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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064257
UUCD1 version UUC-MuM-00281
Ensembl Protein ID ENSMUSP00000112801.1
UniProt Accession G5E8T2; G5E8T2_MOUSE
Genbank Protein ID EDL03730.1
Protein Name E3 ubiquitin-protein ligase TTC3; Tetratricopeptide repeat domain 3, isoform CRA_b
Genbank Nucleotide ID AC173208
Gene Name Ttc3; mCG_19601
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000040785.18 ENSMUST00000117648.7 ENSMUSP00000112801.1
ENSMUSG00000040785.18 ENSMUST00000147352.7 ENSMUSP00000116097.1
ENSMUSG00000040785.18 ENSMUST00000155692.7 ENSMUSP00000122724.1
ENSMUSG00000040785.18 ENSMUST00000139513.7 ENSMUSP00000117881.1
ENSMUSG00000040785.18 ENSMUST00000154243.7 ENSMUSP00000122439.1
ENSMUSG00000040785.18 ENSMUST00000122895.7 ENSMUSP00000123037.1
ENSMUSG00000040785.18 ENSMUST00000151770.7 ENSMUSP00000121349.1
ENSMUSG00000040785.18 ENSMUST00000127667.7 ENSMUSP00000122425.1
ENSMUSG00000040785.18 ENSMUST00000119131.1 ENSMUSP00000113311.1
ENSMUSG00000040785.18 ENSMUST00000141176.1 ENSMUSP00000114483.1
ENSMUSG00000040785.18 ENSMUST00000141192.7 ENSMUSP00000117530.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLMPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.00e-07 33.5 1931 1970
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C iC+e f  k+  +vl CgH fh+ C+++w       +++ +CP+C
   Q: 1931 CEICHEIFksKN-MRVLKCGHKFHKGCFKQW------LKGQSTCPTC 1970
           99****998555.******************......********** PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK 60
NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064257|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGGCTGGCA GGCGCCCCCG CCGCTTGGCG CAGGCGCACC GCGACCGCAG CGAGGGGGCT 60
AGCACGGTCT CACCACCCAC CCCACCGAGC TGAGGGGGCG ACGCGGCGAC TGCGCATGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064257|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
Interpro

IPR011029--DEATH-like_dom
IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
SM00028--TPR
Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG mmu:22129
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002231 Ailuropoda melanoleuca 88.89 5.00e-27 112.00
IUUC-Apl-003622 Anas platyrhynchos 47.79 0.00e+00 1013.00
IUUC-Aca-004579 Anolis carolinensis 35.70 8.00e-64 238.00
IUUC-Ame-011167 Astyanax mexicanus 32.84 0.00e+00 790.00
IUUC-Bta-012916 Bos taurus 71.74 0.00e+00 2636.00
IUUC-Cja-019100 Callithrix jacchus 75.76 0.00e+00 2697.00
IUUC-Cfa-020974 Canis familiaris 75.42 0.00e+00 2818.00
IUUC-Cpo-022435 Cavia porcellus 63.52 0.00e+00 1763.00
IUUC-Csa-023245 Chlorocebus sabaeus 75.64 0.00e+00 2805.00
IUUC-Cho-024822 Choloepus hoffmanni 62.18 0.00e+00 1244.00
IUUC-Cme-027114 Cyanidioschyzon merolae 38.33 6.00e-07 48.50
IUUC-Dre-027805 Danio rerio 36.50 4.00e-107 384.00
IUUC-Dno-029413 Dasypus novemcinctus 61.18 0.00e+00 2186.00
IUUC-Dor-030670 Dipodomys ordii 78.95 0.00e+00 1482.00
IUUC-Ete-032367 Echinops telfairi 40.93 2.00e-79 292.00
IUUC-Eca-033891 Equus caballus 74.76 0.00e+00 2779.00
IUUC-Fca-035889 Felis catus 74.94 0.00e+00 2756.00
IUUC-Fal-037399 Ficedula albicollis 43.41 0.00e+00 887.00
IUUC-Gga-040490 Gallus gallus 45.83 0.00e+00 940.00
IUUC-Ggo-045441 Gorilla gorilla 72.24 0.00e+00 2622.00
IUUC-Hsa-045811 Homo sapiens 75.86 0.00e+00 2815.00
IUUC-Itr-048367 Ictidomys tridecemlineatus 71.69 0.00e+00 763.00
IUUC-Lch-049809 Latimeria chalumnae 42.46 1.00e-130 461.00
IUUC-Loc-052533 Lepisosteus oculatus 37.28 0.00e+00 702.00
IUUC-Laf-053785 Loxodonta africana 65.29 0.00e+00 1510.00
IUUC-Mcc-054801 Macaca mulatta 76.09 0.00e+00 2823.00
IUUC-Mga-059963 Meleagris gallopavo 42.07 0.00e+00 1020.00
IUUC-Mmr-060707 Microcebus murinus 74.81 0.00e+00 2698.00
IUUC-Mdo-062718 Monodelphis domestica 47.38 0.00e+00 1163.00
IUUC-Mpu-066020 Mustela putorius furo 74.86 0.00e+00 2787.00
IUUC-Mlu-067023 Myotis lucifugus 70.81 0.00e+00 2598.00
IUUC-Nle-069999 Nomascus leucogenys 76.79 0.00e+00 2878.00
IUUC-Opr-070629 Ochotona princeps 61.35 0.00e+00 926.00
IUUC-Ont-072604 Oreochromis niloticus 34.69 6.00e-153 536.00
IUUC-Oan-072830 Ornithorhynchus anatinus 46.01 0.00e+00 1410.00
IUUC-Ocu-073774 Oryctolagus cuniculus 75.40 0.00e+00 2762.00
IUUC-Ola-086847 Oryzias latipes 35.96 4.00e-150 525.00
IUUC-Oga-088372 Otolemur garnettii 73.96 0.00e+00 2031.00
IUUC-Oar-090039 Ovis aries 70.55 0.00e+00 2612.00
IUUC-Ptr-091171 Pan troglodytes 75.76 0.00e+00 2804.00
IUUC-Pan-091926 Papio anubis 73.34 0.00e+00 2810.00
IUUC-Psi-093680 Pelodiscus sinensis 48.25 0.00e+00 1038.00
IUUC-Pab-098120 Pongo abelii 76.71 0.00e+00 2863.00
IUUC-Pva-102424 Pteropus vampyrus 66.18 0.00e+00 1371.00
IUUC-Rno-105101 Rattus norvegicus 92.88 0.00e+00 3444.00
IUUC-Sha-106607 Sarcophilus harrisii 60.94 0.00e+00 886.00
IUUC-Sar-113589 Sorex araneus 69.41 0.00e+00 2005.00
IUUC-Ssc-115530 Sus scrofa 78.29 0.00e+00 2283.00
IUUC-Tgu-116671 Taeniopygia guttata 42.84 0.00e+00 764.00
IUUC-Tru-118283 Takifugu rubripes 35.13 1.00e-142 500.00
IUUC-Tsy-118872 Tarsius syrichta 68.11 0.00e+00 1804.00
IUUC-Tbe-127996 Tupaia belangeri 66.39 0.00e+00 1494.00
IUUC-Ttr-128379 Tursiops truncatus 73.57 0.00e+00 2625.00
IUUC-Vpa-130372 Vicugna pacos 71.22 0.00e+00 2192.00
IUUC-Xtr-132649 Xenopus tropicalis 34.62 0.00e+00 949.00
Created Date 25-Jun-2017

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