iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020419

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03003542

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000023029.2	ENSCAFT00000023996.3	ENSCAFP00000022277.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.05	0.00e+00	1079.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MHKTTSQRLV PGSYQRIKRT MEDSTILRNQ TIGNKQKIKY DFSCELYRMS TYSTFPAGVP 60
VSERSLARAG FYYTGVNDKV KCFCCGLMLD NWKPGDNPVE KHKQLYPSCS FIHSLVSLTS 120

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Nucleotide Sequence
(Fasta)

ATGCACAAAA CTACTTCCCA AAGACTTGTC CCAGGTTCAT ATCAGAGGAT TAAGAGGACA 60
ATGGAGGATA GCACCATCTT ACGAAACCAG ACAATTGGCA ACAAACAAAA AATAAAATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0043027--F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:1990001--P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070266--P:necroptotic process
GO:0060546--P:negative regulation of necroptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	93.72	0.00e+00	1148.00
IUUC-Apl-003549	Anas platyrhynchos	72.20	0.00e+00	845.00
IUUC-Aca-004515	Anolis carolinensis	66.83	0.00e+00	781.00
IUUC-Aly-006460	Arabidopsis lyrata	41.67	2.00e-09	55.80
IUUC-Ame-011877	Astyanax mexicanus	55.14	0.00e+00	642.00
IUUC-Bta-012450	Bos taurus	87.70	0.00e+00	969.00
IUUC-Cja-018895	Callithrix jacchus	86.94	0.00e+00	1050.00
IUUC-Cpo-022048	Cavia porcellus	85.30	0.00e+00	1039.00
IUUC-Csa-024159	Chlorocebus sabaeus	81.53	0.00e+00	942.00
IUUC-Cho-024277	Choloepus hoffmanni	82.71	0.00e+00	989.00
IUUC-Cin-025521	Ciona intestinalis	31.07	2.00e-76	280.00
IUUC-Csv-026182	Ciona savignyi	30.11	9.00e-65	241.00
IUUC-Dre-028647	Danio rerio	54.85	0.00e+00	632.00
IUUC-Dno-029509	Dasypus novemcinctus	79.17	0.00e+00	941.00
IUUC-Dor-030796	Dipodomys ordii	72.03	4.00e-96	345.00
IUUC-Ete-032768	Echinops telfairi	65.75	0.00e+00	731.00
IUUC-Eca-033393	Equus caballus	90.48	0.00e+00	1075.00
IUUC-Eeu-035114	Erinaceus europaeus	83.01	0.00e+00	989.00
IUUC-Fca-036034	Felis catus	91.11	0.00e+00	1086.00
IUUC-Fal-037656	Ficedula albicollis	69.98	0.00e+00	847.00
IUUC-Gmo-038477	Gadus morhua	54.67	3.00e-177	615.00
IUUC-Gga-040601	Gallus gallus	70.49	0.00e+00	850.00
IUUC-Gac-041467	Gasterosteus aculeatus	56.59	1.00e-180	625.00
IUUC-Ggo-044857	Gorilla gorilla	87.40	0.00e+00	1061.00
IUUC-Hsa-045769	Homo sapiens	87.56	0.00e+00	1064.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	86.82	0.00e+00	1039.00
IUUC-Lch-050259	Latimeria chalumnae	61.83	0.00e+00	708.00
IUUC-Loc-052169	Lepisosteus oculatus	53.97	9.00e-168	583.00
IUUC-Laf-053449	Loxodonta africana	85.11	0.00e+00	1020.00
IUUC-Mcc-055282	Macaca mulatta	80.56	0.00e+00	944.00
IUUC-Meu-056241	Macropus eugenii	66.25	0.00e+00	702.00
IUUC-Mor-057252	Magnaporthe oryzae	33.33	2.00e-16	81.30
IUUC-Mga-059947	Meleagris gallopavo	70.29	0.00e+00	854.00
IUUC-Mvi-060388	Microbotryum violaceum	25.25	3.00e-07	50.40
IUUC-Mdo-062352	Monodelphis domestica	76.33	0.00e+00	923.00
IUUC-Mmu-064340	Mus musculus	82.42	0.00e+00	986.00
IUUC-Mpu-065890	Mustela putorius furo	92.46	0.00e+00	1026.00
IUUC-Mlu-068077	Myotis lucifugus	88.03	0.00e+00	1071.00
IUUC-Nle-070081	Nomascus leucogenys	86.43	0.00e+00	1063.00
IUUC-Opr-070561	Ochotona princeps	80.23	0.00e+00	970.00
IUUC-Ont-071776	Oreochromis niloticus	52.17	0.00e+00	631.00
IUUC-Oan-073604	Ornithorhynchus anatinus	75.78	0.00e+00	880.00
IUUC-Ocu-073963	Oryctolagus cuniculus	87.46	0.00e+00	1016.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	5.00e-07	48.90
IUUC-Oni-082044	Oryza nivara	41.82	3.00e-09	56.60
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Ola-086446	Oryzias latipes	52.33	2.00e-171	595.00
IUUC-Oga-087976	Otolemur garnettii	88.53	0.00e+00	1065.00
IUUC-Oar-090097	Ovis aries	88.30	0.00e+00	1088.00
IUUC-Ptr-091137	Pan troglodytes	87.72	0.00e+00	1065.00
IUUC-Pan-092673	Papio anubis	88.85	0.00e+00	1079.00
IUUC-Psi-092992	Pelodiscus sinensis	70.86	0.00e+00	842.00
IUUC-Ppa-095167	Physcomitrella patens	42.86	2.00e-11	63.20
IUUC-Pfo-096790	Poecilia formosa	53.86	7.00e-174	603.00
IUUC-Pab-098734	Pongo abelii	88.46	0.00e+00	1041.00
IUUC-Pop-098944	Populus trichocarpa	42.59	6.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	74.60	2.00e-175	608.00
IUUC-Pva-102788	Pteropus vampyrus	89.18	0.00e+00	1087.00
IUUC-Rno-105026	Rattus norvegicus	79.73	0.00e+00	943.00
IUUC-Sha-107229	Sarcophilus harrisii	70.32	0.00e+00	848.00
IUUC-Ssc-115804	Sus scrofa	85.83	0.00e+00	1043.00
IUUC-Tgu-116931	Taeniopygia guttata	71.19	0.00e+00	865.00
IUUC-Tru-117620	Takifugu rubripes	52.88	3.00e-177	615.00
IUUC-Tsy-118958	Tarsius syrichta	68.99	1.00e-150	526.00
IUUC-Tni-119683	Tetraodon nigroviridis	53.15	3.00e-176	612.00
IUUC-Tbe-127523	Tupaia belangeri	88.21	0.00e+00	1073.00
IUUC-Ttr-128954	Tursiops truncatus	85.81	0.00e+00	1041.00
IUUC-Vpa-130441	Vicugna pacos	86.73	0.00e+00	1062.00
IUUC-Xtr-132031	Xenopus tropicalis	56.83	0.00e+00	639.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence