iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054322

UUCD1 version

UUC-LoA-00319

Ensembl Protein ID

ENSLAFP00000007836.3

UniProt Accession

G3T3K0; G3T3K0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009354.3	ENSLAFT00000009352.3	ENSLAFP00000007836.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.60e-08	34.8	20	89
E3 activity/RING/RING	6.40e-08	33.4	25	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIek.wlasggktcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC+I ++++rd v+l +G+ + r ++ + w  +   tcPv++ + ++ dl  n+tl +l+++ + e
   Q: 20   KEELLCAICYDPFRDAVTLRCGHNFCRMCVTRsWEVQVAPTCPVCKDRASPADLRTNHTLNNLVEKLLRE 89
           689***************************8736566666***********************9987765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiC+++f+d  ++l+CgH f++ C+   w     + + + +CP+C+
   Q: 25   CAICYDPFRD-AVTLRCGHNFCRMCVtRSW-----EVQVAPTCPVCK 65
           ********99.999***********98889.....799999*****6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

AAPEMEPSPA ASPGPSRSFK EELLCAICYD PFRDAVTLRC GHNFCRMCVT RSWEVQVAPT 60
CPVCKDRASP ADLRTNHTLN NLVEKLLREE AEGARWTGHR SPRLCRLHRA QFNLFCFEDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCCCCTG AGATGGAGCC GAGCCCCGCC GCGTCCCCCG GGCCTTCCCG CTCCTTCAAG 60
GAGGAGCTGC TGTGCGCGAT CTGCTACGAC CCCTTCCGCG ACGCCGTCAC TCTGCGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	90.85	0.00e+00	933.00
IUUC-Apl-003958	Anas platyrhynchos	53.44	2.00e-132	465.00
IUUC-Aca-005199	Anolis carolinensis	45.66	5.00e-123	434.00
IUUC-Ame-011964	Astyanax mexicanus	35.28	1.00e-71	263.00
IUUC-Bta-013359	Bos taurus	89.63	0.00e+00	911.00
IUUC-Cja-018900	Callithrix jacchus	76.15	0.00e+00	780.00
IUUC-Cfa-020685	Canis familiaris	90.85	0.00e+00	934.00
IUUC-Cpo-022253	Cavia porcellus	78.66	0.00e+00	779.00
IUUC-Csa-023777	Chlorocebus sabaeus	90.04	0.00e+00	931.00
IUUC-Dre-028296	Danio rerio	31.42	4.00e-69	255.00
IUUC-Dno-029065	Dasypus novemcinctus	87.65	0.00e+00	920.00
IUUC-Dor-030248	Dipodomys ordii	65.78	7.00e-102	363.00
IUUC-Ete-033183	Echinops telfairi	79.27	0.00e+00	786.00
IUUC-Eca-033263	Equus caballus	89.38	0.00e+00	808.00
IUUC-Eeu-034699	Erinaceus europaeus	78.57	5.00e-114	404.00
IUUC-Fca-036366	Felis catus	89.02	0.00e+00	919.00
IUUC-Fal-037257	Ficedula albicollis	55.95	4.00e-154	537.00
IUUC-Gmo-038512	Gadus morhua	35.15	7.00e-69	254.00
IUUC-Gga-041125	Gallus gallus	55.39	2.00e-107	382.00
IUUC-Gac-042136	Gasterosteus aculeatus	34.65	7.00e-69	254.00
IUUC-Ggo-045233	Gorilla gorilla	90.48	2.00e-172	597.00
IUUC-Hsa-046042	Homo sapiens	90.45	0.00e+00	932.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	88.01	0.00e+00	894.00
IUUC-Mcc-055555	Macaca mulatta	87.95	0.00e+00	912.00
IUUC-Meu-055900	Macropus eugenii	78.99	0.00e+00	787.00
IUUC-Mga-059380	Meleagris gallopavo	56.84	2.00e-105	375.00
IUUC-Mmr-061296	Microcebus murinus	88.41	0.00e+00	899.00
IUUC-Mdo-062811	Monodelphis domestica	78.82	0.00e+00	793.00
IUUC-Mmu-063718	Mus musculus	78.81	0.00e+00	806.00
IUUC-Mpu-066219	Mustela putorius furo	90.85	0.00e+00	918.00
IUUC-Mlu-067033	Myotis lucifugus	84.76	0.00e+00	879.00
IUUC-Nle-069806	Nomascus leucogenys	90.46	0.00e+00	874.00
IUUC-Opr-070248	Ochotona princeps	79.15	0.00e+00	773.00
IUUC-Ont-072083	Oreochromis niloticus	32.11	2.00e-69	256.00
IUUC-Oan-073364	Ornithorhynchus anatinus	68.83	7.00e-98	349.00
IUUC-Ocu-074572	Oryctolagus cuniculus	89.92	0.00e+00	943.00
IUUC-Oga-088378	Otolemur garnettii	86.79	0.00e+00	883.00
IUUC-Oar-089516	Ovis aries	88.31	0.00e+00	892.00
IUUC-Ptr-091313	Pan troglodytes	90.45	0.00e+00	932.00
IUUC-Pan-092877	Papio anubis	90.24	0.00e+00	932.00
IUUC-Psi-093928	Pelodiscus sinensis	59.79	2.00e-165	575.00
IUUC-Pab-098624	Pongo abelii	90.04	0.00e+00	926.00
IUUC-Pca-100469	Procavia capensis	88.31	0.00e+00	887.00
IUUC-Pva-103227	Pteropus vampyrus	90.04	0.00e+00	930.00
IUUC-Rno-105778	Rattus norvegicus	78.81	0.00e+00	807.00
IUUC-Sha-107392	Sarcophilus harrisii	69.01	0.00e+00	674.00
IUUC-Sar-113297	Sorex araneus	69.77	3.00e-51	194.00
IUUC-Ssc-115739	Sus scrofa	90.04	0.00e+00	904.00
IUUC-Tru-117718	Takifugu rubripes	31.98	6.00e-63	234.00
IUUC-Tbe-127926	Tupaia belangeri	86.07	6.00e-138	484.00
IUUC-Ttr-129293	Tursiops truncatus	90.85	0.00e+00	931.00
IUUC-Vpa-130379	Vicugna pacos	90.60	3.00e-161	560.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence