iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013238

Ensembl Protein ID

ENSBTAP00000001047.4

UniProt Accession

A5PKG7; KCTD5_BOVIN

Genbank Protein ID

AAI42482.1

Protein Name

BTB/POZ domain-containing protein KCTD5

Genbank Nucleotide ID

BC142481

Gene Name

KCTD5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000040575.1	ENSBTAT00000001047.4	ENSBTAP00000001047.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.90e-11	43.7	44	114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaas.SsvFyalf..lmele.esksklmveikdvqpevfrallkFlYtgklden 68
           ++v l+vgg++f +++ +L++   s++y+l+  + +l+ ++++++ + i+ ++p++f  +l++l++gkl +n
   Q: 44   KWVRLNVGGTYFLTTRQTLCRDpKSFLYRLCqaDPDLDsDKDETGAYLID-RDPTYFGPVLNYLRHGKLVIN 114
           59*****************************7777777788999999**9.******************887 PP

Organism

Bos taurus

Functional Description
(View)

Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity).

Protein Sequence
(Fasta)

MAENHCELLP PAPGGLGAGL GGGLCRRCSA GLGALAQRPG SVSKWVRLNV GGTYFLTTRQ 60
TLCRDPKSFL YRLCQADPDL DSDKDETGAY LIDRDPTYFG PVLNYLRHGK LVINKDLAEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCTGTGG CGGGGCTTGC TGGGATCATG GCGGAGAATC ACTGCGAGCT GCTGCCTCCG 60
GCCCCGGGCG GCCTCGGGGC GGGGCTGGGG GGCGGCCTGT GCCGGCGCTG CAGCGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR003131--T1-type_BTB

Pfam

PF02214--BTB_2

SMART

SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0097602--F:cullin family protein binding
GO:0032403--F:protein complex binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

KEGG

bta:100125308

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005071	Anolis carolinensis	96.34	3.00e-108	384.00
IUUC-Ame-011953	Astyanax mexicanus	65.53	7.00e-85	306.00
IUUC-Cfa-020368	Canis familiaris	97.86	8.00e-125	439.00
IUUC-Cpo-022539	Cavia porcellus	95.73	3.00e-122	430.00
IUUC-Cho-024408	Choloepus hoffmanni	75.00	4.00e-62	229.00
IUUC-Cin-025338	Ciona intestinalis	48.08	1.00e-19	90.50
IUUC-Csv-026375	Ciona savignyi	72.40	5.00e-83	300.00
IUUC-Dre-027599	Danio rerio	88.15	1.00e-98	352.00
IUUC-Dno-029324	Dasypus novemcinctus	94.02	2.00e-112	397.00
IUUC-Dor-030398	Dipodomys ordii	82.48	1.00e-101	362.00
IUUC-Dme-031661	Drosophila melanogaster	63.87	3.00e-65	240.00
IUUC-Eca-033240	Equus caballus	85.90	1.00e-111	395.00
IUUC-Eeu-034712	Erinaceus europaeus	45.90	9.00e-24	103.00
IUUC-Fal-037455	Ficedula albicollis	88.78	8.00e-105	372.00
IUUC-Gmo-039650	Gadus morhua	84.50	1.00e-98	351.00
IUUC-Gga-040799	Gallus gallus	73.25	2.00e-90	325.00
IUUC-Gac-042357	Gasterosteus aculeatus	79.91	4.00e-105	373.00
IUUC-Ggo-044563	Gorilla gorilla	96.58	1.00e-117	415.00
IUUC-Hsa-045899	Homo sapiens	96.58	1.00e-117	415.00
IUUC-Laf-053631	Loxodonta africana	95.71	3.00e-118	417.00
IUUC-Mcc-055489	Macaca mulatta	97.27	3.00e-109	387.00
IUUC-Mor-056957	Magnaporthe oryzae	36.49	1.00e-04	40.00
IUUC-Mga-059269	Meleagris gallopavo	89.38	6.00e-81	292.00
IUUC-Mmr-061170	Microcebus murinus	96.90	5.00e-113	400.00
IUUC-Mdo-063068	Monodelphis domestica	85.59	9.00e-110	389.00
IUUC-Mmu-064160	Mus musculus	95.30	5.00e-117	413.00
IUUC-Mpu-066707	Mustela putorius furo	95.30	3.00e-123	433.00
IUUC-Mlu-067096	Myotis lucifugus	97.01	5.00e-118	416.00
IUUC-Ont-072315	Oreochromis niloticus	87.56	4.00e-107	380.00
IUUC-Oan-072751	Ornithorhynchus anatinus	93.38	9.00e-83	298.00
IUUC-Ocu-074090	Oryctolagus cuniculus	96.58	2.00e-115	408.00
IUUC-Ola-087038	Oryzias latipes	85.92	1.00e-103	368.00
IUUC-Oga-088148	Otolemur garnettii	97.01	2.00e-117	414.00
IUUC-Oar-089499	Ovis aries	98.44	1.00e-93	335.00
IUUC-Pan-092829	Papio anubis	97.44	8.00e-118	416.00
IUUC-Pma-094233	Petromyzon marinus	39.68	4.00e-24	104.00
IUUC-Ppa-095886	Physcomitrella patens	34.82	2.00e-11	62.00
IUUC-Pfo-097467	Poecilia formosa	69.44	4.00e-93	333.00
IUUC-Pab-098083	Pongo abelii	81.62	6.00e-89	319.00
IUUC-Rno-104834	Rattus norvegicus	94.87	1.00e-116	411.00
IUUC-Smo-109623	Selaginella moellendorffii	37.40	5.00e-14	72.00
IUUC-Sar-113407	Sorex araneus	46.61	1.00e-23	103.00
IUUC-Tgu-116616	Taeniopygia guttata	93.55	2.00e-102	364.00
IUUC-Tru-118495	Takifugu rubripes	88.52	3.00e-108	384.00
IUUC-Tni-120558	Tetraodon nigroviridis	87.56	9.00e-108	382.00
IUUC-Ttr-129255	Tursiops truncatus	97.01	9.00e-125	439.00
IUUC-Xtr-132856	Xenopus tropicalis	89.22	4.00e-105	373.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence