iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003839

Ensembl Protein ID

ENSAPLP00000011190.1

UniProt Accession

R0JB33; R0JB33_ANAPL

Genbank Protein ID

EOA94435.1

Protein Name

Suppressor of cytokine signaling 4

Genbank Nucleotide ID

ADON01134789

Gene Name

SOCS4; Anapl_11814

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011447.1	ENSAPLT00000011913.1	ENSAPLP00000011190.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	9.70e-16	57.1	374	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l r+ p+SLqh+CR +I++c++++++   d+LP+P+s k YL++++y+
   Q: 374  STPLNRTFPFSLQHICRTVICNCTTYDGI---DALPIPPSVKLYLKEYHYK 421
           5678899**********************...****************985 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MADNKDSNVK NADVRPKSSR SRSADRKDGY VWSGKKLSWS KKSEHCSDAE TASAVGRSGS 60
NLKSQERKYS CSSIELDLDR SCGHRFLGRS LKQKLQDAVG QCFPIKNCSS RHASGLQSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGACA ATAAGGACAG TAACGTTAAA AACGCAGATG TCAGACCCAA AAGCAGCCGG 60
AGCAGAAGCG CGGACAGAAA GGATGGTTAC GTGTGGAGCG GGAAGAAGCT CTCCTGGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

KEGG

apla:101804231

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	80.82	0.00e+00	676.00
IUUC-Aca-004840	Anolis carolinensis	80.46	0.00e+00	719.00
IUUC-Bta-012503	Bos taurus	81.09	0.00e+00	678.00
IUUC-Bol-016597	Brassica oleracea	30.38	2.20e-02	33.90
IUUC-Cja-019284	Callithrix jacchus	79.50	0.00e+00	670.00
IUUC-Cfa-020890	Canis familiaris	80.64	0.00e+00	679.00
IUUC-Cpo-022081	Cavia porcellus	72.73	0.00e+00	634.00
IUUC-Csa-023076	Chlorocebus sabaeus	79.50	0.00e+00	674.00
IUUC-Cho-024700	Choloepus hoffmanni	78.64	0.00e+00	697.00
IUUC-Dno-029961	Dasypus novemcinctus	79.09	0.00e+00	701.00
IUUC-Dor-030273	Dipodomys ordii	80.91	0.00e+00	678.00
IUUC-Ete-032972	Echinops telfairi	80.06	2.00e-148	517.00
IUUC-Eca-034289	Equus caballus	79.77	0.00e+00	674.00
IUUC-Eeu-035208	Erinaceus europaeus	79.72	0.00e+00	660.00
IUUC-Fal-036829	Ficedula albicollis	92.66	0.00e+00	737.00
IUUC-Gga-040725	Gallus gallus	92.43	0.00e+00	779.00
IUUC-Ggo-044886	Gorilla gorilla	79.27	0.00e+00	670.00
IUUC-Hsa-046322	Homo sapiens	79.04	0.00e+00	669.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	80.60	0.00e+00	663.00
IUUC-Lch-049459	Latimeria chalumnae	58.49	1.00e-144	505.00
IUUC-Laf-053484	Loxodonta africana	80.23	0.00e+00	668.00
IUUC-Mcc-054890	Macaca mulatta	79.27	0.00e+00	673.00
IUUC-Meu-056532	Macropus eugenii	76.71	1.00e-170	592.00
IUUC-Mvi-060418	Microbotryum violaceum	32.10	6.10e-02	30.40
IUUC-Mmr-061714	Microcebus murinus	79.73	0.00e+00	671.00
IUUC-Mmu-063161	Mus musculus	76.13	0.00e+00	631.00
IUUC-Mpu-066499	Mustela putorius furo	79.32	0.00e+00	698.00
IUUC-Mlu-066945	Myotis lucifugus	78.64	0.00e+00	655.00
IUUC-Nle-069976	Nomascus leucogenys	79.04	0.00e+00	667.00
IUUC-Opr-070255	Ochotona princeps	77.68	0.00e+00	656.00
IUUC-Ocu-074764	Oryctolagus cuniculus	80.00	0.00e+00	673.00
IUUC-Oga-088910	Otolemur garnettii	77.73	0.00e+00	682.00
IUUC-Oar-090330	Ovis aries	81.09	0.00e+00	679.00
IUUC-Ptr-090709	Pan troglodytes	79.27	0.00e+00	670.00
IUUC-Pan-092540	Papio anubis	79.50	0.00e+00	674.00
IUUC-Psi-093678	Pelodiscus sinensis	86.47	0.00e+00	793.00
IUUC-Pfo-097139	Poecilia formosa	80.92	6.00e-88	317.00
IUUC-Pab-097970	Pongo abelii	76.41	2.00e-154	537.00
IUUC-Pca-100211	Procavia capensis	69.77	1.00e-160	559.00
IUUC-Rno-106014	Rattus norvegicus	73.80	0.00e+00	630.00
IUUC-Sha-106822	Sarcophilus harrisii	77.68	0.00e+00	672.00
IUUC-Ssc-115821	Sus scrofa	80.00	0.00e+00	674.00
IUUC-Tgu-117117	Taeniopygia guttata	93.35	0.00e+00	741.00
IUUC-Tsy-118979	Tarsius syrichta	95.10	6.00e-119	419.00
IUUC-Tca-121131	Theobroma cacao	30.77	5.00e-03	35.00
IUUC-Vpa-130626	Vicugna pacos	80.68	0.00e+00	686.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence