iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040525

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000184

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000005292.6	ENSGALT00000008484.6	ENSGALP00000008470.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.40e-26	90.5	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.20e-08	33.3	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+v+g+ef++h++vLaa+S++F+a+fl+++eesk k +v ++dv+p+v+  +l+++Yt++l+++e
   Q: 34   DCVLKVKGKEFPCHRLVLAACSPYFRAMFLSDMEESK-KREVSLEDVDPDVMGKILHYIYTSELEITE 100
           9************************************.*************************99865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Ncl+i+r++ ++dc +L+ aa+dfi++ F
   Q: 132  LSNCLAIFRLGLMLDCARLAVAARDFICDRF 162
           69***************************99 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MGLPFDQVEE LRLYQQTLLQ DGLKDMLDHN KFLDCVLKVK GKEFPCHRLV LAACSPYFRA 60
MFLSDMEESK KREVSLEDVD PDVMGKILHY IYTSELEITE QNVQDIFSVA NMFQIPSIFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTTTGC CTTTTGATCA AGTGGAAGAA CTGCGTCTCT ACCAGCAAAC CCTCCTCCAG 60
GATGGACTCA AAGACATGTT GGACCACAAT AAGTTTCTGG ACTGTGTCTT GAAAGTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031672--C:A band
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031674--C:I band
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016567--P:protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	68.05	0.00e+00	840.00
IUUC-Apl-003748	Anas platyrhynchos	97.42	0.00e+00	1153.00
IUUC-Aca-005275	Anolis carolinensis	79.33	0.00e+00	969.00
IUUC-Ath-007591	Arabidopsis thaliana	30.58	1.00e-13	71.20
IUUC-Ame-011294	Astyanax mexicanus	64.52	0.00e+00	798.00
IUUC-Bta-012801	Bos taurus	70.77	0.00e+00	907.00
IUUC-Bdi-014457	Brachypodium distachyon	25.11	2.00e-11	63.90
IUUC-Cja-019795	Callithrix jacchus	70.65	0.00e+00	820.00
IUUC-Cpo-022436	Cavia porcellus	69.45	0.00e+00	905.00
IUUC-Cre-022652	Chlamydomonas reinhardtii	33.33	9.00e-11	60.50
IUUC-Csa-023105	Chlorocebus sabaeus	71.43	0.00e+00	915.00
IUUC-Dre-028603	Danio rerio	64.40	0.00e+00	816.00
IUUC-Eca-034393	Equus caballus	70.69	0.00e+00	846.00
IUUC-Fca-035823	Felis catus	62.46	0.00e+00	765.00
IUUC-Fal-037632	Ficedula albicollis	95.15	0.00e+00	1118.00
IUUC-Gmo-039697	Gadus morhua	61.51	0.00e+00	776.00
IUUC-Gac-042421	Gasterosteus aculeatus	66.13	0.00e+00	832.00
IUUC-Gma-043151	Glycine max	29.44	7.00e-15	75.50
IUUC-Ggo-045596	Gorilla gorilla	71.43	0.00e+00	910.00
IUUC-Hsa-046235	Homo sapiens	71.27	0.00e+00	905.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	71.93	0.00e+00	922.00
IUUC-Lch-050123	Latimeria chalumnae	71.31	0.00e+00	913.00
IUUC-Loc-051824	Lepisosteus oculatus	70.11	0.00e+00	881.00
IUUC-Mcc-054909	Macaca mulatta	71.43	0.00e+00	913.00
IUUC-Meu-055972	Macropus eugenii	71.79	0.00e+00	911.00
IUUC-Mga-059451	Meleagris gallopavo	99.03	0.00e+00	1191.00
IUUC-Mmr-060736	Microcebus murinus	71.06	0.00e+00	911.00
IUUC-Mdo-062563	Monodelphis domestica	72.52	0.00e+00	728.00
IUUC-Mmu-063549	Mus musculus	71.47	0.00e+00	910.00
IUUC-Mpu-066262	Mustela putorius furo	72.36	0.00e+00	924.00
IUUC-Mlu-067210	Myotis lucifugus	71.84	0.00e+00	913.00
IUUC-Opr-070384	Ochotona princeps	67.52	0.00e+00	838.00
IUUC-Ont-071273	Oreochromis niloticus	66.29	0.00e+00	832.00
IUUC-Ocu-074499	Oryctolagus cuniculus	71.38	0.00e+00	913.00
IUUC-Ola-087175	Oryzias latipes	64.41	0.00e+00	800.00
IUUC-Oga-088855	Otolemur garnettii	71.22	0.00e+00	911.00
IUUC-Oar-089342	Ovis aries	61.73	0.00e+00	699.00
IUUC-Ptr-091028	Pan troglodytes	67.65	4.00e-177	613.00
IUUC-Pan-091827	Papio anubis	71.59	0.00e+00	915.00
IUUC-Psi-092998	Pelodiscus sinensis	88.85	0.00e+00	1066.00
IUUC-Pma-094586	Petromyzon marinus	62.63	2.00e-101	361.00
IUUC-Pfo-096216	Poecilia formosa	64.03	0.00e+00	822.00
IUUC-Pva-102331	Pteropus vampyrus	64.54	0.00e+00	814.00
IUUC-Pgr-103484	Puccinia graminis	25.34	2.00e-04	42.00
IUUC-Pte-104106	Pyrenophora teres	29.56	9.00e-11	60.50
IUUC-Rno-105613	Rattus norvegicus	69.95	0.00e+00	790.00
IUUC-Sha-107091	Sarcophilus harrisii	73.23	0.00e+00	954.00
IUUC-Ssc-116276	Sus scrofa	70.77	0.00e+00	909.00
IUUC-Tgu-116494	Taeniopygia guttata	95.48	0.00e+00	1151.00
IUUC-Tru-118614	Takifugu rubripes	65.81	0.00e+00	835.00
IUUC-Tni-119776	Tetraodon nigroviridis	65.16	0.00e+00	829.00
IUUC-Tbe-127806	Tupaia belangeri	65.87	0.00e+00	836.00
IUUC-Ttr-128813	Tursiops truncatus	70.72	0.00e+00	898.00
IUUC-Xtr-132942	Xenopus tropicalis	76.58	0.00e+00	954.00
IUUC-Xma-133573	Xiphophorus maculatus	63.99	0.00e+00	809.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence