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Tag Content
UUCD2 ID IUUC-Sha-106965
UUCD1 version UUC-SaH-01044
Ensembl Protein ID ENSSHAP00000011256.1
UniProt Accession G3W751; G3W751_SARHA
Genbank Protein ID ENSSHAP00000011256
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AEFK01191516
Gene Name USP44
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000009686.1 ENSSHAT00000011351.1 ENSSHAP00000011256.1
ENSSHAG00000009686.1 ENSSHAT00000011352.1 ENSSHAP00000011257.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.20e-96 324.0 275 683
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...kkkeklneenp............................................ 42
           tGl+NlgNtCYmNS+LQ+Ls++  +r+++l+   ++++      +                                            
   Q: 275  TGLRNLGNTCYMNSILQVLSHLLIFRQCFLKldlNQTQ------Ellataasgktrssckhppvtdsmfhikenqekykgspglrrssl 357
           7******************************5552222......223345578888888888999999999999999999999999999 PP
   S: 43   ......................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk 109
                                 +++  +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el  
   Q: 358  ssglsggasksrsmeliqprepSSKYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKVQHEL-- 444
           999999999998888888887777777************************************************************.. PP
   S: 110  eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........slqdc 190
                  e+++++  +l  ++++k  k+  ++++++F+gql sq++cl+cdn+s++ epf+dlsl++p++ +++ +         ++++
   Q: 445  -------ETTGTRYPALIPSSQKKLIKQVLNVVNTIFHGQLLSQVTCLACDNKSNTVEPFWDLSLEFPERYHCNGKemaaqypcLVTEM 526
           .......77888888999999***********************************************9999988799999**9***** PP
   S: 191  Lesftkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
           L++ft++e leg+  y c++c+ k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c ++
   Q: 527  LAKFTETEALEGKI-YVCDQCNTKRRkfsskpvilteAQKQLMVCRLPQVLRLHLKRFRWSGR-NHREKIGVHVGFDEILNMEPYCYRE 613
           ***********965.*******999999999999999***********************997.8889********************9 PP
   S: 269  eekqke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           + k+ +  + +Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++ eev++   ++aY+lfY++
   Q: 614  SLKSLRpeCFIYDLSAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLNMCTLEEVCK---AQAYILFYTQ 683
           988776779***************************9999********************...********98 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
ILTMDKCKHV GRLRLAQDHS ILNPQKWHCV DCNTTDSVWA CLSCSHVACG RYIEEHALKH 60
FQDSNHPVAL EVNELYVFCY LCDDYVLNDN ATGDLKLLRS TLSAIKSQNY NCTTRSGRIL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-106965|DUB,USP|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTCAGATC CAAGTTATGG ACAAAAACTC ATTTGGACTA TGTATTTCTC AGCTAGACTA 60
CCTAAATATT AACAATGGAT AAATGCAAGC ATGTTGGGCG GCTTCGGCTT GCTCAAGATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-106965|DUB,USP|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:1904667--P:negative regulation of ubiquitin protein ligase activity
GO:0016579--P:protein deubiquitination
GO:0090231--P:regulation of spindle checkpoint
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 79.07 0.00e+00 1127.00
IUUC-Apl-003673 Anas platyrhynchos 84.58 0.00e+00 1136.00
IUUC-Aca-004434 Anolis carolinensis 80.82 0.00e+00 1096.00
IUUC-Ame-010986 Astyanax mexicanus 69.36 0.00e+00 910.00
IUUC-Bta-012774 Bos taurus 78.00 0.00e+00 1123.00
IUUC-Cja-019619 Callithrix jacchus 78.54 0.00e+00 1112.00
IUUC-Cfa-020957 Canis familiaris 78.23 0.00e+00 1129.00
IUUC-Csa-023177 Chlorocebus sabaeus 78.12 0.00e+00 1113.00
IUUC-Cho-024877 Choloepus hoffmanni 76.35 0.00e+00 712.00
IUUC-Csv-025814 Ciona savignyi 42.70 4.00e-150 525.00
IUUC-Dre-027878 Danio rerio 67.50 0.00e+00 873.00
IUUC-Dno-029832 Dasypus novemcinctus 79.07 0.00e+00 1127.00
IUUC-Ete-032627 Echinops telfairi 76.76 0.00e+00 1093.00
IUUC-Eca-033863 Equus caballus 75.63 0.00e+00 1061.00
IUUC-Eeu-035225 Erinaceus europaeus 74.05 0.00e+00 1037.00
IUUC-Fca-036288 Felis catus 78.37 0.00e+00 1120.00
IUUC-Fal-037207 Ficedula albicollis 82.13 0.00e+00 1103.00
IUUC-Gga-040457 Gallus gallus 83.79 0.00e+00 1088.00
IUUC-Ggo-044926 Gorilla gorilla 78.17 0.00e+00 1109.00
IUUC-Hsa-046079 Homo sapiens 78.12 0.00e+00 1107.00
IUUC-Itr-048737 Ictidomys tridecemlineatus 78.55 0.00e+00 1099.00
IUUC-Lch-050260 Latimeria chalumnae 74.19 0.00e+00 985.00
IUUC-Loc-051981 Lepisosteus oculatus 79.49 0.00e+00 692.00
IUUC-Laf-054491 Loxodonta africana 78.59 0.00e+00 1073.00
IUUC-Mcc-055694 Macaca mulatta 78.03 0.00e+00 1112.00
IUUC-Mga-059523 Meleagris gallopavo 83.43 0.00e+00 1110.00
IUUC-Mmr-060885 Microcebus murinus 80.22 0.00e+00 1139.00
IUUC-Mdo-063018 Monodelphis domestica 95.23 0.00e+00 1319.00
IUUC-Mmu-064012 Mus musculus 70.52 0.00e+00 947.00
IUUC-Mpu-066207 Mustela putorius furo 78.65 0.00e+00 1134.00
IUUC-Mlu-066929 Myotis lucifugus 76.45 0.00e+00 1057.00
IUUC-Nle-069313 Nomascus leucogenys 69.35 0.00e+00 945.00
IUUC-Opr-070375 Ochotona princeps 74.33 0.00e+00 1018.00
IUUC-Ont-071637 Oreochromis niloticus 69.34 0.00e+00 909.00
IUUC-Oan-073030 Ornithorhynchus anatinus 87.78 0.00e+00 952.00
IUUC-Ocu-074836 Oryctolagus cuniculus 76.68 0.00e+00 1055.00
IUUC-Oga-088367 Otolemur garnettii 79.58 0.00e+00 1110.00
IUUC-Oar-089953 Ovis aries 78.14 0.00e+00 1131.00
IUUC-Ptr-090980 Pan troglodytes 78.12 0.00e+00 1107.00
IUUC-Pan-092748 Papio anubis 78.51 0.00e+00 1122.00
IUUC-Psi-094078 Pelodiscus sinensis 85.96 0.00e+00 941.00
IUUC-Pab-098514 Pongo abelii 78.87 0.00e+00 1117.00
IUUC-Pva-102984 Pteropus vampyrus 78.66 0.00e+00 1112.00
IUUC-Rno-106019 Rattus norvegicus 70.59 0.00e+00 992.00
IUUC-Ssc-115299 Sus scrofa 78.70 0.00e+00 1141.00
IUUC-Tgu-117160 Taeniopygia guttata 82.02 0.00e+00 1099.00
IUUC-Tru-118156 Takifugu rubripes 67.52 0.00e+00 889.00
IUUC-Tni-119733 Tetraodon nigroviridis 66.05 0.00e+00 884.00
IUUC-Tbe-128084 Tupaia belangeri 75.04 0.00e+00 1049.00
IUUC-Ttr-128928 Tursiops truncatus 79.13 0.00e+00 1147.00
IUUC-Vpa-130706 Vicugna pacos 79.07 0.00e+00 1131.00
Created Date 25-Jun-2017

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