iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000001519.1	ENSOART00000001627.1	ENSOARP00000001584.1
ENSOARG00000001519.1	ENSOART00000001628.1	ENSOARP00000001585.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.20e-08	33.7	8	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliq 66
           ee  C+I l lM++ v +++G++y  ++I  ++++  +        +cP +r+p+  e+l Pn+ l +li+
   Q: 8    EEATCSICLHLMTNAVSISCGHSYCHACIVSFFENLYQmqpwlktfSCPQCRAPFNMESLRPNKQLGNLIE 78
           6889*****************************77777799*************************99996 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MASKKMREEA TCSICLHLMT NAVSISCGHS YCHACIVSFF ENLYQMQPWL KTFSCPQCRA 60
PFNMESLRPN KQLGNLIEVI KEMDQEMSCE EHGEKLHLFC EDEGQLICWL CDRGAQHKGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCCATGTT AAATCTCTGA AGTACAGAAG GTGAGGTGAG TGAAGGTCCA GGACAGGCGC 60
CCTGGGGGCT CAGAGGAGGG GAGGTCCTCC TTCCCTAGGA GCACAGCACC AGTGGCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR010908--Longin_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

KEGG

oas:101114398

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	77.83	0.00e+00	743.00
IUUC-Bta-012574	Bos taurus	96.09	0.00e+00	919.00
IUUC-Cja-019759	Callithrix jacchus	75.65	0.00e+00	677.00
IUUC-Cfa-020431	Canis familiaris	74.51	0.00e+00	697.00
IUUC-Cpo-022541	Cavia porcellus	64.79	0.00e+00	630.00
IUUC-Csa-023320	Chlorocebus sabaeus	74.35	0.00e+00	712.00
IUUC-Cho-024964	Choloepus hoffmanni	71.04	2.00e-128	451.00
IUUC-Dno-029741	Dasypus novemcinctus	67.10	1.00e-177	615.00
IUUC-Dor-030298	Dipodomys ordii	63.10	8.00e-105	373.00
IUUC-Ete-032493	Echinops telfairi	61.82	3.00e-171	594.00
IUUC-Eca-033962	Equus caballus	81.92	0.00e+00	766.00
IUUC-Eeu-035228	Erinaceus europaeus	71.04	1.00e-137	482.00
IUUC-Fca-036349	Felis catus	75.05	0.00e+00	724.00
IUUC-Ggo-044493	Gorilla gorilla	76.09	0.00e+00	731.00
IUUC-Hsa-046161	Homo sapiens	75.65	0.00e+00	728.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	61.18	1.00e-149	522.00
IUUC-Laf-054150	Loxodonta africana	73.64	0.00e+00	687.00
IUUC-Mcc-055076	Macaca mulatta	74.57	0.00e+00	714.00
IUUC-Mmu-063517	Mus musculus	55.08	1.00e-143	502.00
IUUC-Mpu-065752	Mustela putorius furo	76.09	0.00e+00	736.00
IUUC-Mlu-067758	Myotis lucifugus	58.74	8.00e-148	517.00
IUUC-Nle-069117	Nomascus leucogenys	76.03	0.00e+00	727.00
IUUC-Opr-071144	Ochotona princeps	67.17	1.00e-178	619.00
IUUC-Ocu-074825	Oryctolagus cuniculus	70.65	0.00e+00	678.00
IUUC-Oga-088744	Otolemur garnettii	72.41	2.00e-123	435.00
IUUC-Ptr-090519	Pan troglodytes	75.87	0.00e+00	729.00
IUUC-Pan-092059	Papio anubis	74.57	0.00e+00	716.00
IUUC-Pab-098747	Pongo abelii	76.52	0.00e+00	737.00
IUUC-Pca-100294	Procavia capensis	68.41	0.00e+00	657.00
IUUC-Pva-102129	Pteropus vampyrus	68.41	0.00e+00	663.00
IUUC-Sar-113760	Sorex araneus	65.66	1.00e-165	576.00
IUUC-Tsy-119422	Tarsius syrichta	71.15	0.00e+00	662.00
IUUC-Tbe-127628	Tupaia belangeri	60.92	2.00e-98	351.00
IUUC-Ttr-129039	Tursiops truncatus	88.02	0.00e+00	834.00
IUUC-Vpa-130188	Vicugna pacos	84.46	4.00e-147	513.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence