iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001594

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01128797

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017567.1	ENSAMET00000019313.1	ENSAMEP00000018568.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.70e-08	32.7	12	53
UBD/SH3	2.80e-30	104.2	386	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRI----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l+kG+ ++v+   +   gWl+gv+  +g+ G+fP+n+v 
   Q: 386  NMFVALHSYSAHGPDELDLQKGEGIRVL--GKYPDGWLRGVSLVTGRVGIFPNNYVI 440
           7889************************..77788********************96 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRI FKAHKELRCP ECRTLVFCSI 60
EALPANLLLV RLLDGVRSGQ SSGRGGSFRR PGVLTPQDSR KSRTNPRGLQ SSPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGACGTTACT TGATCTTCTG GAGTGCCCCG TGTGCTTTGA AAAGCTCGAT 60
GTCACAGCCA AAGTCCTCCC TTGCCAGCAC ACCTTCTGCA AACCATGTCT CCAGAGGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003443	Anas platyrhynchos	59.94	1.00e-173	603.00
IUUC-Aca-004632	Anolis carolinensis	55.45	1.00e-172	600.00
IUUC-Bta-013400	Bos taurus	89.00	0.00e+00	1092.00
IUUC-Cel-018180	Caenorhabditis elegans	27.09	7.00e-21	96.30
IUUC-Cja-019686	Callithrix jacchus	75.85	0.00e+00	949.00
IUUC-Cfa-020893	Canis familiaris	93.69	0.00e+00	1194.00
IUUC-Cpo-021638	Cavia porcellus	81.31	0.00e+00	1036.00
IUUC-Csa-023846	Chlorocebus sabaeus	88.48	0.00e+00	1116.00
IUUC-Cho-024609	Choloepus hoffmanni	87.89	8.00e-170	590.00
IUUC-Dno-028940	Dasypus novemcinctus	86.22	0.00e+00	1099.00
IUUC-Dor-030491	Dipodomys ordii	78.12	5.00e-133	468.00
IUUC-Dse-031414	Dothistroma septosporum	34.33	3.00e-08	54.30
IUUC-Ete-032513	Echinops telfairi	85.04	0.00e+00	1062.00
IUUC-Eca-034241	Equus caballus	90.67	0.00e+00	1174.00
IUUC-Eeu-034636	Erinaceus europaeus	82.58	0.00e+00	962.00
IUUC-Fca-035862	Felis catus	90.68	0.00e+00	1150.00
IUUC-Gga-040748	Gallus gallus	54.38	1.00e-142	500.00
IUUC-Ggo-045267	Gorilla gorilla	87.79	0.00e+00	1131.00
IUUC-Hsa-045761	Homo sapiens	87.38	0.00e+00	1123.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	84.77	0.00e+00	1082.00
IUUC-Lch-050498	Latimeria chalumnae	43.68	1.00e-118	420.00
IUUC-Laf-054061	Loxodonta africana	78.10	0.00e+00	840.00
IUUC-Mcc-054746	Macaca mulatta	87.76	0.00e+00	1091.00
IUUC-Meu-056390	Macropus eugenii	59.27	8.00e-91	328.00
IUUC-Mga-059398	Meleagris gallopavo	65.15	8.00e-92	330.00
IUUC-Mmr-061390	Microcebus murinus	82.71	0.00e+00	890.00
IUUC-Mdo-062951	Monodelphis domestica	73.19	0.00e+00	980.00
IUUC-Mmu-063840	Mus musculus	79.01	0.00e+00	1017.00
IUUC-Mpu-065840	Mustela putorius furo	93.28	0.00e+00	1221.00
IUUC-Mlu-067378	Myotis lucifugus	86.69	0.00e+00	1084.00
IUUC-Nle-069535	Nomascus leucogenys	84.22	0.00e+00	1051.00
IUUC-Opr-070739	Ochotona princeps	81.21	0.00e+00	1033.00
IUUC-Oan-073468	Ornithorhynchus anatinus	66.58	0.00e+00	792.00
IUUC-Ocu-074343	Oryctolagus cuniculus	83.40	0.00e+00	1018.00
IUUC-Oga-088276	Otolemur garnettii	78.19	0.00e+00	983.00
IUUC-Oar-090315	Ovis aries	88.20	0.00e+00	1095.00
IUUC-Ptr-091119	Pan troglodytes	87.11	0.00e+00	1120.00
IUUC-Pan-092158	Papio anubis	89.12	0.00e+00	827.00
IUUC-Psi-092959	Pelodiscus sinensis	61.57	0.00e+00	747.00
IUUC-Pab-097675	Pongo abelii	87.65	0.00e+00	1110.00
IUUC-Pca-101021	Procavia capensis	79.48	0.00e+00	969.00
IUUC-Pva-102619	Pteropus vampyrus	89.01	0.00e+00	1085.00
IUUC-Rno-105918	Rattus norvegicus	78.88	0.00e+00	1024.00
IUUC-Sha-107391	Sarcophilus harrisii	69.37	0.00e+00	899.00
IUUC-Sar-113148	Sorex araneus	82.76	0.00e+00	653.00
IUUC-Ssc-116219	Sus scrofa	81.07	8.00e-128	449.00
IUUC-Tgu-116584	Taeniopygia guttata	57.18	1.00e-109	389.00
IUUC-Tsy-118968	Tarsius syrichta	83.78	7.00e-166	577.00
IUUC-Tbe-128007	Tupaia belangeri	89.19	0.00e+00	815.00
IUUC-Ttr-128499	Tursiops truncatus	86.83	0.00e+00	1130.00
IUUC-Vpa-130075	Vicugna pacos	80.75	4.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence