iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pca-100275

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Recombination activating protein 1

Genbank Nucleotide ID

AY239192

Gene Name

RAG-1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPCAG00000013367.1	ENSPCAT00000013338.1	ENSPCAP00000012463.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-06	27.3	11	52
E3 activity/RING/U-box	6.70e-06	25.8	7	71

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ + d p++  CgH f++ Cl   w     ++   +rCP+Cr
   Q: 11   CLICLNYLTD-PVTICCGHNFCRACLcLSW----EKAESPARCPICR 52
           **********.999****************....77999999****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl....asggk..tcPvtrqplteedlvPnltlrrliq 66
           +e++C I l+  +dPv++++G+ + r+++  +l    a+  +   cP++r++ ++++++ n  +++l++
   Q: 7    KELNCLICLNYLTDPVTICCGHNFCRACL--CLswekAE--SpaRCPICRETSEQTEFKTNVLIKNLVS 71
           6899************************9..66332333..3569********************9986 PP

Organism

Procavia capensis

Protein Sequence
(Fasta)

MASVFEKELN CLICLNYLTD PVTICCGHNF CRACLCLSWE KAESPARCPI CRETSEQTEF 60
KTNVLIKNLV SLARQASLRQ FLSSEEQMCE AHKETKKMFC EENKSLLCLL CSSSEEHEAH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCAG TCTTTGAGAA GGAACTCAAC TGCTTAATCT GCTTGAACTA CCTAACAGAC 60
CCTGTCACCA TATGCTGTGG ACACAACTTC TGTAGGGCCT GTCTCTGCCT TTCCTGGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012834	Bos taurus	39.64	5.00e-84	304.00
IUUC-Cja-019010	Callithrix jacchus	52.34	8.00e-125	440.00
IUUC-Csa-024131	Chlorocebus sabaeus	58.09	8.00e-148	516.00
IUUC-Cho-024585	Choloepus hoffmanni	60.59	6.00e-156	543.00
IUUC-Dno-029845	Dasypus novemcinctus	59.91	2.00e-147	515.00
IUUC-Eca-033627	Equus caballus	56.63	6.00e-142	496.00
IUUC-Gma-042739	Glycine max	40.68	1.00e-08	53.50
IUUC-Hsa-046700	Homo sapiens	58.65	2.00e-146	511.00
IUUC-Laf-053917	Loxodonta africana	73.26	0.00e+00	631.00
IUUC-Mcc-054788	Macaca mulatta	57.30	4.00e-142	497.00
IUUC-Mtr-057657	Medicago truncatula	42.37	5.00e-09	55.10
IUUC-Mmr-061646	Microcebus murinus	50.11	3.00e-114	404.00
IUUC-Nle-069150	Nomascus leucogenys	56.63	2.00e-134	471.00
IUUC-Opr-070996	Ochotona princeps	43.67	1.00e-92	333.00
IUUC-Ocu-074806	Oryctolagus cuniculus	53.76	1.00e-127	449.00
IUUC-Oga-088482	Otolemur garnettii	56.56	1.00e-135	476.00
IUUC-Oar-090163	Ovis aries	45.37	2.00e-98	352.00
IUUC-Ptr-090899	Pan troglodytes	59.10	1.00e-147	515.00
IUUC-Pab-098214	Pongo abelii	59.10	5.00e-148	516.00
IUUC-Ssc-115481	Sus scrofa	51.00	5.00e-119	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence