iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060012

UUCD1 version

UUC-MeG-00046

Ensembl Protein ID

ENSMGAP00000000395.2

UniProt Accession

G1MQN2; G1MQN2_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000000983.2	ENSMGAT00000001032.2	ENSMGAP00000000395.2
ENSMGAG00000000983.2	ENSMGAT00000020112.1	ENSMGAP00000019416.1
ENSMGAG00000000983.2	ENSMGAT00000020739.1	ENSMGAP00000017524.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-18	66.3	66	129
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-10	40.3	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dvil+v+ +ef++h++vLaa+S +F+a+f ++l+e+  ++++ +k+v++e ++ ll++ Yt+k+
   Q: 66   TDVILCVDSREFSCHRVVLAAASNYFRAMFCNDLREKY-EEKIILKGVDAETMNILLDYTYTSKM 129
           7***********************************97.***********************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nc+gilr+Ad+++++ Lk++++++i+++F+
   Q: 165  PDNCVGILRLADAHSLHSLKQQVQNYIIQNFT 196
           89*****************************7 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

AGQNMGDTLE KSSEDAEFSL DNECSTKKMG ELVEVSSGEK IKFDDTGLSL VLQNGLENLR 60
LENSLTDVIL CVDSREFSCH RVVLAAASNY FRAMFCNDLR EKYEEKIILK GVDAETMNIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGCCAGA ACATGGGGGA CACGCTGGAG AAGAGCTCTG AGGACGCTGA GTTCTCCTTG 60
GACAATGAGT GCTCGACAAA AAAAATGGGG GAGCTGGTGG AGGTCTCCAG CGGTGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011498--Kelch_2
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
PF07646--Kelch_2

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	82.39	0.00e+00	1070.00
IUUC-Apl-003490	Anas platyrhynchos	95.42	0.00e+00	1212.00
IUUC-Aca-005136	Anolis carolinensis	81.67	0.00e+00	1053.00
IUUC-Ame-010886	Astyanax mexicanus	68.24	0.00e+00	832.00
IUUC-Bta-013473	Bos taurus	80.94	0.00e+00	1035.00
IUUC-Cja-018888	Callithrix jacchus	82.16	0.00e+00	1062.00
IUUC-Cpo-021761	Cavia porcellus	76.31	0.00e+00	949.00
IUUC-Csa-023206	Chlorocebus sabaeus	82.39	0.00e+00	1069.00
IUUC-Cin-025367	Ciona intestinalis	39.35	8.00e-125	440.00
IUUC-Csv-026076	Ciona savignyi	40.79	5.00e-119	421.00
IUUC-Dre-027948	Danio rerio	72.87	0.00e+00	895.00
IUUC-Dno-030045	Dasypus novemcinctus	81.58	0.00e+00	1062.00
IUUC-Dor-030839	Dipodomys ordii	76.27	0.00e+00	953.00
IUUC-Eca-033608	Equus caballus	82.39	0.00e+00	1049.00
IUUC-Eeu-034640	Erinaceus europaeus	81.34	0.00e+00	1062.00
IUUC-Fca-036065	Felis catus	81.91	0.00e+00	1068.00
IUUC-Fal-036949	Ficedula albicollis	94.65	0.00e+00	1184.00
IUUC-Gmo-039661	Gadus morhua	60.46	2.00e-172	598.00
IUUC-Gga-040740	Gallus gallus	97.71	0.00e+00	1237.00
IUUC-Gac-042413	Gasterosteus aculeatus	60.10	0.00e+00	760.00
IUUC-Ggo-045167	Gorilla gorilla	82.39	0.00e+00	1068.00
IUUC-Hsa-046120	Homo sapiens	82.39	0.00e+00	1068.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	82.23	0.00e+00	1070.00
IUUC-Lch-049709	Latimeria chalumnae	80.91	0.00e+00	1060.00
IUUC-Loc-052239	Lepisosteus oculatus	82.05	0.00e+00	979.00
IUUC-Laf-054511	Loxodonta africana	81.83	0.00e+00	1063.00
IUUC-Mcc-055109	Macaca mulatta	82.39	0.00e+00	1068.00
IUUC-Meu-056522	Macropus eugenii	67.65	3.00e-92	332.00
IUUC-Mmr-061364	Microcebus murinus	81.58	0.00e+00	1061.00
IUUC-Mdo-063033	Monodelphis domestica	77.67	0.00e+00	945.00
IUUC-Mmu-063880	Mus musculus	80.45	0.00e+00	1026.00
IUUC-Mlu-068233	Myotis lucifugus	82.07	0.00e+00	1063.00
IUUC-Opr-070638	Ochotona princeps	81.18	0.00e+00	747.00
IUUC-Ont-071960	Oreochromis niloticus	60.00	0.00e+00	764.00
IUUC-Oan-073406	Ornithorhynchus anatinus	77.58	0.00e+00	997.00
IUUC-Ocu-074612	Oryctolagus cuniculus	81.26	0.00e+00	1064.00
IUUC-Ola-087181	Oryzias latipes	58.24	0.00e+00	750.00
IUUC-Oga-088955	Otolemur garnettii	81.91	0.00e+00	1063.00
IUUC-Oar-089682	Ovis aries	80.94	0.00e+00	1035.00
IUUC-Ptr-090969	Pan troglodytes	82.39	0.00e+00	1069.00
IUUC-Pan-092289	Papio anubis	82.39	0.00e+00	1069.00
IUUC-Psi-093279	Pelodiscus sinensis	90.08	0.00e+00	1164.00
IUUC-Pab-097957	Pongo abelii	84.65	0.00e+00	815.00
IUUC-Pca-100619	Procavia capensis	79.32	0.00e+00	1049.00
IUUC-Pva-102533	Pteropus vampyrus	81.05	5.00e-179	620.00
IUUC-Rno-106111	Rattus norvegicus	80.45	0.00e+00	1053.00
IUUC-Sha-106716	Sarcophilus harrisii	77.72	0.00e+00	994.00
IUUC-Tgu-116839	Taeniopygia guttata	95.09	0.00e+00	1204.00
IUUC-Tru-117792	Takifugu rubripes	61.43	0.00e+00	741.00
IUUC-Tsy-119609	Tarsius syrichta	74.75	7.00e-129	453.00
IUUC-Tni-119682	Tetraodon nigroviridis	60.73	0.00e+00	742.00
IUUC-Tme-127039	Tuber melanosporum	30.46	1.00e-12	68.90
IUUC-Tbe-127961	Tupaia belangeri	78.07	0.00e+00	967.00
IUUC-Ttr-128917	Tursiops truncatus	79.77	0.00e+00	860.00
IUUC-Vpa-130721	Vicugna pacos	83.45	0.00e+00	744.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence