iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066282

Ensembl Protein ID

ENSMPUP00000002007.1

UniProt Accession

M3XSF7; M3XSF7_MUSPF

Genbank Protein ID

ENSMPUP00000002007

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01082588

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000002028.1	ENSMPUT00000002050.1	ENSMPUP00000002007.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.40e-10	39.4	548	585
ULD/UDP/UBQ/UBQ_PIM	4.50e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 548  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 585
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAESGESGGP PSSQDSAAAA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGA GTGGTGAAAG CGGCGGCCCT CCGAGCTCCC AGGACAGCGC CGCCGCGGCC 60
GAAGGTGCCG GCGCCCCCGC GGCCGCTGCC TCGGCTGAGC CCAAGATCAT GAAAGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	7.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	93.31	0.00e+00	795.00
IUUC-Atr-002470	Amborella trichopoda	40.66	6.00e-44	172.00
IUUC-Apl-003241	Anas platyrhynchos	80.07	0.00e+00	706.00
IUUC-Aca-004511	Anolis carolinensis	78.83	0.00e+00	709.00
IUUC-Aly-005419	Arabidopsis lyrata	36.99	1.00e-51	197.00
IUUC-Ath-007271	Arabidopsis thaliana	35.00	5.00e-50	192.00
IUUC-Ago-007963	Ashbya gossypii	37.68	9.00e-09	54.30
IUUC-Ani-009418	Aspergillus nidulans	25.58	1.00e-08	54.70
IUUC-Bta-013048	Bos taurus	92.35	0.00e+00	814.00
IUUC-Bra-018014	Brassica rapa	37.71	3.00e-41	162.00
IUUC-Cel-018631	Caenorhabditis elegans	40.52	1.00e-59	224.00
IUUC-Cja-019976	Callithrix jacchus	92.63	0.00e+00	803.00
IUUC-Cfa-020092	Canis familiaris	94.42	0.00e+00	809.00
IUUC-Cpo-022388	Cavia porcellus	93.53	0.00e+00	788.00
IUUC-Csa-024087	Chlorocebus sabaeus	92.36	0.00e+00	805.00
IUUC-Cho-024834	Choloepus hoffmanni	92.34	0.00e+00	815.00
IUUC-Cin-025136	Ciona intestinalis	50.46	1.00e-111	397.00
IUUC-Csv-026009	Ciona savignyi	53.22	1.00e-101	363.00
IUUC-Cme-027155	Cyanidioschyzon merolae	57.55	1.00e-34	140.00
IUUC-Dno-028970	Dasypus novemcinctus	75.66	0.00e+00	637.00
IUUC-Dor-030519	Dipodomys ordii	92.81	0.00e+00	775.00
IUUC-Dse-031421	Dothistroma septosporum	27.49	9.00e-13	68.20
IUUC-Dme-032013	Drosophila melanogaster	48.71	8.00e-96	344.00
IUUC-Ete-032273	Echinops telfairi	90.38	0.00e+00	779.00
IUUC-Eca-033667	Equus caballus	91.69	0.00e+00	805.00
IUUC-Eeu-034865	Erinaceus europaeus	71.26	1.00e-157	550.00
IUUC-Fca-036179	Felis catus	91.20	0.00e+00	775.00
IUUC-Fal-037642	Ficedula albicollis	82.68	0.00e+00	741.00
IUUC-Gga-041264	Gallus gallus	82.29	0.00e+00	787.00
IUUC-Gma-044112	Glycine max	50.32	9.00e-40	157.00
IUUC-Ggo-044969	Gorilla gorilla	92.45	0.00e+00	783.00
IUUC-Hsa-046669	Homo sapiens	92.63	0.00e+00	816.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	93.44	0.00e+00	677.00
IUUC-Lch-050192	Latimeria chalumnae	76.52	0.00e+00	661.00
IUUC-Lpe-051401	Leersia perrieri	38.67	3.00e-36	146.00
IUUC-Loc-052846	Lepisosteus oculatus	78.35	0.00e+00	672.00
IUUC-Lma-053152	Leptosphaeria maculans	30.55	2.00e-12	67.00
IUUC-Laf-054278	Loxodonta africana	93.73	0.00e+00	767.00
IUUC-Mcc-055680	Macaca mulatta	92.81	0.00e+00	816.00
IUUC-Meu-056207	Macropus eugenii	71.96	4.00e-167	581.00
IUUC-Mtr-058674	Medicago truncatula	37.46	4.00e-39	155.00
IUUC-Mga-059894	Meleagris gallopavo	83.09	0.00e+00	632.00
IUUC-Mmr-061094	Microcebus murinus	92.45	0.00e+00	790.00
IUUC-Mdo-062728	Monodelphis domestica	81.34	0.00e+00	754.00
IUUC-Mmu-064088	Mus musculus	85.16	0.00e+00	816.00
IUUC-Mac-065526	Musa acuminata	33.01	2.00e-46	180.00
IUUC-Mlu-068158	Myotis lucifugus	93.71	0.00e+00	764.00
IUUC-Nle-069321	Nomascus leucogenys	92.45	0.00e+00	816.00
IUUC-Opr-071098	Ochotona princeps	84.98	2.00e-178	618.00
IUUC-Oan-072808	Ornithorhynchus anatinus	83.33	0.00e+00	722.00
IUUC-Ocu-074301	Oryctolagus cuniculus	87.43	0.00e+00	759.00
IUUC-Oba-074973	Oryza barthii	39.33	1.00e-42	167.00
IUUC-Obr-076444	Oryza brachyantha	50.34	2.00e-32	134.00
IUUC-Ogl-077319	Oryza glaberrima	34.38	7.00e-45	175.00
IUUC-Ogu-078074	Oryza glumaepatula	34.38	5.00e-45	175.00
IUUC-Oin-079142	Oryza indica	34.27	2.00e-44	173.00
IUUC-Olo-080565	Oryza longistaminata	34.22	2.00e-44	173.00
IUUC-Ome-081155	Oryza meridionalis	51.55	4.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	34.27	2.00e-44	173.00
IUUC-Opu-083241	Oryza punctata	34.62	2.00e-45	176.00
IUUC-Oru-085257	Oryza rufipogon	34.27	2.00e-44	173.00
IUUC-Osa-086257	Oryza sativa	34.38	6.00e-45	175.00
IUUC-Ola-086802	Oryzias latipes	67.80	5.00e-138	484.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.12	5.00e-25	108.00
IUUC-Oga-088495	Otolemur garnettii	91.73	0.00e+00	797.00
IUUC-Oar-089711	Ovis aries	91.69	0.00e+00	785.00
IUUC-Ptr-091439	Pan troglodytes	92.27	0.00e+00	811.00
IUUC-Pan-092641	Papio anubis	92.81	0.00e+00	816.00
IUUC-Psi-093518	Pelodiscus sinensis	80.37	0.00e+00	691.00
IUUC-Pma-094727	Petromyzon marinus	42.26	6.00e-51	195.00
IUUC-Ppa-095702	Physcomitrella patens	37.58	5.00e-42	165.00
IUUC-Pfo-096638	Poecilia formosa	67.27	1.00e-171	596.00
IUUC-Pab-098699	Pongo abelii	90.29	0.00e+00	808.00
IUUC-Pop-099549	Populus trichocarpa	36.05	1.00e-51	197.00
IUUC-Pca-100497	Procavia capensis	82.72	1.00e-125	443.00
IUUC-Pva-102513	Pteropus vampyrus	85.02	5.00e-150	524.00
IUUC-Rno-104908	Rattus norvegicus	85.07	0.00e+00	842.00
IUUC-Sce-106332	Saccharomyces cerevisiae	34.09	5.00e-17	82.00
IUUC-Sha-106881	Sarcophilus harrisii	81.94	0.00e+00	677.00
IUUC-Spo-108223	Schizosaccharomyces pombe	29.03	2.00e-12	66.20
IUUC-Sit-110766	Setaria italica	39.74	5.00e-36	145.00
IUUC-Sly-111731	Solanum lycopersicum	39.44	2.00e-41	163.00
IUUC-Stu-112263	Solanum tuberosum	36.86	1.00e-37	150.00
IUUC-Sar-113648	Sorex araneus	84.79	5.00e-174	603.00
IUUC-Sbi-114307	Sorghum bicolor	38.46	8.00e-45	174.00
IUUC-Sre-115081	Sporisorium reilianum	25.30	7.00e-12	64.70
IUUC-Ssc-115820	Sus scrofa	93.53	0.00e+00	808.00
IUUC-Tgu-116845	Taeniopygia guttata	78.42	0.00e+00	666.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.54	4.00e-167	581.00
IUUC-Tca-121558	Theobroma cacao	34.09	2.00e-52	200.00
IUUC-Tae-125518	Triticum aestivum	49.65	2.00e-38	153.00
IUUC-Tur-126248	Triticum urartu	49.65	3.00e-38	153.00
IUUC-Tme-127116	Tuber melanosporum	25.91	2.00e-09	57.00
IUUC-Tbe-127379	Tupaia belangeri	82.67	0.00e+00	667.00
IUUC-Ttr-128630	Tursiops truncatus	94.27	0.00e+00	815.00
IUUC-Uma-129639	Ustilago maydis	26.19	2.00e-11	63.90
IUUC-Vpa-130413	Vicugna pacos	77.92	1.00e-139	489.00
IUUC-Vvi-131599	Vitis vinifera	39.86	5.00e-42	165.00
IUUC-Xtr-132595	Xenopus tropicalis	79.01	0.00e+00	681.00
IUUC-Xma-134155	Xiphophorus maculatus	62.07	3.00e-169	588.00
IUUC-Zma-135715	Zea mays	38.46	4.00e-41	162.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence