iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069517

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01031745

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000001031.2	ENSNLET00000001317.2	ENSNLEP00000001242.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.80e-25	88.2	404	475
E3 adaptor/Cullin RING/DCX/DWD	4.90e-40	133.8	11	44
UBD/Beta-Prp	2.90e-53	180.9	7	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+ef+CpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFICPITRELMKDPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLPSAVLTPNRTLKMAINRWLETHQ 475
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H d+v+c+af  s  ll+++s D+ti++++lr+++ 
   Q: 11   HGDDVNCCAFsfS--LLATCSLDKTIRLYSLRDFTE 44
           9*********644..9***************99875 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  + sllat s d+ti+++++++ +    + l+ h+ +v +++fsp+g il+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SFSLLATCSLDKTIRLYSLRDFTElpHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVM 92
           566666655.55889..9*******************9666667889****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  l+sG +d t+ +w+ ++++ ++ + s++dg+    +++p+g+ +v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYR-CGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           9765267*********************************9.**********************************8.5678888877. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+           ++l+s+++d +vk+w ++
   Q: 179  HDLGITCCDFSSQPvsdgeqglqfFRLASCGQDCQVKIWIVS 220
           *********9998899999********************765 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAKLINTLAD HGDDVNCCAF SFSLLATCSL DKTIRLYSLR DFTELPHSPL KFHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTENGQMLA VMEQPSGSPV RVCQFSPDST CLASGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCTGTTC CCCCTGCACT GGGTCTCCGC TGGCGCCCGC CCCGCCCGCC TCACCTGCGC 60
GGCACGTGAT CCGCACCGCC TGTGGGCACC TGAAGGCGGA TCACGCGCGT CCCGGGTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

nle:100597443

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000612	Aegilops tauschii	53.03	3.00e-17	83.60
IUUC-Aml-001614	Ailuropoda melanoleuca	93.28	0.00e+00	932.00
IUUC-Apl-003529	Anas platyrhynchos	75.84	0.00e+00	759.00
IUUC-Aca-004257	Anolis carolinensis	70.43	0.00e+00	700.00
IUUC-Ame-011357	Astyanax mexicanus	51.36	1.00e-115	409.00
IUUC-Bta-013032	Bos taurus	87.84	0.00e+00	878.00
IUUC-Cja-018743	Callithrix jacchus	95.59	0.00e+00	946.00
IUUC-Cfa-021197	Canis familiaris	91.81	0.00e+00	923.00
IUUC-Cpo-022279	Cavia porcellus	90.55	0.00e+00	905.00
IUUC-Csa-023954	Chlorocebus sabaeus	97.69	0.00e+00	961.00
IUUC-Cho-025083	Choloepus hoffmanni	74.87	2.00e-160	557.00
IUUC-Cin-025786	Ciona intestinalis	34.68	4.00e-79	288.00
IUUC-Dre-028087	Danio rerio	56.58	2.00e-143	501.00
IUUC-Dno-028919	Dasypus novemcinctus	93.07	0.00e+00	927.00
IUUC-Dor-031112	Dipodomys ordii	89.92	0.00e+00	892.00
IUUC-Ete-032405	Echinops telfairi	90.67	0.00e+00	649.00
IUUC-Eca-033254	Equus caballus	90.13	0.00e+00	899.00
IUUC-Eeu-034545	Erinaceus europaeus	86.55	0.00e+00	836.00
IUUC-Fca-035482	Felis catus	93.07	0.00e+00	928.00
IUUC-Fal-036976	Ficedula albicollis	63.15	8.00e-167	579.00
IUUC-Gmo-039213	Gadus morhua	54.62	5.00e-137	480.00
IUUC-Gga-040561	Gallus gallus	74.42	0.00e+00	746.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.77	2.00e-141	495.00
IUUC-Ggo-045503	Gorilla gorilla	98.95	0.00e+00	977.00
IUUC-Hsa-045910	Homo sapiens	98.95	0.00e+00	977.00
IUUC-Hvu-047757	Hordeum vulgare	43.96	1.00e-18	88.20
IUUC-Itr-048214	Ictidomys tridecemlineatus	91.51	0.00e+00	719.00
IUUC-Loc-052307	Lepisosteus oculatus	59.13	1.00e-165	576.00
IUUC-Laf-053587	Loxodonta africana	92.23	0.00e+00	918.00
IUUC-Mcc-055679	Macaca mulatta	98.11	0.00e+00	971.00
IUUC-Meu-055962	Macropus eugenii	71.64	0.00e+00	659.00
IUUC-Mga-059652	Meleagris gallopavo	74.00	0.00e+00	749.00
IUUC-Mmr-060943	Microcebus murinus	91.21	0.00e+00	904.00
IUUC-Mdo-062592	Monodelphis domestica	82.67	0.00e+00	829.00
IUUC-Mmu-063577	Mus musculus	82.14	0.00e+00	816.00
IUUC-Mpu-066422	Mustela putorius furo	91.81	0.00e+00	917.00
IUUC-Mlu-067250	Myotis lucifugus	91.18	0.00e+00	905.00
IUUC-Opr-070776	Ochotona princeps	90.97	0.00e+00	891.00
IUUC-Ont-071821	Oreochromis niloticus	57.32	5.00e-150	524.00
IUUC-Oan-073706	Ornithorhynchus anatinus	82.74	0.00e+00	829.00
IUUC-Ocu-074766	Oryctolagus cuniculus	84.17	0.00e+00	812.00
IUUC-Ola-086531	Oryzias latipes	57.05	6.00e-146	510.00
IUUC-Oga-088388	Otolemur garnettii	90.97	0.00e+00	908.00
IUUC-Oar-089748	Ovis aries	88.47	0.00e+00	879.00
IUUC-Ptr-090616	Pan troglodytes	98.94	0.00e+00	971.00
IUUC-Pan-091769	Papio anubis	98.26	0.00e+00	697.00
IUUC-Psi-093334	Pelodiscus sinensis	78.36	0.00e+00	737.00
IUUC-Pma-094383	Petromyzon marinus	48.33	4.00e-132	464.00
IUUC-Pfo-096801	Poecilia formosa	55.74	2.00e-146	511.00
IUUC-Pab-098139	Pongo abelii	98.20	0.00e+00	789.00
IUUC-Pca-100523	Procavia capensis	76.68	0.00e+00	737.00
IUUC-Pva-102286	Pteropus vampyrus	90.76	0.00e+00	880.00
IUUC-Rno-104831	Rattus norvegicus	83.82	0.00e+00	837.00
IUUC-Sha-107499	Sarcophilus harrisii	84.03	0.00e+00	843.00
IUUC-Sar-113389	Sorex araneus	87.18	0.00e+00	848.00
IUUC-Tgu-116769	Taeniopygia guttata	73.11	0.00e+00	729.00
IUUC-Tru-118774	Takifugu rubripes	53.09	2.00e-139	488.00
IUUC-Tsy-119595	Tarsius syrichta	81.80	0.00e+00	660.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.99	2.00e-147	515.00
IUUC-Tur-126683	Triticum urartu	51.52	5.00e-17	83.20
IUUC-Tbe-127938	Tupaia belangeri	83.28	3.00e-148	517.00
IUUC-Ttr-128193	Tursiops truncatus	90.80	0.00e+00	771.00
IUUC-Vpa-130275	Vicugna pacos	92.02	0.00e+00	914.00
IUUC-Xtr-131982	Xenopus tropicalis	61.68	2.00e-171	595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence