenii	60.39	0.00e+00	1110.00
IUUC-Mga-059270	Meleagris gallopavo	76.77	0.00e+00	1097.00
IUUC-Mmr-060593	Microcebus murinus	73.82	0.00e+00	1090.00
IUUC-Mdo-062227	Monodelphis domestica	78.83	0.00e+00	1107.00
IUUC-Mmu-064002	Mus musculus	76.58	0.00e+00	1194.00
IUUC-Mac-065247	Musa acuminata	30.80	2.00e-22	101.00
IUUC-Mpu-066197	Mustela putorius furo	75.38	0.00e+00	1145.00
IUUC-Mlu-067255	Myotis lucifugus	74.00	0.00e+00	1088.00
IUUC-Nle-069977	Nomascus leucogenys	71.63	0.00e+00	1022.00
IUUC-Opr-070327	Ochotona princeps	69.42	0.00e+00	959.00
IUUC-Ont-072307	Oreochromis niloticus	80.14	0.00e+00	1635.00
IUUC-Oan-073100	Ornithorhynchus anatinus	76.21	0.00e+00	1112.00
IUUC-Ocu-074892	Oryctolagus cuniculus	72.45	0.00e+00	1003.00
IUUC-Ola-087389	Oryzias latipes	76.24	0.00e+00	1582.00
IUUC-Oga-088145	Otolemur garnettii	66.11	0.00e+00	1233.00
IUUC-Oar-090432	Ovis aries	75.58	0.00e+00	1078.00
IUUC-Ptr-090800	Pan troglodytes	67.80	0.00e+00	1323.00
IUUC-Psi-093078	Pelodiscus sinensis	68.14	0.00e+00	1285.00
IUUC-Pma-094420	Petromyzon marinus	76.52	0.00e+00	867.00
IUUC-Pfo-096979	Poecilia formosa	78.82	0.00e+00	1526.00
IUUC-Pca-100874	Procavia capensis	94.21	0.00e+00	714.00
IUUC-Pva-102415	Pteropus vampyrus	73.83	0.00e+00	1152.00
IUUC-Rno-105682	Rattus norvegicus	76.80	0.00e+00	1194.00
IUUC-Sha-106711	Sarcophilus harrisii	74.35	0.00e+00	1112.00
IUUC-Ssc-115472	Sus scrofa	77.63	0.00e+00	1155.00
IUUC-Tgu-117037	Taeniopygia guttata	67.40	0.00e+00	1310.00
IUUC-Tru-118324	Takifugu rubripes	74.42	0.00e+00	1537.00
IUUC-Tsy-119216	Tarsius syrichta	91.39	0.00e+00	1034.00
IUUC-Tni-119950	Tetraodon nigroviridis	74.52	0.00e+00	1514.00
IUUC-Ttr-128209	Tursiops truncatus	68.11	0.00e+00	1324.00
IUUC-Xtr-132477	Xenopus tropicalis	69.51	0.00e+00	977.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence