iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000014093.1	ENSONIT00000017729.1	ENSONIP00000017714.1
ENSONIG00000014093.1	ENSONIT00000017730.1	ENSONIP00000017715.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.20e-14	51.6	76	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 76   PNLFVALYDFVASGDNTLSITKGEKLRVL-CYNHNGEWCEA--QTKNGQGWVPSNYITPVN 133
           68899************************.***********..79999**********997 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGQQPGKLVG DQRRPSLPAF IKGSKKESSR HGNQPCNVFA VHEALQKPEI EGQGLTEAAR 60
WNSKENLLAG PSENDPNLFV ALYDFVASGD NTLSITKGEK LRVLCYNHNG EWCEAQTKNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGCGTACT CTCTCTGCCT CAGCGTGGCT GCAGTGTTGT TGCTCTTCCA GCACAACAAA 60
ACCTTTGCTC TTGTCCTCCT GTGCTAGTCC ACGCACGCAC GTGACGTCGT ACGTCGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000527	Aegilops tauschii	28.36	6.00e-19	89.40
IUUC-Aml-001550	Ailuropoda melanoleuca	70.63	0.00e+00	1119.00
IUUC-Apl-003452	Anas platyrhynchos	66.25	0.00e+00	1209.00
IUUC-Aca-005312	Anolis carolinensis	72.79	0.00e+00	1043.00
IUUC-Ame-011903	Astyanax mexicanus	78.09	0.00e+00	1203.00
IUUC-Bta-012351	Bos taurus	69.93	0.00e+00	1068.00
IUUC-Cja-019491	Callithrix jacchus	66.49	0.00e+00	1285.00
IUUC-Cfa-021256	Canis familiaris	66.72	0.00e+00	1281.00
IUUC-Cpo-022046	Cavia porcellus	69.74	0.00e+00	1123.00
IUUC-Csa-023046	Chlorocebus sabaeus	65.63	0.00e+00	1245.00
IUUC-Dre-028190	Danio rerio	70.96	0.00e+00	1324.00
IUUC-Dno-029853	Dasypus novemcinctus	65.89	0.00e+00	1276.00
IUUC-Dor-030635	Dipodomys ordii	65.32	0.00e+00	980.00
IUUC-Dme-032098	Drosophila melanogaster	74.25	0.00e+00	761.00
IUUC-Eca-033720	Equus caballus	69.83	0.00e+00	1059.00
IUUC-Eeu-035173	Erinaceus europaeus	66.41	0.00e+00	1040.00
IUUC-Fca-035967	Felis catus	65.81	0.00e+00	1264.00
IUUC-Fal-036723	Ficedula albicollis	87.00	0.00e+00	1005.00
IUUC-Gmo-039550	Gadus morhua	82.20	0.00e+00	1218.00
IUUC-Gga-040481	Gallus gallus	84.26	0.00e+00	1004.00
IUUC-Gac-041643	Gasterosteus aculeatus	79.52	0.00e+00	1607.00
IUUC-Ggo-045299	Gorilla gorilla	65.64	0.00e+00	1293.00
IUUC-Hsa-047033	Homo sapiens	87.84	4.00e-34	135.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	63.83	0.00e+00	1210.00
IUUC-Lch-050530	Latimeria chalumnae	66.81	0.00e+00	1279.00
IUUC-Loc-052430	Lepisosteus oculatus	57.00	0.00e+00	1040.00
IUUC-Laf-053609	Loxodonta africana	69.81	0.00e+00	1118.00
IUUC-Mcc-055654	Macaca mulatta	65.51	0.00e+00	1308.00
IUUC-Meu-056488	Macropus eugenii	59.98	0.00e+00	1072.00
IUUC-Mga-059270	Meleagris gallopavo	66.04	0.00e+00	1206.00
IUUC-Mmr-060593	Microcebus murinus	68.78	0.00e+00	1057.00
IUUC-Mdo-062227	Monodelphis domestica	81.38	0.00e+00	1066.00
IUUC-Mmu-064002	Mus musculus	65.89	0.00e+00	1298.00
IUUC-Mpu-066197	Mustela putorius furo	69.56	0.00e+00	1103.00
IUUC-Mlu-067255	Myotis lucifugus	65.27	0.00e+00	1202.00
IUUC-Nle-069977	Nomascus leucogenys	61.02	0.00e+00	1137.00
IUUC-Opr-070327	Ochotona princeps	60.39	0.00e+00	1062.00
IUUC-Oan-073100	Ornithorhynchus anatinus	70.92	0.00e+00	1078.00
IUUC-Ocu-074892	Oryctolagus cuniculus	71.20	0.00e+00	963.00
IUUC-Ola-087389	Oryzias latipes	75.89	0.00e+00	1518.00
IUUC-Oga-088145	Otolemur garnettii	65.86	0.00e+00	1215.00
IUUC-Oar-090432	Ovis aries	74.48	0.00e+00	1037.00
IUUC-Ptr-090800	Pan troglodytes	66.12	0.00e+00	1303.00
IUUC-Psi-093078	Pelodiscus sinensis	67.17	0.00e+00	1269.00
IUUC-Pma-094420	Petromyzon marinus	76.74	0.00e+00	864.00
IUUC-Pfo-096979	Poecilia formosa	79.39	0.00e+00	1515.00
IUUC-Pca-100874	Procavia capensis	93.16	0.00e+00	708.00
IUUC-Pva-102415	Pteropus vampyrus	73.06	0.00e+00	1114.00
IUUC-Rno-105682	Rattus norvegicus	65.66	0.00e+00	1303.00
IUUC-Sha-106711	Sarcophilus harrisii	70.49	0.00e+00	1066.00
IUUC-Ssc-115472	Sus scrofa	74.15	0.00e+00	1108.00
IUUC-Tgu-117037	Taeniopygia guttata	67.04	0.00e+00	1286.00
IUUC-Tru-118324	Takifugu rubripes	72.11	0.00e+00	1467.00
IUUC-Tsy-119216	Tarsius syrichta	89.02	0.00e+00	1022.00
IUUC-Tni-119950	Tetraodon nigroviridis	72.86	0.00e+00	1434.00
IUUC-Tca-121389	Theobroma cacao	29.92	1.00e-22	102.00
IUUC-Tae-122912	Triticum aestivum	27.74	2.00e-19	91.70
IUUC-Tur-126227	Triticum urartu	27.41	1.00e-17	85.10
IUUC-Ttr-128209	Tursiops truncatus	67.16	0.00e+00	1300.00
IUUC-Xtr-132477	Xenopus tropicalis	66.87	0.00e+00	928.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence