iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004635

UUCD1 version

UUC-AnC-00251

Ensembl Protein ID

ENSACAP00000000869.3

UniProt Accession

H9G4F3; H9G4F3_ANOCA

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Gene Name

KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000837.3	ENSACAT00000000896.3	ENSACAP00000000869.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-41	138.1	147	182
UBD/Beta-Prp	1.40e-60	205.0	12	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH+  v+cl+f +d + l+s+sdD+t+k+WDl  g+
   Q: 147  GHSQAVRCLRFsPDgKWLASSSDDHTVKLWDLAAGK 182
           8***********999****************98876 PP

UBD/Beta-Prp

   S: 42   gkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
            ++l+++  h++ v+++ + +++  +l+tg+eD  +++w+++++ c+++l+gh+  v s++++ + + +v+Gs+   ir+wdle  + l
   Q: 12   AWKLQEITAHSSSVSSLVLGKSSGrLLATGGEDCRVNIWSVNKPNCIMSLTGHTTPVESVKINTNEELIVAGSQSGSIRIWDLEAAKIL 100
           5567889999999999988555444**************************************************************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
           + tl gh++ ++++ +hp+g  ++sGs D+ ++lWd++++ ++ + +g h ++v++l f+++gk l+s s+d tvklwdl +g+++ ++
   Q: 101  R-TLMGHKANICSLDFHPFGGFVASGSMDTNIKLWDVRRKGCVFRYKG-HSQAVRCLRFSPDGKWLASSSDDHTVKLWDLAAGKIMFEF 187
           9.********************************************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlql 262
            ght +v++v+f+pn+ +l+sgssD+ ir+Wdl++ +++++++ 
   Q: 188  AGHTGPVNMVEFHPNEYLLASGSSDRMIRFWDLEKFQVVSCIEE 231
           ***********************************999999876 PP

Organism

Anolis carolinensis

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MMATAAVATK TAWKLQEITA HSSSVSSLVL GKSSGRLLAT GGEDCRVNIW SVNKPNCIMS 60
LTGHTTPVES VKINTNEELI VAGSQSGSIR IWDLEAAKIL RTLMGHKANI CSLDFHPFGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATTATATA CATATACACA TATAAACTAC AATATAAATA TAATACAATA TATTATTCAA 60
TATAAATATT TGAATATATT TATAATTTAA TAAAATATAT AACAATAATA TAGTGTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR027295--Quinoprotein_ADH-like_fam
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030424--C:axon
GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0000922--C:spindle pole
GO:0008568--F:microtubule-severing ATPase activity
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0007067--P:mitotic nuclear division
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0031117--P:positive regulation of microtubule depolymerization

KEGG

acs:100567820

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	43.87	2.00e-77	284.00
IUUC-Aml-002187	Ailuropoda melanoleuca	75.98	0.00e+00	900.00
IUUC-Atr-002899	Amborella trichopoda	52.74	1.00e-93	337.00
IUUC-Apl-003305	Anas platyrhynchos	80.26	0.00e+00	1029.00
IUUC-Aly-005711	Arabidopsis lyrata	50.54	2.00e-93	337.00
IUUC-Ath-007606	Arabidopsis thaliana	50.54	2.00e-93	336.00
IUUC-Ame-010870	Astyanax mexicanus	58.02	4.00e-94	337.00
IUUC-Bta-012527	Bos taurus	79.85	0.00e+00	981.00
IUUC-Bdi-014652	Brachypodium distachyon	51.26	4.00e-94	339.00
IUUC-Bol-015242	Brassica oleracea	48.55	4.00e-92	332.00
IUUC-Bra-017390	Brassica rapa	50.54	1.00e-92	334.00
IUUC-Cja-019706	Callithrix jacchus	78.80	0.00e+00	904.00
IUUC-Cfa-020139	Canis familiaris	67.56	2.00e-173	602.00
IUUC-Cpo-021710	Cavia porcellus	81.26	0.00e+00	962.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	41.64	6.00e-66	245.00
IUUC-Csa-023546	Chlorocebus sabaeus	79.72	0.00e+00	885.00
IUUC-Cin-025156	Ciona intestinalis	42.43	7.00e-146	510.00
IUUC-Csv-025962	Ciona savignyi	48.20	2.00e-79	288.00
IUUC-Dre-028215	Danio rerio	62.37	0.00e+00	790.00
IUUC-Dno-029314	Dasypus novemcinctus	80.03	0.00e+00	930.00
IUUC-Dor-030482	Dipodomys ordii	80.34	0.00e+00	992.00
IUUC-Dme-032188	Drosophila melanogaster	40.50	1.00e-55	211.00
IUUC-Eca-034143	Equus caballus	79.26	0.00e+00	960.00
IUUC-Fca-035924	Felis catus	79.57	0.00e+00	957.00
IUUC-Fal-037387	Ficedula albicollis	81.60	0.00e+00	998.00
IUUC-Gmo-038692	Gadus morhua	65.37	1.00e-138	486.00
IUUC-Gga-040597	Gallus gallus	81.26	0.00e+00	1014.00
IUUC-Gac-042004	Gasterosteus aculeatus	61.13	0.00e+00	758.00
IUUC-Gma-044134	Glycine max	50.85	3.00e-91	329.00
IUUC-Ggo-044761	Gorilla gorilla	79.72	0.00e+00	908.00
IUUC-Hsa-045698	Homo sapiens	79.72	0.00e+00	926.00
IUUC-Hvu-047649	Hordeum vulgare	49.35	2.00e-94	340.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	79.11	0.00e+00	938.00
IUUC-Lch-049674	Latimeria chalumnae	67.51	0.00e+00	853.00
IUUC-Lpe-051554	Leersia perrieri	51.99	6.00e-95	342.00
IUUC-Loc-052623	Lepisosteus oculatus	67.45	0.00e+00	856.00
IUUC-Laf-054587	Loxodonta africana	80.03	0.00e+00	949.00
IUUC-Mcc-055851	Macaca mulatta	79.72	0.00e+00	908.00
IUUC-Meu-056704	Macropus eugenii	80.95	0.00e+00	1011.00
IUUC-Mtr-058053	Medicago truncatula	50.90	8.00e-95	341.00
IUUC-Mga-059608	Meleagris gallopavo	81.29	0.00e+00	1011.00
IUUC-Mmr-061154	Microcebus murinus	80.34	0.00e+00	928.00
IUUC-Mdo-062365	Monodelphis domestica	76.61	0.00e+00	936.00
IUUC-Mmu-063754	Mus musculus	81.60	0.00e+00	954.00
IUUC-Mac-065100	Musa acuminata	51.19	2.00e-91	330.00
IUUC-Mpu-066245	Mustela putorius furo	80.67	0.00e+00	923.00
IUUC-Mlu-067692	Myotis lucifugus	78.56	0.00e+00	949.00
IUUC-Nle-070051	Nomascus leucogenys	79.94	0.00e+00	898.00
IUUC-Opr-070855	Ochotona princeps	81.11	0.00e+00	956.00
IUUC-Ont-071883	Oreochromis niloticus	59.06	0.00e+00	775.00
IUUC-Oan-073293	Ornithorhynchus anatinus	81.41	0.00e+00	912.00
IUUC-Ocu-074644	Oryctolagus cuniculus	80.18	0.00e+00	964.00
IUUC-Oba-075448	Oryza barthii	51.62	1.00e-94	341.00
IUUC-Obr-076385	Oryza brachyantha	51.26	2.00e-94	340.00
IUUC-Ogl-077427	Oryza glaberrima	51.62	5.00e-95	342.00
IUUC-Ogu-078062	Oryza glumaepatula	49.64	1.00e-89	323.00
IUUC-Oin-079811	Oryza indica	51.09	6.00e-93	335.00
IUUC-Olo-080245	Oryza longistaminata	51.09	7.00e-93	335.00
IUUC-Ome-081239	Oryza meridionalis	51.27	1.00e-92	334.00
IUUC-Oni-082640	Oryza nivara	51.62	1.00e-94	341.00
IUUC-Opu-083748	Oryza punctata	51.99	3.00e-95	342.00
IUUC-Oru-084609	Oryza rufipogon	51.62	1.00e-94	341.00
IUUC-Osa-085801	Oryza sativa	49.46	5.00e-90	325.00
IUUC-Ola-087483	Oryzias latipes	56.77	7.00e-168	583.00
IUUC-Oga-087964	Otolemur garnettii	79.72	0.00e+00	968.00
IUUC-Oar-089483	Ovis aries	77.86	0.00e+00	931.00
IUUC-Ptr-091387	Pan troglodytes	79.88	0.00e+00	927.00
IUUC-Pan-092623	Papio anubis	79.72	0.00e+00	908.00
IUUC-Psi-093830	Pelodiscus sinensis	85.60	0.00e+00	1036.00
IUUC-Pma-094135	Petromyzon marinus	45.10	8.00e-39	153.00
IUUC-Ppa-095379	Physcomitrella patens	53.42	3.00e-88	320.00
IUUC-Pfo-096755	Poecilia formosa	59.44	0.00e+00	769.00
IUUC-Pab-097564	Pongo abelii	77.37	0.00e+00	781.00
IUUC-Pop-099149	Populus trichocarpa	52.20	3.00e-96	346.00
IUUC-Pca-100357	Procavia capensis	88.00	3.00e-105	375.00
IUUC-Ppe-101237	Prunus persica	51.19	2.00e-94	340.00
IUUC-Pva-102397	Pteropus vampyrus	75.88	0.00e+00	883.00
IUUC-Rno-105349	Rattus norvegicus	80.18	0.00e+00	990.00
IUUC-Smo-109409	Selaginella moellendorffii	52.90	4.00e-92	332.00
IUUC-Sit-110360	Setaria italica	52.35	3.00e-95	343.00
IUUC-Sly-111307	Solanum lycopersicum	52.71	3.00e-92	332.00
IUUC-Stu-112462	Solanum tuberosum	52.19	5.00e-90	324.00
IUUC-Sar-112953	Sorex araneus	71.05	5.00e-94	338.00
IUUC-Sbi-114389	Sorghum bicolor	47.65	5.00e-88	318.00
IUUC-Ssc-115949	Sus scrofa	76.05	0.00e+00	719.00
IUUC-Tgu-117461	Taeniopygia guttata	80.24	0.00e+00	1015.00
IUUC-Tru-117865	Takifugu rubripes	59.37	0.00e+00	759.00
IUUC-Tsy-119036	Tarsius syrichta	62.90	1.00e-54	206.00
IUUC-Tni-120903	Tetraodon nigroviridis	61.77	0.00e+00	748.00
IUUC-Tca-121185	Theobroma cacao	51.19	2.00e-93	337.00
IUUC-Tae-125668	Triticum aestivum	50.00	5.00e-95	342.00
IUUC-Tur-126181	Triticum urartu	47.83	3.00e-87	316.00
IUUC-Tbe-127518	Tupaia belangeri	65.71	2.00e-150	525.00
IUUC-Ttr-128172	Tursiops truncatus	78.96	0.00e+00	936.00
IUUC-Vvi-131489	Vitis vinifera	52.54	6.00e-96	345.00
IUUC-Xtr-132915	Xenopus tropicalis	71.30	0.00e+00	909.00
IUUC-Xma-134133	Xiphophorus maculatus	59.15	0.00e+00	759.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence