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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063132
UUCD1 version UUC-MuM-00473
Ensembl Protein ID ENSMUSP00000024206.5
UniProt Accession Q61011; GBB3_MOUSE
Genbank Protein ID AAC36013.1; BAB29553.1; AAH18239.1; AAB01725.1
Protein Name Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Transducin beta chain 3
Genbank Nucleotide ID AC002397; AK014789; BC018239; U38494
Gene Name Gnb3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000023439.11 ENSMUST00000024206.5 ENSMUSP00000024206.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.50e-38 130.2 53 88
UBD/Beta-Prp 4.00e-52 178.4 46 267
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH ++++++++ +d +llvs+s Dg++ vWD+ t +
   Q: 53   GHLAKIYAMHWaTDsKLLVSASQDGKLIVWDTYTTN 88
           899*********888****************87765 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+k+lv++s+D+ + vwd  t   vh++   ++ v+++++ psg++++ G+ d++  +++l++++   +
   Q: 46   RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVK 134
           45689*****************************************************************************9987777 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               ls h+g  +c ++ + +n +v++s D+t+ lWd++tg+  + + g ht++  sl+++++ k ++sg++d + klwd+++g+c +t
   Q: 135  vsrELSAHTGYLSCCRFLD-DNNIVTSSGDTTCALWDIETGQQKTVFVG-HTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQT 221
           778***************9.566899**********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           ++gh++ ++ + f+pn+e + +gs+D s r++dlr ++ l++++++
   Q: 222  FTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQE 267
           **************************************99999883 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2 (By similarity).
 G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2 (By similarity).
Protein Sequence
(Fasta)
MGEMEQLRQE AEQLKKQIAD ARKACADITL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA 60
MHWATDSKLL VSASQDGKLI VWDTYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063132|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GACCGTGGAA GCACCCCTCT ATCCCCACCC CCCTTCTTGT GGCTGCATAA GAGGGGTGCT 60
GCTCTTCTCT GGTCCACGGG CCTGTTTCCC ACCCCTCCAG GCTGACCTGT CTCTGGAAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063132|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0044297--C:cell body
GO:0030425--C:dendrite
GO:0070062--C:extracellular exosome
GO:0005834--C:heterotrimeric G-protein complex
GO:0003924--F:GTPase activity
GO:0051020--F:GTPase binding
GO:0004871--F:signal transducer activity
GO:0030507--F:spectrin binding
GO:0007186--P:G-protein coupled receptor signaling pathway
KEGG mmu:14695
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000161 Aegilops tauschii 50.00 4.00e-76 278.00
IUUC-Aml-002370 Ailuropoda melanoleuca 98.24 0.00e+00 694.00
IUUC-Atr-002610 Amborella trichopoda 49.35 7.00e-88 317.00
IUUC-Apl-004079 Anas platyrhynchos 93.53 0.00e+00 673.00
IUUC-Aca-004539 Anolis carolinensis 90.00 0.00e+00 650.00
IUUC-Aly-006025 Arabidopsis lyrata 50.32 1.00e-83 303.00
IUUC-Ath-006617 Arabidopsis thaliana 50.32 2.00e-83 302.00
IUUC-Bgr-012079 Blumeria graminis 65.38 3.00e-132 464.00
IUUC-Bta-012810 Bos taurus 97.65 0.00e+00 691.00
IUUC-Bci-013621 Botrytis cinerea 66.37 2.00e-131 461.00
IUUC-Bdi-014785 Brachypodium distachyon 50.00 2.00e-87 315.00
IUUC-Bol-015759 Brassica oleracea 50.96 1.00e-81 298.00
IUUC-Bra-016695 Brassica rapa 51.45 1.00e-81 296.00
IUUC-Cja-019894 Callithrix jacchus 96.76 0.00e+00 685.00
IUUC-Cfa-020140 Canis familiaris 97.94 0.00e+00 692.00
IUUC-Cpo-021908 Cavia porcellus 98.24 0.00e+00 695.00
IUUC-Csa-023321 Chlorocebus sabaeus 97.06 0.00e+00 686.00
IUUC-Dno-029783 Dasypus novemcinctus 96.46 0.00e+00 628.00
IUUC-Dse-031388 Dothistroma septosporum 67.26 3.00e-138 484.00
IUUC-Ete-032435 Echinops telfairi 90.00 2.00e-178 618.00
IUUC-Eca-034169 Equus caballus 98.53 0.00e+00 695.00
IUUC-Eeu-034631 Erinaceus europaeus 91.56 2.00e-165 574.00
IUUC-Fca-035392 Felis catus 97.65 0.00e+00 691.00
IUUC-Fal-036902 Ficedula albicollis 91.47 0.00e+00 663.00
IUUC-Gga-040655 Gallus gallus 92.08 0.00e+00 657.00
IUUC-Gma-043322 Glycine max 44.54 9.00e-88 317.00
IUUC-Ggo-045346 Gorilla gorilla 97.06 0.00e+00 686.00
IUUC-Hsa-046203 Homo sapiens 97.06 0.00e+00 686.00
IUUC-Hvu-047596 Hordeum vulgare 50.00 3.00e-86 311.00
IUUC-Itr-048501 Ictidomys tridecemlineatus 97.94 0.00e+00 692.00
IUUC-Lpe-051040 Leersia perrieri 49.68 5.00e-88 317.00
IUUC-Loc-052327 Lepisosteus oculatus 86.76 0.00e+00 634.00
IUUC-Laf-053616 Loxodonta africana 97.35 0.00e+00 691.00
IUUC-Mcc-055798 Macaca mulatta 97.06 0.00e+00 686.00
IUUC-Mtr-058752 Medicago truncatula 48.87 7.00e-87 314.00
IUUC-Mga-059516 Meleagris gallopavo 93.53 0.00e+00 672.00
IUUC-Mmr-061701 Microcebus murinus 98.24 0.00e+00 692.00
IUUC-Mdo-061879 Monodelphis domestica 93.53 0.00e+00 667.00
IUUC-Mac-064871 Musa acuminata 49.68 2.00e-85 309.00
IUUC-Mpu-066365 Mustela putorius furo 97.65 0.00e+00 694.00
IUUC-Mlu-067628 Myotis lucifugus 96.47 0.00e+00 682.00
IUUC-Nle-069015 Nomascus leucogenys 95.59 0.00e+00 669.00
IUUC-Opr-070261 Ochotona princeps 98.53 0.00e+00 696.00
IUUC-Ocu-074255 Oryctolagus cuniculus 98.82 0.00e+00 697.00
IUUC-Oba-075818 Oryza barthii 48.00 7.00e-85 307.00
IUUC-Obr-076229 Oryza brachyantha 49.36 4.00e-85 308.00
IUUC-Ogl-077730 Oryza glaberrima 50.00 3.00e-88 318.00
IUUC-Ogu-078583 Oryza glumaepatula 49.62 6.00e-70 257.00
IUUC-Oin-079661 Oryza indica 49.36 5.00e-85 307.00
IUUC-Olo-080225 Oryza longistaminata 49.62 6.00e-70 257.00
IUUC-Oni-082161 Oryza nivara 49.68 7.00e-88 317.00
IUUC-Opu-084072 Oryza punctata 50.00 3.00e-88 318.00
IUUC-Oru-084316 Oryza rufipogon 49.36 5.00e-85 307.00
IUUC-Osa-085380 Oryza sativa 49.36 5.00e-85 307.00
IUUC-Oga-088685 Otolemur garnettii 98.53 0.00e+00 696.00
IUUC-Oar-089373 Ovis aries 94.43 0.00e+00 655.00
IUUC-Ptr-090627 Pan troglodytes 94.41 0.00e+00 665.00
IUUC-Pan-092347 Papio anubis 97.05 0.00e+00 684.00
IUUC-Psi-092965 Pelodiscus sinensis 93.53 0.00e+00 672.00
IUUC-Pno-095135 Phaeosphaeria nodorum 65.78 9.00e-137 479.00
IUUC-Ppa-095726 Physcomitrella patens 45.86 8.00e-76 277.00
IUUC-Pab-098335 Pongo abelii 96.47 0.00e+00 683.00
IUUC-Pop-099273 Populus trichocarpa 50.32 4.00e-88 318.00
IUUC-Ppe-102016 Prunus persica 48.71 4.00e-86 311.00
IUUC-Pva-102666 Pteropus vampyrus 98.53 0.00e+00 693.00
IUUC-Pte-104053 Pyrenophora teres 65.78 6.00e-137 480.00
IUUC-Rno-105834 Rattus norvegicus 98.82 0.00e+00 662.00
IUUC-Sha-107128 Sarcophilus harrisii 94.12 0.00e+00 667.00
IUUC-Spo-108352 Schizosaccharomyces pombe 43.33 6.00e-69 254.00
IUUC-Ssl-108539 Sclerotinia sclerotiorum 66.57 4.00e-131 461.00
IUUC-Smo-109652 Selaginella moellendorffii 44.17 2.00e-74 272.00
IUUC-Sit-110441 Setaria italica 49.68 8.00e-88 317.00
IUUC-Sly-111784 Solanum lycopersicum 50.32 2.00e-86 312.00
IUUC-Stu-112400 Solanum tuberosum 50.32 2.00e-86 312.00
IUUC-Sbi-114038 Sorghum bicolor 49.04 2.00e-86 312.00
IUUC-Ssc-115886 Sus scrofa 97.94 0.00e+00 692.00
IUUC-Tgu-116461 Taeniopygia guttata 92.06 0.00e+00 666.00
IUUC-Tca-121224 Theobroma cacao 50.65 8.00e-89 320.00
IUUC-Tae-125653 Triticum aestivum 50.32 2.00e-86 312.00
IUUC-Tur-126755 Triticum urartu 49.84 5.00e-87 316.00
IUUC-Tbe-127694 Tupaia belangeri 80.88 2.00e-148 518.00
IUUC-Vvi-131162 Vitis vinifera 50.65 2.00e-88 318.00
IUUC-Xtr-132928 Xenopus tropicalis 88.82 6.00e-180 623.00
IUUC-Yli-134396 Yarrowia lipolytica 31.65 1.00e-61 229.00
IUUC-Zma-135893 Zea mays 49.04 2.00e-86 312.00
Created Date 25-Jun-2017

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