iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118278

Ensembl Protein ID

ENSTRUP00000036975.1

UniProt Accession

H2UJ54; H2UJ54_TAKRU

Protein Name

Uncharacterized protein

Gene Name

arhgef7a; LOC101064301

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000014456.1	ENSTRUT00000037102.1	ENSTRUP00000036970.1
ENSTRUG00000014456.1	ENSTRUT00000037103.1	ENSTRUP00000036971.1
ENSTRUG00000014456.1	ENSTRUT00000037104.1	ENSTRUP00000036972.1
ENSTRUG00000014456.1	ENSTRUT00000037105.1	ENSTRUP00000036973.1
ENSTRUG00000014456.1	ENSTRUT00000037106.1	ENSTRUP00000036974.1
ENSTRUG00000014456.1	ENSTRUT00000037107.1	ENSTRUP00000036975.1
ENSTRUG00000014456.1	ENSTRUT00000037108.1	ENSTRUP00000036976.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.00e-16	59.6	114	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +v++ ++++ +n+deLt++kGd++ v    ++++gW++g  +l+g+ G fP+n+v++++
   Q: 114  LLVKARFNFQQTNEDELTFTKGDIISVS--RQEEGGWWEG--TLNGRTGWFPSNYVREVK 169
           5799***********************7..9999******..8**************996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

FLQIYQEPKN DGECLYNIKE FLKGCTSFRV EPFEASDLLL GLNFSKVLSS LVALNKVTAD 60
ISVGSDSVSA RHSSSHRIKS FESLSCQTSL GRSSKLLQNQ FRSLDMSENS GQQLLVKARF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATTCGG CGGAACAGAC GGTTACATGG TTGATCACGC TCGGGGTGCT GGAATCGCCG 60
AAGAAGACCA TCTCGGATCC TGAAGCGTTT CTCCAGAGTT CCTTGAAAGA TGGGGTGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	70.50	0.00e+00	946.00
IUUC-Aca-004591	Anolis carolinensis	72.01	0.00e+00	1018.00
IUUC-Ame-010759	Astyanax mexicanus	80.07	0.00e+00	1262.00
IUUC-Bta-013328	Bos taurus	71.76	0.00e+00	1083.00
IUUC-Bci-013864	Botrytis cinerea	45.61	5.00e-12	67.40
IUUC-Cja-018742	Callithrix jacchus	73.52	0.00e+00	938.00
IUUC-Cfa-020756	Canis familiaris	65.73	0.00e+00	942.00
IUUC-Cpo-021284	Cavia porcellus	71.76	0.00e+00	1056.00
IUUC-Csa-023162	Chlorocebus sabaeus	73.37	0.00e+00	1091.00
IUUC-Cho-024736	Choloepus hoffmanni	60.29	1.00e-136	480.00
IUUC-Cin-025535	Ciona intestinalis	40.24	4.00e-91	328.00
IUUC-Cne-026866	Cryptococcus neoformans	54.90	4.00e-13	70.90
IUUC-Dre-028646	Danio rerio	78.49	0.00e+00	1225.00
IUUC-Dno-029461	Dasypus novemcinctus	71.89	0.00e+00	1080.00
IUUC-Dor-030623	Dipodomys ordii	63.51	0.00e+00	803.00
IUUC-Dme-032219	Drosophila melanogaster	44.87	3.00e-101	363.00
IUUC-Ete-032236	Echinops telfairi	61.51	5.00e-176	611.00
IUUC-Eca-034137	Equus caballus	72.31	0.00e+00	1040.00
IUUC-Fca-035742	Felis catus	66.54	0.00e+00	918.00
IUUC-Fal-037205	Ficedula albicollis	72.98	0.00e+00	957.00
IUUC-Gmo-039475	Gadus morhua	77.26	0.00e+00	1127.00
IUUC-Gga-040539	Gallus gallus	66.34	0.00e+00	859.00
IUUC-Gac-042615	Gasterosteus aculeatus	78.77	0.00e+00	1073.00
IUUC-Ggo-044470	Gorilla gorilla	70.82	0.00e+00	1018.00
IUUC-Hsa-046398	Homo sapiens	72.20	0.00e+00	956.00
IUUC-Loc-052146	Lepisosteus oculatus	78.02	0.00e+00	1168.00
IUUC-Laf-053891	Loxodonta africana	72.35	0.00e+00	1078.00
IUUC-Mcc-055483	Macaca mulatta	71.79	0.00e+00	955.00
IUUC-Mga-059410	Meleagris gallopavo	71.50	0.00e+00	1052.00
IUUC-Mmr-060758	Microcebus murinus	72.36	0.00e+00	909.00
IUUC-Mdo-061900	Monodelphis domestica	65.23	0.00e+00	971.00
IUUC-Mmu-063849	Mus musculus	72.22	0.00e+00	930.00
IUUC-Mpu-065876	Mustela putorius furo	73.27	0.00e+00	881.00
IUUC-Mlu-067970	Myotis lucifugus	72.82	0.00e+00	1050.00
IUUC-Nle-069685	Nomascus leucogenys	65.06	0.00e+00	894.00
IUUC-Opr-071132	Ochotona princeps	51.38	9.00e-164	570.00
IUUC-Ont-071815	Oreochromis niloticus	91.10	0.00e+00	1409.00
IUUC-Oan-073057	Ornithorhynchus anatinus	73.13	0.00e+00	963.00
IUUC-Ola-086663	Oryzias latipes	90.12	0.00e+00	1338.00
IUUC-Oga-088103	Otolemur garnettii	72.30	0.00e+00	1005.00
IUUC-Ptr-091162	Pan troglodytes	71.26	0.00e+00	957.00
IUUC-Pan-092093	Papio anubis	66.63	0.00e+00	998.00
IUUC-Pma-094261	Petromyzon marinus	62.46	2.00e-119	421.00
IUUC-Pfo-096736	Poecilia formosa	83.93	0.00e+00	1251.00
IUUC-Pab-097641	Pongo abelii	66.21	0.00e+00	982.00
IUUC-Pva-102819	Pteropus vampyrus	69.17	0.00e+00	893.00
IUUC-Pte-104123	Pyrenophora teres	46.43	3.00e-11	64.30
IUUC-Pyt-104567	Pyrenophora triticirepentis	46.43	3.00e-11	64.30
IUUC-Rno-106099	Rattus norvegicus	71.27	0.00e+00	1041.00
IUUC-Sha-106845	Sarcophilus harrisii	65.13	0.00e+00	935.00
IUUC-Ssl-108538	Sclerotinia sclerotiorum	43.86	3.00e-11	64.70
IUUC-Ssc-116036	Sus scrofa	65.61	0.00e+00	930.00
IUUC-Tgu-117498	Taeniopygia guttata	72.20	0.00e+00	1092.00
IUUC-Tsy-118990	Tarsius syrichta	72.91	0.00e+00	753.00
IUUC-Tni-120852	Tetraodon nigroviridis	85.45	0.00e+00	1279.00
IUUC-Ttr-128922	Tursiops truncatus	67.89	0.00e+00	883.00
IUUC-Vpa-130144	Vicugna pacos	49.02	3.00e-157	548.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence