iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048370

Ensembl Protein ID

ENSSTOP00000001578.2

UniProt Accession

I3LZ64; I3LZ64_ICTTR

Genbank Protein ID

ENSSTOP00000001578

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01046153

Gene Name

ARIH2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000001766.2	ENSSTOT00000001768.2	ENSSTOP00000001578.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.70e-55	188.0	63	250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + +sc+a++cp +++e+ +  ll++eel+++y+++l++++ve++++l++
   Q: 63   CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELKDKYRRYLFRDYVESHYQLQL 151
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 152  CPGADCPMVIRVQEP-RARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 237
           **************7.99*************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 238  QCSKCKHDFCWMC 250
           ************* PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MTSLASVLKV SHSVAKLILV NFHWQVSEIL DRYKSNSSQL LVEARVQPNP SKHVPTTHPP 60
HHCAVCMQFV RKENLLSLAC QHQFCRSCWE QHCSVLVKDG VGVGVSCMAQ DCPLRTPEDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAGAAGA CAAAAACACT AATGCATTTG AGAAAGCGGT AAAGTTTGGG GGGAGGGAGA 60
GAAAGCAACT CCTTTCCTGA CCTGCAACTT GACTGGATGC TAAGATGTCT GTGGACATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000970	Aegilops tauschii	28.22	3.00e-43	169.00
IUUC-Aml-001557	Ailuropoda melanoleuca	98.80	0.00e+00	843.00
IUUC-Atr-002495	Amborella trichopoda	31.34	1.00e-49	191.00
IUUC-Apl-003878	Anas platyrhynchos	94.00	0.00e+00	803.00
IUUC-Aca-004865	Anolis carolinensis	93.29	0.00e+00	794.00
IUUC-Aly-006224	Arabidopsis lyrata	30.58	7.00e-58	218.00
IUUC-Ath-006859	Arabidopsis thaliana	30.39	8.00e-56	211.00
IUUC-Ago-007926	Ashbya gossypii	25.80	1.00e-41	164.00
IUUC-Bta-012901	Bos taurus	98.56	0.00e+00	840.00
IUUC-Bdi-014714	Brachypodium distachyon	30.81	1.00e-51	197.00
IUUC-Bol-015971	Brassica oleracea	30.63	6.00e-57	214.00
IUUC-Bra-017081	Brassica rapa	30.23	3.00e-57	216.00
IUUC-Cel-018334	Caenorhabditis elegans	50.24	2.00e-125	441.00
IUUC-Cja-019728	Callithrix jacchus	98.80	0.00e+00	842.00
IUUC-Cfa-020953	Canis familiaris	98.80	0.00e+00	843.00
IUUC-Cpo-021445	Cavia porcellus	99.04	0.00e+00	845.00
IUUC-Cre-022815	Chlamydomonas reinhardtii	29.27	3.00e-51	196.00
IUUC-Csa-023769	Chlorocebus sabaeus	98.56	0.00e+00	843.00
IUUC-Cho-024650	Choloepus hoffmanni	85.61	0.00e+00	696.00
IUUC-Cin-025577	Ciona intestinalis	56.76	9.00e-143	499.00
IUUC-Csv-025849	Ciona savignyi	56.10	1.00e-120	426.00
IUUC-Dre-028490	Danio rerio	85.65	0.00e+00	737.00
IUUC-Dno-029942	Dasypus novemcinctus	97.84	0.00e+00	835.00
IUUC-Dor-030134	Dipodomys ordii	84.98	6.00e-151	526.00
IUUC-Dme-031853	Drosophila melanogaster	56.49	2.00e-142	498.00
IUUC-Ete-032355	Echinops telfairi	89.93	0.00e+00	747.00
IUUC-Eca-033440	Equus caballus	98.80	0.00e+00	843.00
IUUC-Eeu-035230	Erinaceus europaeus	89.36	4.00e-115	407.00
IUUC-Fca-036308	Felis catus	91.15	0.00e+00	769.00
IUUC-Fal-036974	Ficedula albicollis	94.00	0.00e+00	803.00
IUUC-Gmo-038642	Gadus morhua	87.50	0.00e+00	708.00
IUUC-Gga-041019	Gallus gallus	94.00	0.00e+00	803.00
IUUC-Gac-042014	Gasterosteus aculeatus	83.57	0.00e+00	722.00
IUUC-Gma-042954	Glycine max	30.50	4.00e-54	205.00
IUUC-Ggo-045329	Gorilla gorilla	99.04	0.00e+00	845.00
IUUC-Hsa-046712	Homo sapiens	99.04	0.00e+00	845.00
IUUC-Hvu-047322	Hordeum vulgare	31.25	3.00e-54	206.00
IUUC-Lch-049584	Latimeria chalumnae	87.32	0.00e+00	747.00
IUUC-Lpe-051492	Leersia perrieri	29.22	1.00e-54	207.00
IUUC-Loc-051826	Lepisosteus oculatus	85.77	5.00e-142	496.00
IUUC-Laf-054567	Loxodonta africana	98.80	0.00e+00	805.00
IUUC-Mcc-054919	Macaca mulatta	98.56	0.00e+00	843.00
IUUC-Meu-056332	Macropus eugenii	91.13	0.00e+00	766.00
IUUC-Mtr-058263	Medicago truncatula	30.15	6.00e-54	205.00
IUUC-Mga-060132	Meleagris gallopavo	94.03	0.00e+00	806.00
IUUC-Mmr-061599	Microcebus murinus	94.50	0.00e+00	792.00
IUUC-Mdo-062186	Monodelphis domestica	95.17	0.00e+00	801.00
IUUC-Mmu-064271	Mus musculus	98.08	0.00e+00	840.00
IUUC-Mac-065497	Musa acuminata	29.40	2.00e-53	202.00
IUUC-Mpu-066827	Mustela putorius furo	96.43	0.00e+00	825.00
IUUC-Mlu-067528	Myotis lucifugus	97.36	0.00e+00	798.00
IUUC-Nle-068995	Nomascus leucogenys	99.04	0.00e+00	845.00
IUUC-Opr-070518	Ochotona princeps	98.08	0.00e+00	802.00
IUUC-Ont-071650	Oreochromis niloticus	86.52	0.00e+00	738.00
IUUC-Oan-073676	Ornithorhynchus anatinus	94.12	0.00e+00	753.00
IUUC-Ocu-073761	Oryctolagus cuniculus	99.28	0.00e+00	846.00
IUUC-Oba-075918	Oryza barthii	29.70	8.00e-53	201.00
IUUC-Obr-076705	Oryza brachyantha	30.73	5.00e-57	215.00
IUUC-Ogl-077640	Oryza glaberrima	30.35	5.00e-53	202.00
IUUC-Ogu-079025	Oryza glumaepatula	29.50	3.00e-55	209.00
IUUC-Oin-079448	Oryza indica	30.35	1.00e-53	204.00
IUUC-Olo-080774	Oryza longistaminata	30.41	3.00e-49	189.00
IUUC-Ome-081470	Oryza meridionalis	29.98	5.00e-53	201.00
IUUC-Oni-082202	Oryza nivara	29.93	7.00e-50	191.00
IUUC-Opu-084059	Oryza punctata	29.72	6.00e-56	211.00
IUUC-Oru-084181	Oryza rufipogon	29.50	2.00e-55	209.00
IUUC-Osa-086069	Oryza sativa	29.50	7.00e-55	208.00
IUUC-Ola-087204	Oryzias latipes	82.64	0.00e+00	715.00
IUUC-Olu-087826	Ostreococcus lucimarinus	30.60	1.00e-45	177.00
IUUC-Oga-088098	Otolemur garnettii	98.80	0.00e+00	840.00
IUUC-Oar-089205	Ovis aries	98.56	0.00e+00	840.00
IUUC-Ptr-091514	Pan troglodytes	99.04	0.00e+00	845.00
IUUC-Pan-092493	Papio anubis	92.97	0.00e+00	797.00
IUUC-Psi-093024	Pelodiscus sinensis	87.78	3.00e-92	330.00
IUUC-Ppa-095554	Physcomitrella patens	29.26	9.00e-56	211.00
IUUC-Pfo-097256	Poecilia formosa	85.92	0.00e+00	732.00
IUUC-Pab-098504	Pongo abelii	89.93	0.00e+00	744.00
IUUC-Pop-099547	Populus trichocarpa	31.36	5.00e-55	208.00
IUUC-Pca-100700	Procavia capensis	89.69	0.00e+00	738.00
IUUC-Ppe-101468	Prunus persica	31.23	1.00e-55	210.00
IUUC-Pva-103105	Pteropus vampyrus	97.84	0.00e+00	829.00
IUUC-Rno-105289	Rattus norvegicus	98.32	0.00e+00	841.00
IUUC-Sha-107417	Sarcophilus harrisii	95.68	0.00e+00	786.00
IUUC-Smo-109424	Selaginella moellendorffii	30.13	1.00e-53	203.00
IUUC-Sit-110645	Setaria italica	31.06	2.00e-55	209.00
IUUC-Sly-111454	Solanum lycopersicum	30.50	1.00e-55	210.00
IUUC-Stu-112533	Solanum tuberosum	29.55	7.00e-55	207.00
IUUC-Sar-113042	Sorex araneus	98.08	0.00e+00	835.00
IUUC-Sbi-114839	Sorghum bicolor	30.81	1.00e-54	207.00
IUUC-Ssc-115362	Sus scrofa	98.80	0.00e+00	842.00
IUUC-Tgu-117469	Taeniopygia guttata	93.65	0.00e+00	755.00
IUUC-Tru-117976	Takifugu rubripes	83.29	0.00e+00	731.00
IUUC-Tsy-118876	Tarsius syrichta	79.19	1.00e-77	283.00
IUUC-Tni-119831	Tetraodon nigroviridis	83.06	0.00e+00	728.00
IUUC-Tca-121326	Theobroma cacao	30.57	1.00e-58	220.00
IUUC-Tae-123155	Triticum aestivum	31.31	2.00e-54	206.00
IUUC-Tur-126320	Triticum urartu	28.71	1.00e-42	167.00
IUUC-Tbe-127386	Tupaia belangeri	89.34	3.00e-131	461.00
IUUC-Ttr-128315	Tursiops truncatus	98.80	0.00e+00	842.00
IUUC-Vpa-130383	Vicugna pacos	89.69	0.00e+00	743.00
IUUC-Vvi-131543	Vitis vinifera	29.70	1.00e-55	210.00
IUUC-Xtr-132945	Xenopus tropicalis	92.57	0.00e+00	787.00
IUUC-Xma-134312	Xiphophorus maculatus	82.99	0.00e+00	724.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence