iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089870

Ensembl Protein ID

ENSOARP00000013510.1

UniProt Accession

W5PST1; W5PST1_SHEEP

Genbank Protein ID

ENSOARP00000013510

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01023899

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012605.1	ENSOART00000013710.1	ENSOARP00000013510.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	87.95	0.00e+00	1846.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.11	1.00e-42	169.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MRRFKRKHLT AIECQHLAQS HLAASQSFGQ RWTSRDPNHG LYPRPRTKRG TRGRGCLRYS 60
RDFFLAGQQQ CTNDMAKSNS VGQDSPKDSE DEMIFEAGSP CALPPGGDGD TRLHSPGSAL 120

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Nucleotide Sequence
(Fasta)

GCTGGTGGAG GAAGTCCACG GCCTGCAGGG GCTCTCACTG CCCCTGGGAA GCCGCGACCG 60
GGAACCCGGG TGGCCCGGGA CCTGAGGCGG CGGCGGCGAG AGCCCTGATG CAGATCGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

KEGG

oas:101112918

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	47.83	1.00e-04	42.70
IUUC-Aml-001396	Ailuropoda melanoleuca	89.96	0.00e+00	1900.00
IUUC-Atr-002826	Amborella trichopoda	40.00	7.00e-04	40.00
IUUC-Apl-003317	Anas platyrhynchos	48.07	0.00e+00	912.00
IUUC-Aca-004498	Anolis carolinensis	53.17	0.00e+00	939.00
IUUC-Ath-007293	Arabidopsis thaliana	37.68	4.00e-03	37.40
IUUC-Ani-009226	Aspergillus nidulans	28.24	1.00e-06	49.30
IUUC-Ate-010526	Aspergillus terreus	39.71	1.00e-03	39.30
IUUC-Ame-011808	Astyanax mexicanus	58.42	1.00e-132	466.00
IUUC-Bta-013250	Bos taurus	96.85	0.00e+00	2060.00
IUUC-Bol-015348	Brassica oleracea	37.68	4.00e-03	37.70
IUUC-Cja-019638	Callithrix jacchus	87.86	0.00e+00	1894.00
IUUC-Cfa-020195	Canis familiaris	90.64	0.00e+00	1811.00
IUUC-Cpo-022269	Cavia porcellus	83.84	0.00e+00	1751.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	3.00e-08	54.30
IUUC-Csa-024060	Chlorocebus sabaeus	89.20	0.00e+00	1702.00
IUUC-Cho-025003	Choloepus hoffmanni	88.64	0.00e+00	701.00
IUUC-Cin-025694	Ciona intestinalis	27.14	4.00e-28	119.00
IUUC-Dre-028083	Danio rerio	48.99	0.00e+00	842.00
IUUC-Dno-029203	Dasypus novemcinctus	84.34	0.00e+00	1699.00
IUUC-Dor-030477	Dipodomys ordii	95.91	0.00e+00	780.00
IUUC-Ete-032861	Echinops telfairi	84.89	0.00e+00	1786.00
IUUC-Eca-033205	Equus caballus	90.25	0.00e+00	1947.00
IUUC-Eeu-034784	Erinaceus europaeus	85.37	0.00e+00	1183.00
IUUC-Fca-035797	Felis catus	89.89	0.00e+00	1909.00
IUUC-Gmo-038855	Gadus morhua	46.28	3.00e-120	426.00
IUUC-Gga-040326	Gallus gallus	50.19	0.00e+00	963.00
IUUC-Gac-042240	Gasterosteus aculeatus	45.92	0.00e+00	718.00
IUUC-Ggo-045050	Gorilla gorilla	84.43	0.00e+00	1743.00
IUUC-Hsa-046650	Homo sapiens	87.95	0.00e+00	1833.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	93.80	0.00e+00	756.00
IUUC-Lch-050231	Latimeria chalumnae	48.54	7.00e-155	541.00
IUUC-Loc-051884	Lepisosteus oculatus	49.30	0.00e+00	967.00
IUUC-Lma-053267	Leptosphaeria maculans	25.45	3.00e-03	38.10
IUUC-Laf-053843	Loxodonta africana	86.90	0.00e+00	1847.00
IUUC-Mcc-055570	Macaca mulatta	88.24	0.00e+00	1863.00
IUUC-Meu-056798	Macropus eugenii	66.92	2.00e-150	526.00
IUUC-Mtr-057915	Medicago truncatula	36.76	6.00e-04	40.40
IUUC-Mga-059648	Meleagris gallopavo	51.08	0.00e+00	917.00
IUUC-Mvi-060236	Microbotryum violaceum	38.71	2.00e-04	41.60
IUUC-Mmr-060757	Microcebus murinus	86.45	0.00e+00	1789.00
IUUC-Mdo-061913	Monodelphis domestica	68.52	0.00e+00	1353.00
IUUC-Mmu-064337	Mus musculus	86.23	0.00e+00	1856.00
IUUC-Mpu-066483	Mustela putorius furo	88.43	0.00e+00	1900.00
IUUC-Mlu-068204	Myotis lucifugus	83.03	0.00e+00	1759.00
IUUC-Ncr-068735	Neurospora crassa	25.36	8.00e-05	43.10
IUUC-Nle-070053	Nomascus leucogenys	87.86	0.00e+00	1808.00
IUUC-Opr-070588	Ochotona princeps	83.08	0.00e+00	1738.00
IUUC-Ont-072655	Oreochromis niloticus	46.36	0.00e+00	744.00
IUUC-Oan-073351	Ornithorhynchus anatinus	61.62	0.00e+00	1269.00
IUUC-Ocu-074465	Oryctolagus cuniculus	87.02	0.00e+00	1785.00
IUUC-Ogu-078861	Oryza glumaepatula	48.72	1.00e-03	37.70
IUUC-Oin-079176	Oryza indica	24.24	3.00e-05	43.50
IUUC-Oni-082634	Oryza nivara	48.72	1.00e-03	38.10
IUUC-Opu-083155	Oryza punctata	47.50	2.00e-03	38.10
IUUC-Oru-084992	Oryza rufipogon	48.72	1.00e-03	38.10
IUUC-Olu-087831	Ostreococcus lucimarinus	30.49	3.00e-62	234.00
IUUC-Oga-089088	Otolemur garnettii	85.85	0.00e+00	1776.00
IUUC-Ptr-090957	Pan troglodytes	87.83	0.00e+00	1811.00
IUUC-Pan-092632	Papio anubis	87.95	0.00e+00	1811.00
IUUC-Psi-093035	Pelodiscus sinensis	54.43	0.00e+00	1108.00
IUUC-Pno-094870	Phaeosphaeria nodorum	24.56	2.00e-04	41.60
IUUC-Ppa-095660	Physcomitrella patens	38.46	7.00e-04	40.00
IUUC-Pfo-096902	Poecilia formosa	44.18	0.00e+00	677.00
IUUC-Pab-098206	Pongo abelii	87.78	0.00e+00	1703.00
IUUC-Pop-098801	Populus trichocarpa	34.72	6.00e-04	40.00
IUUC-Pca-100238	Procavia capensis	81.45	0.00e+00	1713.00
IUUC-Ppe-101748	Prunus persica	35.94	8.00e-03	36.60
IUUC-Pva-103182	Pteropus vampyrus	87.76	0.00e+00	1831.00
IUUC-Pte-104033	Pyrenophora teres	23.57	1.00e-03	39.30
IUUC-Pyt-104599	Pyrenophora triticirepentis	23.57	1.00e-03	39.30
IUUC-Rno-105141	Rattus norvegicus	86.81	0.00e+00	1868.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	3.00e-03	37.40
IUUC-Sha-106827	Sarcophilus harrisii	66.54	0.00e+00	1415.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.65	5.00e-41	162.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.11	2.00e-42	167.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	25.00	3.00e-03	37.70
IUUC-Sly-111170	Solanum lycopersicum	33.33	6.70e-02	32.30
IUUC-Sre-115025	Sporisorium reilianum	32.92	1.00e-38	155.00
IUUC-Ssc-116188	Sus scrofa	95.07	0.00e+00	1268.00
IUUC-Tgu-116612	Taeniopygia guttata	57.47	3.00e-157	548.00
IUUC-Tsy-119560	Tarsius syrichta	80.65	6.00e-113	402.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.89	0.00e+00	713.00
IUUC-Tca-121338	Theobroma cacao	30.36	1.30e-02	35.80
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tme-127009	Tuber melanosporum	26.85	2.00e-03	38.50
IUUC-Tbe-127431	Tupaia belangeri	86.70	0.00e+00	1558.00
IUUC-Ttr-128744	Tursiops truncatus	89.11	0.00e+00	1850.00
IUUC-Uma-129536	Ustilago maydis	33.86	3.00e-40	160.00
IUUC-Vpa-130123	Vicugna pacos	77.47	2.00e-101	363.00
IUUC-Vvi-131025	Vitis vinifera	37.50	4.00e-03	37.70
IUUC-Xtr-132902	Xenopus tropicalis	58.93	0.00e+00	1003.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence