iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009463

Ensembl Protein ID

CADANIAP00000685

UniProt Accession

C8VBR5; C8VBR5_EMENI

Genbank Protein ID

CBF79663.1

Protein Name

Ubiquitin conjugating enzyme, putative (AFU_orthologue AFUA_2G15040)

Genbank Nucleotide ID

BN001304

Gene Name

ANIA_07577

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00000685	CADANIAT00000685	CADANIAP00000685

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.10e-46	155.0	8	156

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}
381	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyenGkvClsilk. 87
           R+++e+k++e++   +i ++ +++ d+ + +++ilGp++tpY+ g+F+++i+f +dYP+++P+v+ lt+     +f+Pn+y+ GkvClsil+ 
   Q: 8    RITREIKQIENSADLSIAVDYDEK-DIRNVRAVILGPPETPYQFGFFEFSIKFGKDYPARAPSVRALTTnsgvcRFSPNLYAGGKVCLSILGt 99
           89******************9999.9*****************************************999*********************66 PP
   S: 88   ....eeekWspalsvesvllsiqsll.aepnpesplneeaaellkknre.eykkkvr 138
               + e+Ws+a+ +esvl+siqsl+ ++p+ ++p +e+a +++ +++  +yk k+r
   Q: 100  wtgqPGEQWSSAQGLESVLISIQSLMsSNPYENEPGYEHAKSQTDEENMaHYKAKIR 156
           667799********************777***********98887665538998886 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MSDQAIIRIT REIKQIENSA DLSIAVDYDE KDIRNVRAVI LGPPETPYQF GFFEFSIKFG 60
KDYPARAPSV RALTTNSGVC RFSPNLYAGG KVCLSILGTW TGQPGEQWSS AQGLESVLIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCATCATA GCCTTTTGGA TCTCTCATCC TAACAGGAAC ATATCCTCCT CTCGGAACTT 60
TACGCCGTCC TCTCGATCTC AGGCTATCAG ACAGTCTGGT CTCACGTCGG ATCAATATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001560	Ailuropoda melanoleuca	36.36	7.00e-34	135.00
IUUC-Apl-003980	Anas platyrhynchos	36.16	4.00e-33	133.00
IUUC-Aca-005372	Anolis carolinensis	36.73	2.00e-34	138.00
IUUC-Acl-008373	Aspergillus clavatus	60.47	6.00e-142	495.00
IUUC-Afl-008391	Aspergillus flavus	62.98	2.00e-125	440.00
IUUC-Afu-009108	Aspergillus fumigatus	56.75	1.00e-142	498.00
IUUC-Ang-009532	Aspergillus niger	60.52	9.00e-129	451.00
IUUC-Ate-010525	Aspergillus terreus	56.12	3.00e-145	506.00
IUUC-Ame-011940	Astyanax mexicanus	47.95	7.00e-34	136.00
IUUC-Bta-012643	Bos taurus	36.96	7.00e-36	142.00
IUUC-Bci-013596	Botrytis cinerea	53.90	8.00e-137	478.00
IUUC-Cel-018661	Caenorhabditis elegans	43.45	5.00e-33	134.00
IUUC-Cja-018722	Callithrix jacchus	36.07	2.00e-34	138.00
IUUC-Cfa-020605	Canis familiaris	36.73	3.00e-34	136.00
IUUC-Cpo-021673	Cavia porcellus	36.90	1.00e-33	135.00
IUUC-Csa-024068	Chlorocebus sabaeus	36.79	4.00e-36	143.00
IUUC-Cho-024890	Choloepus hoffmanni	40.46	4.00e-22	100.00
IUUC-Cgl-026412	Colletotrichum gloeosporioides	51.11	8.00e-130	455.00
IUUC-Cne-026995	Cryptococcus neoformans	31.88	7.00e-20	90.90
IUUC-Dre-027988	Danio rerio	48.52	9.00e-34	135.00
IUUC-Dno-029140	Dasypus novemcinctus	35.82	5.00e-34	136.00
IUUC-Dor-030106	Dipodomys ordii	48.10	3.00e-31	126.00
IUUC-Dse-031321	Dothistroma septosporum	46.53	4.00e-111	393.00
IUUC-Dme-031592	Drosophila melanogaster	40.54	1.00e-24	109.00
IUUC-Ete-032587	Echinops telfairi	36.99	6.00e-22	100.00
IUUC-Eca-034348	Equus caballus	36.33	2.00e-34	137.00
IUUC-Eeu-034803	Erinaceus europaeus	37.50	6.00e-31	125.00
IUUC-Fca-036527	Felis catus	35.97	4.00e-34	136.00
IUUC-Fal-037318	Ficedula albicollis	38.36	3.00e-23	104.00
IUUC-Fox-037961	Fusarium oxysporum	53.56	4.00e-133	466.00
IUUC-Fso-038352	Fusarium solani	50.33	5.00e-119	419.00
IUUC-Gmo-038800	Gadus morhua	46.78	5.00e-33	133.00
IUUC-Ggr-040018	Gaeumannomyces graminis	54.34	1.00e-124	437.00
IUUC-Gga-041237	Gallus gallus	36.73	1.00e-34	138.00
IUUC-Gac-041848	Gasterosteus aculeatus	47.95	3.00e-34	137.00
IUUC-Ggo-045631	Gorilla gorilla	27.50	6.00e-23	99.00
IUUC-Hsa-046207	Homo sapiens	36.79	4.00e-36	143.00
IUUC-Itr-048609	Ictidomys tridecemlineatus	36.33	2.00e-34	137.00
IUUC-Lch-050278	Latimeria chalumnae	47.93	5.00e-34	136.00
IUUC-Loc-052800	Lepisosteus oculatus	38.67	7.00e-24	106.00
IUUC-Lma-053044	Leptosphaeria maculans	53.79	3.00e-137	479.00
IUUC-Laf-053726	Loxodonta africana	36.46	8.00e-33	132.00
IUUC-Mcc-055267	Macaca mulatta	38.36	1.00e-23	105.00
IUUC-Meu-056221	Macropus eugenii	50.00	5.00e-25	105.00
IUUC-Mor-057074	Magnaporthe oryzae	53.88	5.00e-120	422.00
IUUC-Mpo-057495	Magnaporthe poae	54.57	2.00e-125	441.00
IUUC-Mga-060059	Meleagris gallopavo	36.03	3.00e-33	133.00
IUUC-Mmr-061455	Microcebus murinus	37.05	9.00e-35	139.00
IUUC-Mdo-062002	Monodelphis domestica	37.22	6.00e-33	132.00
IUUC-Mmu-063224	Mus musculus	36.79	4.00e-36	143.00
IUUC-Mpu-066230	Mustela putorius furo	36.07	1.00e-34	137.00
IUUC-Mlu-067587	Myotis lucifugus	36.63	9.00e-34	135.00
IUUC-Nfi-068281	Neosartorya fischeri	61.56	2.00e-142	497.00
IUUC-Ncr-068852	Neurospora crassa	53.32	6.00e-123	432.00
IUUC-Nle-069355	Nomascus leucogenys	33.45	7.00e-29	119.00
IUUC-Opr-070799	Ochotona princeps	38.36	2.00e-23	105.00
IUUC-Ont-071793	Oreochromis niloticus	48.52	6.00e-34	136.00
IUUC-Oan-073328	Ornithorhynchus anatinus	52.11	1.00e-31	127.00
IUUC-Ocu-073819	Oryctolagus cuniculus	36.88	5.00e-36	143.00
IUUC-Ola-087432	Oryzias latipes	35.45	3.00e-33	133.00
IUUC-Oga-087941	Otolemur garnettii	36.79	4.00e-36	143.00
IUUC-Oar-089782	Ovis aries	35.97	4.00e-34	136.00
IUUC-Ptr-091361	Pan troglodytes	36.79	5.00e-36	143.00
IUUC-Pan-092426	Papio anubis	36.79	3.00e-36	144.00
IUUC-Pma-094305	Petromyzon marinus	52.59	1.00e-27	114.00
IUUC-Pno-094902	Phaeosphaeria nodorum	49.21	2.00e-109	387.00
IUUC-Ppa-095592	Physcomitrella patens	48.41	1.00e-31	130.00
IUUC-Pfo-097059	Poecilia formosa	46.78	5.00e-38	150.00
IUUC-Pab-097711	Pongo abelii	47.56	4.00e-31	125.00
IUUC-Pca-100473	Procavia capensis	36.40	1.00e-33	134.00
IUUC-Pva-103012	Pteropus vampyrus	36.79	4.00e-36	143.00
IUUC-Pte-104107	Pyrenophora teres	53.14	2.00e-135	473.00
IUUC-Pyt-104452	Pyrenophora triticirepentis	53.36	5.00e-136	475.00
IUUC-Rno-105444	Rattus norvegicus	36.79	4.00e-36	143.00
IUUC-Sha-107291	Sarcophilus harrisii	37.22	7.00e-33	132.00
IUUC-Smo-109135	Selaginella moellendorffii	42.47	4.00e-24	103.00
IUUC-Sar-113102	Sorex araneus	53.57	2.00e-24	104.00
IUUC-Ssc-115575	Sus scrofa	36.79	3.00e-36	143.00
IUUC-Tgu-117132	Taeniopygia guttata	38.10	6.00e-23	103.00
IUUC-Tru-117883	Takifugu rubripes	48.52	7.00e-34	136.00
IUUC-Tsy-118899	Tarsius syrichta	38.89	2.00e-23	105.00
IUUC-Tni-120523	Tetraodon nigroviridis	47.40	4.00e-34	137.00
IUUC-Tre-121946	Trichoderma reesei	49.44	3.00e-125	440.00
IUUC-Tvi-122513	Trichoderma virens	50.44	9.00e-128	448.00
IUUC-Tme-126888	Tuber melanosporum	53.45	3.00e-135	473.00
IUUC-Ttr-128772	Tursiops truncatus	36.40	1.00e-33	134.00
IUUC-Vda-129728	Verticillium dahliae	50.22	1.00e-116	411.00
IUUC-Vpa-130763	Vicugna pacos	54.13	1.00e-23	100.00
IUUC-Xtr-132764	Xenopus tropicalis	49.11	3.00e-35	140.00
IUUC-Xma-134051	Xiphophorus maculatus	48.52	5.00e-34	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence