iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011759

Ensembl Protein ID

ENSAMXP00000002025.1

UniProt Accession

W5K364; W5K364_ASTMX

Genbank Protein ID

ENSAMXP00000002025

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01119524

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000001969.1	ENSAMXT00000002025.1	ENSAMXP00000002025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-50	168.8	1098	1150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+++de+++ kG  + v   ++ d +W+kg  el+g  GlfP n+++ 
   Q: 1098 QVIAMYDYKAASEDEMSFLKGQLINVF--NKDDSDWWKG--ELNGVTGLFPTNYIKM 1150
           689***********************9..78899*****..9*************85 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

GGFNIWAITP EERGKHDKQF DSLTPTLGYV SGDQARKFFL QSGLPSSVLA EIWALADMGR 60
DGKMDRLEFS IAMKLIKLQL QGQPLPSSLP SIMKQTPVPV MPSAAHFGMG SMPNLSVMPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGATTTA ATATTTGGGC TATAACTCCA GAGGAGAGAG GAAAACATGA TAAACAGTTT 60
GACTCTCTTA CTCCTACACT GGGATACGTG TCAGGTGAGT GTACACACAC ACACACACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR020838--DBINO
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS51413--DBINO
PS00741--DH_1
PS50010--DH_2
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0003677--F:DNA binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	31.85	1.00e-10	62.80
IUUC-Aml-001455	Ailuropoda melanoleuca	65.42	0.00e+00	1242.00
IUUC-Aca-004287	Anolis carolinensis	64.75	0.00e+00	1266.00
IUUC-Bta-013248	Bos taurus	64.50	0.00e+00	1223.00
IUUC-Cel-018490	Caenorhabditis elegans	28.94	2.00e-45	178.00
IUUC-Cfa-020628	Canis familiaris	64.72	0.00e+00	1240.00
IUUC-Csa-023122	Chlorocebus sabaeus	65.50	0.00e+00	1249.00
IUUC-Cne-026918	Cryptococcus neoformans	37.70	7.00e-42	167.00
IUUC-Cme-027247	Cyanidioschyzon merolae	24.73	6.00e-13	69.30
IUUC-Dre-027849	Danio rerio	80.33	0.00e+00	1501.00
IUUC-Dno-029419	Dasypus novemcinctus	64.89	0.00e+00	1232.00
IUUC-Dme-032099	Drosophila melanogaster	32.62	2.00e-53	205.00
IUUC-Eca-034196	Equus caballus	63.29	0.00e+00	1185.00
IUUC-Fca-035757	Felis catus	65.07	0.00e+00	1245.00
IUUC-Gmo-039555	Gadus morhua	72.73	0.00e+00	1176.00
IUUC-Gac-041320	Gasterosteus aculeatus	71.62	0.00e+00	1174.00
IUUC-Ggo-045405	Gorilla gorilla	65.71	0.00e+00	1246.00
IUUC-Hsa-046833	Homo sapiens	65.81	0.00e+00	1251.00
IUUC-Lch-050094	Latimeria chalumnae	65.88	0.00e+00	1288.00
IUUC-Loc-052646	Lepisosteus oculatus	68.47	0.00e+00	1347.00
IUUC-Mcc-054709	Macaca mulatta	65.50	0.00e+00	1249.00
IUUC-Mga-059997	Meleagris gallopavo	56.60	0.00e+00	1373.00
IUUC-Mvi-060268	Microbotryum violaceum	32.53	8.00e-48	186.00
IUUC-Mmu-064226	Mus musculus	64.11	0.00e+00	1251.00
IUUC-Mpu-066431	Mustela putorius furo	64.89	0.00e+00	1241.00
IUUC-Mlu-068190	Myotis lucifugus	64.93	0.00e+00	1251.00
IUUC-Nle-070116	Nomascus leucogenys	60.00	0.00e+00	876.00
IUUC-Ont-072464	Oreochromis niloticus	68.83	0.00e+00	1295.00
IUUC-Ola-087489	Oryzias latipes	66.86	0.00e+00	1152.00
IUUC-Olu-087698	Ostreococcus lucimarinus	28.21	3.00e-17	84.00
IUUC-Oga-088449	Otolemur garnettii	64.67	0.00e+00	1241.00
IUUC-Oar-090275	Ovis aries	64.93	0.00e+00	1239.00
IUUC-Ptr-091667	Pan troglodytes	65.50	0.00e+00	1244.00
IUUC-Pfo-096864	Poecilia formosa	65.27	0.00e+00	1234.00
IUUC-Pab-098755	Pongo abelii	62.94	0.00e+00	1181.00
IUUC-Rno-105691	Rattus norvegicus	64.99	0.00e+00	1264.00
IUUC-Smo-108995	Selaginella moellendorffii	28.95	2.00e-07	50.40
IUUC-Stu-112258	Solanum tuberosum	36.36	1.00e-08	54.70
IUUC-Sar-112978	Sorex araneus	56.68	0.00e+00	634.00
IUUC-Ssc-115562	Sus scrofa	59.74	0.00e+00	1108.00
IUUC-Tru-117714	Takifugu rubripes	65.76	0.00e+00	1211.00
IUUC-Tni-119958	Tetraodon nigroviridis	68.54	0.00e+00	1281.00
IUUC-Ttr-129196	Tursiops truncatus	63.21	0.00e+00	1191.00
IUUC-Uma-129456	Ustilago maydis	32.68	3.00e-33	138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence