iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065772

Ensembl Protein ID

ENSMPUP00000010731.1

UniProt Accession

M3YHC4; M3YHC4_MUSPF

Genbank Protein ID

ENSMPUP00000010731

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01045703

Gene Name

USP33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010819.1	ENSMPUT00000010910.1	ENSMPUP00000010731.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.00e-105	351.1	1	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 12   mNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEflafl 99
           mN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+qqDaqEfl++l
   Q: 1    MNAALQALSNCPPLTQFFLH-----CGGLARTDKKPAICKSYLKLMTELWhKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCL 84
           9*******************.....999999*******************99************************************* PP
   S: 100  ldqleeelkk........eknkpkeeeeeedkselsde................................................... 129
           +d l+eelk+         ++ + ee++eedks+++ +                                                   
   Q: 85   MDLLHEELKEqvmeveedPQTITAEETMEEDKSQSDVDfqscescsssdkaenengsrgfsednnettmliqddennsemakdwqkekm 173
           ********8889988877667777777777777777669************************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 174  cnkinkvnsegeldkdrdsvsetvdlnnqetvkvqihsraseyitdvhlndlstsqilpsnegvnprlsasppksgnlwpglaathkka 262
           ***************************************************************************************** PP
   S: 130  ......aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........................... 185
                 +++k++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+                           
   Q: 263  qsapspKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhssshptsivkagscgeayapqgwiaf 351
           *********************************************************99888*************************** PP
   S: 186  ......................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
                                 +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L++hLkRf  ++e ++++ki+++
   Q: 352  fmeyvkrfvvscvpswfwgpivTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF--RHELMFSTKISTH 438
           **************************************************************************..9999********* PP
   S: 253  vefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           v+fple Ldl+pf+++++  q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v++   ++aYvlfY++
   Q: 439  VSFPLEgLDLQPFLAKDSPVQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNHhWYEFDDQSVTEVSESTVQN---AEAYVLFYRK 520
           ****************77776..9**************************76657*******************...********98 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MNAALQALSN CPPLTQFFLH CGGLARTDKK PAICKSYLKL MTELWHKSRP GSVVPTTLFQ 60
GIKTVNPTFR GYSQQDAQEF LRCLMDLLHE ELKEQVMEVE EDPQTITAEE TMEEDKSQSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTTTAAAA TACCGAGCAA TACAACATTA AAAACTCCTC TGGTTGCTGT ATTTGATGAT 60
TTGGACATAG AAGTGGAAGA AGAAGATGAA CTTAAGGCAA GAGGTAAAAT AATTCTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001742	Ailuropoda melanoleuca	98.01	0.00e+00	1508.00
IUUC-Apl-003987	Anas platyrhynchos	82.00	0.00e+00	1225.00
IUUC-Aca-004713	Anolis carolinensis	76.80	0.00e+00	1148.00
IUUC-Bta-013132	Bos taurus	97.19	0.00e+00	1498.00
IUUC-Cja-018811	Callithrix jacchus	96.93	0.00e+00	1492.00
IUUC-Cfa-021158	Canis familiaris	96.94	0.00e+00	1496.00
IUUC-Cpo-021910	Cavia porcellus	87.60	0.00e+00	1291.00
IUUC-Csa-023130	Chlorocebus sabaeus	97.06	0.00e+00	1493.00
IUUC-Cho-024383	Choloepus hoffmanni	79.67	1.00e-122	433.00
IUUC-Csv-025889	Ciona savignyi	43.87	2.00e-35	141.00
IUUC-Dno-029416	Dasypus novemcinctus	94.52	0.00e+00	1418.00
IUUC-Ete-032994	Echinops telfairi	92.03	0.00e+00	693.00
IUUC-Eca-034248	Equus caballus	96.93	0.00e+00	1494.00
IUUC-Eeu-035357	Erinaceus europaeus	78.74	0.00e+00	1122.00
IUUC-Fca-036013	Felis catus	96.93	0.00e+00	1489.00
IUUC-Fal-037509	Ficedula albicollis	81.20	0.00e+00	1237.00
IUUC-Gga-040647	Gallus gallus	81.60	0.00e+00	1230.00
IUUC-Hsa-045694	Homo sapiens	96.93	0.00e+00	1492.00
IUUC-Itr-049041	Ictidomys tridecemlineatus	96.40	0.00e+00	1465.00
IUUC-Lch-050400	Latimeria chalumnae	71.49	0.00e+00	1068.00
IUUC-Loc-052616	Lepisosteus oculatus	72.41	0.00e+00	1118.00
IUUC-Laf-053493	Loxodonta africana	95.47	0.00e+00	1477.00
IUUC-Mcc-055542	Macaca mulatta	97.19	0.00e+00	1496.00
IUUC-Meu-056645	Macropus eugenii	78.18	0.00e+00	1155.00
IUUC-Mga-060019	Meleagris gallopavo	81.65	0.00e+00	1239.00
IUUC-Mmr-061241	Microcebus murinus	92.65	0.00e+00	1415.00
IUUC-Mmu-063786	Mus musculus	92.78	0.00e+00	1409.00
IUUC-Mlu-067732	Myotis lucifugus	95.21	0.00e+00	1474.00
IUUC-Nle-069528	Nomascus leucogenys	96.12	0.00e+00	1496.00
IUUC-Opr-070606	Ochotona princeps	91.99	0.00e+00	1315.00
IUUC-Ont-071495	Oreochromis niloticus	70.69	0.00e+00	1069.00
IUUC-Oan-073695	Ornithorhynchus anatinus	86.19	0.00e+00	801.00
IUUC-Ocu-074457	Oryctolagus cuniculus	96.16	0.00e+00	1486.00
IUUC-Ola-086739	Oryzias latipes	70.47	0.00e+00	1110.00
IUUC-Oga-088720	Otolemur garnettii	95.73	0.00e+00	1480.00
IUUC-Oar-089921	Ovis aries	97.19	0.00e+00	1498.00
IUUC-Ptr-090526	Pan troglodytes	96.93	0.00e+00	1493.00
IUUC-Pan-092396	Papio anubis	96.80	0.00e+00	1487.00
IUUC-Psi-092971	Pelodiscus sinensis	83.22	0.00e+00	1277.00
IUUC-Pab-098740	Pongo abelii	96.66	0.00e+00	1510.00
IUUC-Pca-100598	Procavia capensis	82.93	0.00e+00	898.00
IUUC-Pva-102820	Pteropus vampyrus	96.24	0.00e+00	1281.00
IUUC-Rno-104894	Rattus norvegicus	92.12	0.00e+00	1416.00
IUUC-Sha-107244	Sarcophilus harrisii	78.09	0.00e+00	1175.00
IUUC-Sar-113665	Sorex araneus	95.72	0.00e+00	1496.00
IUUC-Ssc-115793	Sus scrofa	93.46	0.00e+00	1412.00
IUUC-Tgu-117487	Taeniopygia guttata	82.94	0.00e+00	1209.00
IUUC-Tsy-119598	Tarsius syrichta	88.28	0.00e+00	1261.00
IUUC-Tbe-128125	Tupaia belangeri	97.09	9.00e-102	364.00
IUUC-Ttr-128269	Tursiops truncatus	94.92	0.00e+00	1415.00
IUUC-Vpa-130598	Vicugna pacos	93.99	0.00e+00	1440.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence