iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035398

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02155983

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008668.2	ENSFCAT00000008670.2	ENSFCAP00000008034.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.30e-09	36.8	258	296
UBD/Alpha-Helix/CUE	1.80e-11	43.8	373	414

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 258  CAICWDSMQA-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 296
           ********99.******************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 373  QLNAMAHQIQEMFPQVPYHLVLQDL-QLTRSVEITTDNILEGR 414
           5889*********************.***************95 PP

Organism

Felis catus

Protein Sequence
(Fasta)

VQVLVNTACC VLMLVAKLIQ CIVFGPLRVS ERQHLKDKFW NFIFYKFIFI FGVLNVQTVE 60
EVVMWCLWFA GLVFLHLMVQ LCKDRFEYLS FSPTTPMSSH GRVLSLLIAM LLSCCGLAVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACAGGTTC TAGTAAATAC TGCTTGCTGT GTTTTGATGT TGGTGGCTAA ACTAATCCAG 60
TGTATTGTGT TTGGCCCTCT TCGAGTGAGT GAGAGACAGG TAAGTCCAAA TGGCAAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	96.88	0.00e+00	963.00
IUUC-Apl-003404	Anas platyrhynchos	90.39	0.00e+00	899.00
IUUC-Aca-004559	Anolis carolinensis	87.40	0.00e+00	846.00
IUUC-Ame-011640	Astyanax mexicanus	76.37	0.00e+00	739.00
IUUC-Bta-012980	Bos taurus	96.48	0.00e+00	1004.00
IUUC-Cel-018598	Caenorhabditis elegans	23.70	2.00e-30	126.00
IUUC-Cja-019577	Callithrix jacchus	95.70	0.00e+00	996.00
IUUC-Cfa-020793	Canis familiaris	97.65	0.00e+00	1009.00
IUUC-Cpo-022387	Cavia porcellus	96.29	0.00e+00	969.00
IUUC-Csa-023168	Chlorocebus sabaeus	95.90	0.00e+00	1000.00
IUUC-Cho-024433	Choloepus hoffmanni	96.22	0.00e+00	846.00
IUUC-Cin-025215	Ciona intestinalis	48.94	3.00e-139	488.00
IUUC-Csv-026133	Ciona savignyi	48.84	2.00e-127	449.00
IUUC-Dre-027594	Danio rerio	74.51	0.00e+00	705.00
IUUC-Dno-029407	Dasypus novemcinctus	97.26	0.00e+00	974.00
IUUC-Dor-030961	Dipodomys ordii	96.47	0.00e+00	987.00
IUUC-Ete-032962	Echinops telfairi	86.67	0.00e+00	811.00
IUUC-Eca-033683	Equus caballus	95.50	0.00e+00	964.00
IUUC-Eeu-034515	Erinaceus europaeus	100.00	5.00e-80	291.00
IUUC-Fal-036758	Ficedula albicollis	82.64	0.00e+00	853.00
IUUC-Gmo-039014	Gadus morhua	72.96	0.00e+00	689.00
IUUC-Gga-040575	Gallus gallus	90.62	0.00e+00	937.00
IUUC-Gac-041414	Gasterosteus aculeatus	71.90	0.00e+00	671.00
IUUC-Gma-044284	Glycine max	27.47	2.00e-28	120.00
IUUC-Hsa-046272	Homo sapiens	95.70	0.00e+00	996.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	96.29	0.00e+00	970.00
IUUC-Lch-050491	Latimeria chalumnae	80.62	0.00e+00	798.00
IUUC-Loc-052758	Lepisosteus oculatus	79.96	0.00e+00	756.00
IUUC-Laf-053452	Loxodonta africana	96.88	0.00e+00	976.00
IUUC-Mcc-055820	Macaca mulatta	96.20	0.00e+00	979.00
IUUC-Meu-056726	Macropus eugenii	86.89	0.00e+00	753.00
IUUC-Mga-059937	Meleagris gallopavo	90.62	0.00e+00	905.00
IUUC-Mmr-060730	Microcebus murinus	96.68	0.00e+00	967.00
IUUC-Mdo-062771	Monodelphis domestica	93.75	0.00e+00	971.00
IUUC-Mmu-064219	Mus musculus	96.09	0.00e+00	994.00
IUUC-Mpu-066796	Mustela putorius furo	97.80	0.00e+00	993.00
IUUC-Mlu-068189	Myotis lucifugus	94.92	0.00e+00	948.00
IUUC-Nle-069239	Nomascus leucogenys	95.90	0.00e+00	999.00
IUUC-Opr-070702	Ochotona princeps	92.70	9.00e-128	450.00
IUUC-Ont-072033	Oreochromis niloticus	74.90	0.00e+00	733.00
IUUC-Oan-073717	Ornithorhynchus anatinus	91.63	0.00e+00	857.00
IUUC-Ocu-074145	Oryctolagus cuniculus	95.12	0.00e+00	990.00
IUUC-Ogl-077929	Oryza glaberrima	53.49	8.00e-11	59.70
IUUC-Ola-087152	Oryzias latipes	72.22	0.00e+00	702.00
IUUC-Oga-088486	Otolemur garnettii	96.48	0.00e+00	968.00
IUUC-Oar-089310	Ovis aries	96.88	0.00e+00	1008.00
IUUC-Ptr-090649	Pan troglodytes	95.88	0.00e+00	996.00
IUUC-Pan-091692	Papio anubis	90.82	0.00e+00	935.00
IUUC-Psi-093064	Pelodiscus sinensis	94.22	0.00e+00	760.00
IUUC-Pma-094763	Petromyzon marinus	76.23	4.00e-93	333.00
IUUC-Ppa-095969	Physcomitrella patens	29.87	1.00e-35	144.00
IUUC-Pfo-096810	Poecilia formosa	72.96	0.00e+00	707.00
IUUC-Pab-097859	Pongo abelii	96.00	0.00e+00	979.00
IUUC-Pop-099576	Populus trichocarpa	27.35	2.00e-28	120.00
IUUC-Pca-100344	Procavia capensis	94.75	0.00e+00	948.00
IUUC-Pva-103114	Pteropus vampyrus	66.80	2.00e-177	615.00
IUUC-Rno-105880	Rattus norvegicus	94.14	0.00e+00	969.00
IUUC-Sha-107015	Sarcophilus harrisii	92.97	0.00e+00	961.00
IUUC-Sar-113397	Sorex araneus	97.30	0.00e+00	748.00
IUUC-Ssc-115988	Sus scrofa	95.00	1.00e-136	478.00
IUUC-Tgu-116717	Taeniopygia guttata	91.02	0.00e+00	889.00
IUUC-Tru-117805	Takifugu rubripes	74.42	0.00e+00	717.00
IUUC-Tsy-119442	Tarsius syrichta	90.00	0.00e+00	897.00
IUUC-Tni-119777	Tetraodon nigroviridis	71.39	3.00e-164	571.00
IUUC-Tca-121783	Theobroma cacao	26.90	2.00e-27	117.00
IUUC-Tbe-127322	Tupaia belangeri	67.77	6.00e-111	394.00
IUUC-Ttr-128181	Tursiops truncatus	96.47	0.00e+00	1000.00
IUUC-Vpa-130483	Vicugna pacos	85.24	0.00e+00	650.00
IUUC-Xtr-132614	Xenopus tropicalis	80.27	0.00e+00	746.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence