iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090315

Ensembl Protein ID

ENSOARP00000002481.1

UniProt Accession

W5NWD4; W5NWD4_SHEEP

Genbank Protein ID

ENSOARP00000002481

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01093339

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000002342.1	ENSOART00000002533.1	ENSOARP00000002481.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.70e-08	32.8	12	53
UBD/SH3	2.90e-31	107.4	386	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCLEKLDVTAKVLPCQHTFCKPCLQRI----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l+ y+a   deL l+kG+ v+v+   +   gWl+gv+  +g+ G+fP+n+v 
   Q: 386  NMFVALHAYSAHGPDELDLQKGEGVRVL--GKYQDGWLRGVSLVTGRVGIFPNNYVI 440
           7889************************..555679*******************96 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MDDVTLLDLL ECPVCLEKLD VTAKVLPCQH TFCKPCLQRI FKAHKELRCP ECRTLVFCSI 60
EALPANLLLV RLLDGVRAGQ GSGRGGSFRR PGVLTPQDGR RSRTHPRGPQ CSPFRLVPNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAAGCGGGC ATCCTGACGC TCTCAAGAAG CCCCGTCTCT ACCCCCGCTG GCTCAGCTGA 60
CCAGACCATG TGGACTCTGC CCCTCCAGGT CAGGACTGGA GTTTTAAAAT AAAATGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF13639--zf-RING_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	88.23	0.00e+00	1143.00
IUUC-Apl-003443	Anas platyrhynchos	60.99	2.00e-180	625.00
IUUC-Aca-004632	Anolis carolinensis	53.58	3.00e-175	608.00
IUUC-Bta-013400	Bos taurus	97.05	0.00e+00	1219.00
IUUC-Cel-018180	Caenorhabditis elegans	26.76	3.00e-22	100.00
IUUC-Cja-019686	Callithrix jacchus	75.17	0.00e+00	948.00
IUUC-Cfa-020893	Canis familiaris	89.16	0.00e+00	1138.00
IUUC-Cpo-021638	Cavia porcellus	80.70	0.00e+00	1040.00
IUUC-Csa-023846	Chlorocebus sabaeus	87.11	0.00e+00	1134.00
IUUC-Cho-024609	Choloepus hoffmanni	88.72	0.00e+00	634.00
IUUC-Cin-025274	Ciona intestinalis	47.35	8.00e-64	236.00
IUUC-Csv-026136	Ciona savignyi	44.68	3.00e-63	235.00
IUUC-Dno-028940	Dasypus novemcinctus	86.50	0.00e+00	1134.00
IUUC-Dor-030491	Dipodomys ordii	74.29	1.00e-122	433.00
IUUC-Dse-031414	Dothistroma septosporum	32.84	6.00e-08	53.50
IUUC-Dme-032207	Drosophila melanogaster	41.45	1.00e-56	214.00
IUUC-Ete-032513	Echinops telfairi	84.92	0.00e+00	1094.00
IUUC-Eca-034241	Equus caballus	90.23	0.00e+00	1197.00
IUUC-Eeu-034636	Erinaceus europaeus	81.41	0.00e+00	976.00
IUUC-Fca-035862	Felis catus	86.47	0.00e+00	1129.00
IUUC-Gga-040748	Gallus gallus	55.34	1.00e-154	540.00
IUUC-Ggo-045267	Gorilla gorilla	87.52	0.00e+00	1134.00
IUUC-Hsa-045761	Homo sapiens	87.25	0.00e+00	1125.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	84.53	0.00e+00	1099.00
IUUC-Lch-050498	Latimeria chalumnae	45.32	8.00e-126	444.00
IUUC-Laf-054061	Loxodonta africana	79.84	0.00e+00	858.00
IUUC-Mcc-054746	Macaca mulatta	86.41	0.00e+00	1087.00
IUUC-Meu-056390	Macropus eugenii	57.53	2.00e-88	320.00
IUUC-Mmr-061390	Microcebus murinus	81.83	0.00e+00	866.00
IUUC-Mdo-062951	Monodelphis domestica	72.26	0.00e+00	998.00
IUUC-Mmu-063840	Mus musculus	79.10	0.00e+00	1046.00
IUUC-Mpu-065840	Mustela putorius furo	87.80	0.00e+00	1174.00
IUUC-Mlu-067378	Myotis lucifugus	88.15	0.00e+00	1122.00
IUUC-Nle-069535	Nomascus leucogenys	83.31	0.00e+00	1051.00
IUUC-Opr-070739	Ochotona princeps	80.60	0.00e+00	1030.00
IUUC-Oan-073468	Ornithorhynchus anatinus	66.53	0.00e+00	810.00
IUUC-Ocu-074343	Oryctolagus cuniculus	83.18	0.00e+00	1027.00
IUUC-Oga-088276	Otolemur garnettii	79.10	0.00e+00	1017.00
IUUC-Ptr-091119	Pan troglodytes	86.97	0.00e+00	1123.00
IUUC-Pan-092158	Papio anubis	88.72	0.00e+00	837.00
IUUC-Psi-092959	Pelodiscus sinensis	62.78	0.00e+00	779.00
IUUC-Pab-097675	Pongo abelii	86.97	0.00e+00	1108.00
IUUC-Pca-101021	Procavia capensis	78.08	0.00e+00	997.00
IUUC-Pva-102619	Pteropus vampyrus	88.20	0.00e+00	1121.00
IUUC-Rno-105918	Rattus norvegicus	79.51	0.00e+00	1056.00
IUUC-Sha-107391	Sarcophilus harrisii	68.38	0.00e+00	933.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	43.10	4.00e-10	59.30
IUUC-Sar-113148	Sorex araneus	82.70	0.00e+00	671.00
IUUC-Ssc-116219	Sus scrofa	82.95	5.00e-131	460.00
IUUC-Tgu-116584	Taeniopygia guttata	57.58	9.00e-118	416.00
IUUC-Tsy-118968	Tarsius syrichta	82.90	7.00e-175	607.00
IUUC-Tbe-128007	Tupaia belangeri	89.54	0.00e+00	832.00
IUUC-Ttr-128499	Tursiops truncatus	89.77	0.00e+00	1187.00
IUUC-Vpa-130075	Vicugna pacos	85.23	1.00e-81	297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence